Get the Daily Brief
Latest Biotech News
Scholar Rock’s Myostatin Blocker Preserves Lean Mass with Obesity Treatment
In a Phase 2 study, Scholar Rock’s apitegromab, an anti-myostatin antibody, was shown to preserve lean muscle mass in patients undergoing weight loss therapy with Eli Lilly’s Zepbound...
FDA Overhauls Drug Review Process Amid Leadership Changes
The U.S. Food and Drug Administration (FDA) is undergoing significant shifts in leadership and procedural reforms aimed at accelerating drug approval timelines. Key cell and gene therapy leaders...
Gilead’s Twice-Yearly HIV Prevention Shot Gains FDA Approval
The FDA approved Gilead Sciences’ lenacapavir (commercially Yeztugo), a long-acting injectable pre-exposure prophylaxis (PrEP) treatment against HIV that requires just two injections annually....
Lilly’s $1.3B Bet on Gene Therapies for Cardiovascular Disease
Eli Lilly advanced its gene therapy pipeline with a $1.3 billion acquisition of CRISPR startup Verve Therapeutics, adding VERVE-102, an in vivo CRISPR base editor targeting PCSK9 for...
Financial Strain Widens Among Biotech Firms: EY Reports
The latest EY Biotech Beyond Borders report reveals that nearly 40% of biotech companies face cash runways shorter than 12 months — the highest level in over six years. This alarming trend...
Artificial Cells Production Breakthrough Using Microfluidics
Researchers led by Professor Hiroaki Suzuki at Chuo University have pioneered a microfluidic-based technology for mass-producing uniform artificial cells containing DNA condensates simulating...
Zealand Pharma’s GLP-1/GLP-2 Dual Agonist Shows Promising Weight Loss Results
Zealand Pharma reported updated phase 1b trial data for its dual GLP-1/GLP-2 receptor agonist dapiglutide, with patients on higher dosing regimens experiencing mean body weight reductions of 11.6%...
Qiagen Launches Digital PCR Partnering Program for Oncology Assays
Qiagen has initiated a third-party partnering program to expand its clinical digital PCR platform's test menu, signing South Korea-based Gencurix Oncology as the inaugural partner. The...
Advances in Single-Cell and Spatial Omics Illuminate PTSD Mechanisms
Cutting-edge single-cell transcriptomic and epigenomic analyses have elucidated molecular and cellular alterations underpinning post-traumatic stress disorder (PTSD). Studies have identified...
Biofilm-Resistant Surface Patterns Combat Medical Device Infections
Researchers at the University of Nottingham have developed innovative microtopographical patterns on plastic surfaces that drastically inhibit bacterial adhesion and biofilm formation, a leading...
AI Integration Enhances Genomic Variant Interpretation in Cancer Diagnostics
A strategic partnership between Intelliseq and Genomenon integrates the Cancer Knowledgebase (CKB) somatic variant data into Intelliseq’s iFlow platform, improving clinical interpretation of tumor...
FDA launches pilot program to accelerate drug reviews for national priorities
FDA Commissioner Martin Makary introduced a pilot Commissioner’s National Priority Voucher program aimed at drastically reducing drug review times for products meeting defined U.S. national...
Gilead secures FDA approval for twice-yearly HIV prevention shot
The FDA approved Gilead Sciences’ lenacapavir (Yeztugo) as a revolutionary pre-exposure prophylaxis (PrEP) option for HIV prevention, requiring only two injections annually. The approval follows...
Emerging antibody therapies advance in oncology and autoimmune diseases
Recent clinical developments highlight novel antibody-based therapeutics showing promise across cancer and autoimmune disorders. Aptevo Therapeutics’ mipletamig updated data reveal an 85%...
Breakthroughs in cancer genomics and precision diagnostics
Several institutions report advances in cancer genomic profiling and diagnostics. Caris Life Sciences completed a $494 million IPO highlighting their AI-driven multimodal clinico-genomic platform...
Innovations in AI and machine learning for drug discovery and healthcare
Artificial intelligence applications continue to transform biotech and healthcare sectors. Nutcracker Therapeutics develops open-source RNA manufacturing platforms optimized for personalized mRNA...
Microfluidic technology enables mass production of artificial cells with model nuclei
Researchers at Chuo University have pioneered a microfluidics-based methodology for the high-throughput fabrication of artificial cells containing model DNA condensates mimicking eukaryotic...
Advances in neuroscience reveal mechanisms underpinning brain health and disorders
Cutting-edge studies illuminate molecular and cellular mechanisms relevant to brain aging, PTSD, and Parkinson’s disease. Research at Salk Institute highlights neuron-to-glia communication...
Novel approaches to cancer treatment and tumor microenvironment targeting
Research and development progress in cancer therapeutics is marked by innovative strategies targeting tumor biology and microenvironments. Genentech describes inhibitors targeting KRAS G12D...
Expanding precision medicine with epigenetics and genomic editing breakthroughs
Groundbreaking genetic and epigenetic advances offer new therapeutic avenues and insights into disease mechanisms. Hubrecht Institute researchers report a method to reactivate silenced genes by...