Get the Daily Brief
Latest Biotech News
FDA Clears Pembrolizumab for Resectable Head and Neck Cancer
The FDA approved pembrolizumab for patients with resectable locally advanced head and neck squamous cell carcinoma expressing PD-L1, marking the first checkpoint inhibitor approval in this...
Wojcicki’s Nonprofit Tops Regeneron in 23andMe Bid
Anne Wojcicki’s nonprofit TTAM Research Institute secured 23andMe’s assets in a $305 million deal, outbidding Regeneron and committing to stringent privacy protections and continued data use for...
ADC Therapeutics Shuts UK Site, Cuts Workforce by 30%
After discontinuing its only clinical-stage candidate, ADC Therapeutics announced the closure of its UK R&D site and a 30% workforce reduction. The restructuring focuses resources on approved...
FDA Approvals and Regulatory Updates: Head and Neck Cancer, Bladder Cancer, RSV
The FDA has approved pembrolizumab for resectable locally advanced head and neck squamous cell carcinoma patients with PD-L1 expression, based on the KEYNOTE-689 Phase 3 trial demonstrating...
23andMe Asset Acquisition: Anne Wojcicki’s Nonprofit Bid Wins
A bidding war for 23andMe culminated with former CEO Anne Wojcicki’s nonprofit, TTAM Research Institute, winning the auction with a $305 million offer that surpasses Regeneron’s $256 million bid....
Parkinson’s Disease: Multi-Omics Treatment, Subtype Correlates, and Brain Impairments
New Parkinson’s disease research highlights drug repurposing opportunities through integrative multi-omics analysis revealing memory-enhancing effects of meclofenoxate hydrochloride. Studies...
Cancer Therapy Advances: Novel Combinations and CAR-T Improvements
A recent early-phase trial combining revumenib, a menin inhibitor, with established AML treatments showed promising remission rates in genetically defined acute myeloid leukemia patients, leading...
Quantum and Optical Technology: Optical Clocks and Brain Imaging Breakthroughs
An international collaboration achieved the most extensive simultaneous comparison of optical atomic clocks across six countries, paving the way to redefine the second and enabling new...
AI Applications: Biologically Inspired Neural Network Training
Researchers at the Technical University of Munich demonstrated that artificial neural networks pretrained using biological data from early visual system development in mice outperform models...
Environmental and Energy Innovations: Cooling Tech and Lithium Supply Challenges
Engineers at UC San Diego unveiled an evaporative cooling technology utilizing porous fiber membranes that passively dissipate heat, aiming to drastically improve data center energy efficiency and...
Biotechnology Legislation and Industry Impact: Reconciliation Bill and ORPHAN Cures Act
Pending U.S. legislative proposals include important biotechnology provisions such as the ORPHAN Cures Act, which addresses rare disease drug pricing and aims to restore incentives for developing...
Microbiome and Cancer: Fusobacterium nucleatum in Colorectal Cancer
Recent comprehensive reviews outline the pathogenic role of Fusobacterium nucleatum in colorectal cancer, including its influence on tumor initiation, progression, metastasis and resistance to...
Vascular Organoids: Rapid Generation via Transcription Factor Activation
A novel method developed by Boston Children's Hospital and Harvard Medical School allows the rapid creation of functional vascular organoids from human stem cells by co-activating endothelial and...
Pharma Budget Bill Drivers: Orphan Drug Wins, Pricing Reforms
Key provisions in the US budget bill under Senate consideration aim to reshape biopharma innovation and pricing. The package proposes reforms to the Inflation Reduction Act's orphan drug...
Anne Wojcicki Secures 23andMe in Nonprofit Takeover Bid
Anne Wojcicki, co-founder and former CEO of 23andMe, won a competitive bidding process to purchase the company for $305 million through her nonprofit, the TTAM Research Institute. The deal...
ADC Therapeutics Restructures: UK Site Closure, Job Cuts
ADC Therapeutics announced the shutdown of its UK research and development site along with a 30% workforce reduction, in a strategic move to concentrate resources on its approved monoclonal...
AI-Generated Science Podcasts Stir Debate Over Traditional Media Future
A recent study in the European Journal of Cardiovascular Nursing explored artificial intelligence's capability to generate scientific podcasts using tools like Google NotebookLM. The AI-produced...
US Biopharma Industry Faces Regulatory and Financial Shifts
The ongoing budget bill debates in Congress include significant impacts on biopharma, featuring reforms to the Inflation Reduction Act that affect orphan drugs and price negotiation exemptions....
23andMe Sold to Nonprofit Led by Co-Founder in Competitive Bid
Anne Wojcicki, co-founder and former CEO of 23andMe, outbid Regeneron by securing the company's assets in a $305 million purchase through her nonprofit TTAM Research Institute. The deal ensures...
FDA Approves Checkpoint Inhibitor Pembrolizumab for Head and Neck Cancer
The FDA granted approval to pembrolizumab for patients with resectable locally advanced head and neck squamous cell carcinoma expressing PD-L1, following the KEYNOTE-689 phase 3 trial. The...