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Federal Circuit remands Guardant patent case to appeals board
The U.S. Court of Appeals for the Federal Circuit remanded a patent infringement dispute involving Guardant Health, TwinStrand Biosciences, and the University of Washington back to the Patent...
Protein‑sequencing start‑up Encodia shutters — assets headed to auction
Encodia, a San Diego protein‑sequencing company that developed a DNA‑tagging peptide readout called ProteoCode, ceased operations and initiated an assignment for the benefit of creditors. The...
Venter‑backed Diploid Genomics launches with seed funding
A new spinout, Diploid Genomics, cofounded by J. Craig Venter, launched with undisclosed seed funding from Healthier Capital. The company plans an AI‑driven genomics analytics platform that...
EU rolls out FAST‑EU pilot: 70‑day target to start multinational trials
The European Union launched FAST‑EU, a voluntary one‑year pilot designed to accelerate multinational clinical trial start‑up timelines. The program sets a maximum 70‑day (10‑week) timeline from...
FDA drafts guidance for cuffless blood‑pressure monitors — oversight tightens
The FDA’s Center for Devices and Radiological Health released a draft guidance proposing regulatory expectations for cuffless blood‑pressure monitoring devices. The agency aims to clarify...
F2G plans olorofim FDA resubmission after collecting Phase 3 data
F2G’s chief executive said the antifungal developer plans to resubmit olorofim to the FDA after completing Phase 3 data collection expected this June. Olorofim, an oral antifungal targeting...
Erasca raises $258.8m in upsized offering
Erasca closed an upsized public offering that generated roughly $258.8 million in gross proceeds, the company said in a Globe Newswire filing. The financing sold 25.875 million shares at $10.00...
Protein sequencing startup Encodia folds... auctions lab equipment
Encodia, a San Diego protein‑sequencing company that developed a DNA‑tagging approach called ProteoCode, ceased operations late last year and is liquidating lab assets, GenomeWeb reported. The...
Appeals court remands Guardant patent case to PTAB – damages in flux
A U.S. appeals court remanded Guardant Health’s patent lawsuit with TwinStrand Biosciences to the Patent Trial and Appeal Board for additional validity review, potentially altering earlier jury...
Novo’s Wegovy pill surges: prescriptions jump 500% in week two
Novo Nordisk’s oral Wegovy (semaglutide) pill saw a rapid uptake in the U.S., with prescriptions reported to have increased roughly 500% in its second week on the market, analysts noted. The early...
Corxel banks $287m to advance oral GLP‑1 CX‑11
Corxel Pharmaceuticals closed a $287 million Series D to push its oral small‑molecule GLP‑1 agonist CX‑11 through U.S. and planned global Phase II trials and begin Phase III preparations. The...
Sanofi to file for amlitelimab despite mixed Phase 3 reads
Sanofi said it will pursue global regulatory submissions for amlitelimab, an OX40‑ligand (OX40L) inhibitor for atopic dermatitis, despite mixed late‑stage results across trials. Company statements...
Venter cofounds Diploid Genomics: AI‑driven genomics analytics spinout
A new JCVI spinout, Diploid Genomics, launched with seed backing from Healthier Capital and plans to combine long‑read sequencing, imaging and AI models for discovery and diagnostics. Cofounders...
Macrophage‑targeting CAR T reshapes tumors: preclinical survival gains
Researchers at the Icahn School of Medicine at Mount Sinai reported that IL‑12–producing CAR T cells engineered to target tumor‑associated macrophages (TAMs) improved survival and controlled...
Mendra nets $82m to build rare‑disease portfolio using AI
Mendra closed an $82 million Series A to acquire, develop and commercialize treatments for rare diseases, the company said. The financing was co‑led by OrbiMed, 8VC and 5AM Ventures, with...
Diagnostics and pathology tools roll out: Tempus Predict, Navinci, Zepto; FDA clears 4‑in‑1 home test
Several diagnostic and pathology vendors unveiled new products and services this week. Tempus launched Paige Predict, an AI pathology suite that estimates biomarker presence across cancer types;...
Erasca upsizes offering: $258.8M raised to fund RAS/MAPK programs
Erasca closed an upsized public offering, selling 25.875 million shares at $10 each to raise roughly $258.8 million before fees. The San Diego-based precision oncology company said proceeds will...
Corxel lands $287M series D to push oral GLP‑1 CX‑11 into phase III preparation
Corxel Pharmaceuticals raised $287 million in a Series D round to advance CX‑11, an oral small‑molecule GLP‑1 receptor agonist for obesity and overweight patients. The company said funds will...
Wegovy pill demand surges: prescriptions spike and market reaction follows
Novo Nordisk’s oral formulation of semaglutide—marketed as an oral Wegovy pill—saw prescription volumes ramp sharply in its early weeks on the market, with analysts reporting roughly a 500%...
Encodia collapse: protein‑sequencing startup shutters, assets up for auction
Encodia, the San Diego protein sequencing company that developed ProteoCode (DNA‑tagged peptide readout), ceased operations late last year and is conducting an assignment for the benefit of...