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Gene Regulation and Evolutionary Biology Insights
Researchers reveal new insights into gene regulation and evolutionary mechanisms with broad implications. Studies of de novo genes in Drosophila identify key transcription factors accounting for...
Innovations in Battery and Energy Storage Technologies
Recent breakthroughs in battery science promise safer, more efficient energy storage solutions. Novel quasi-solid electrolytes for lithium-ion and magnesium batteries enhance stability and...
Artificial Intelligence Applications in Biotech and Healthcare
Artificial intelligence continues to revolutionize diverse aspects of biotechnology and medicine. Novel AI platforms accelerate drug discovery, enabling large-scale data generation and molecular...
Agricultural and Environmental Biotechnology Innovations
Innovative research tackles critical challenges in agriculture and environmental sustainability. Advances in breeding climate-resilient crops and digital twin frameworks enhance modular building...
AI Accelerates Antibiotic Development Against Drug-Resistant Bacteria
Researchers at MIT and collaborators have harnessed generative AI to design novel antibiotics targeting drug-resistant pathogens like Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus...
Novel CD40 Agonist Shows Systemic Efficacy in Metastatic Cancer Trial
A Phase I clinical trial evaluated the Fc-optimized CD40 agonistic antibody 2141.V11 administered intratumorally in metastatic cancer patients. The study reported tumor shrinkage in half of the 12...
Schrödinger Discontinues CDC7 Inhibitor After Treatment-Related Deaths
Schrödinger halted development of SGR-2921, a cell division cycle 7 (CDC7) inhibitor for acute myeloid leukemia and high-risk myelodysplastic syndromes, following two patient deaths linked to the...
Superluminal and Lilly Ink $1.3 Billion Pact on GPCR Cardiometabolic Drugs
Superluminal Medicines secured up to $1.3 billion in a collaboration deal with Eli Lilly to develop small-molecule therapies targeting undisclosed G protein-coupled receptors (GPCRs) implicated in...
Bayer and Kumquat Partner on $1.3 Billion KRAS G12D Inhibitor Development
Bayer AG entered an exclusive global collaboration with San Diego-based Kumquat Biosciences to develop and commercialize Kumquat’s KRAS G12D inhibitor, a first-in-class agent targeting a key...
Breakthrough Brain-Computer Interface Enables Communication via Inner Speech
Neuroscientists developed a brain-machine interface capable of decoding inner speech by interpreting neural signals from the motor cortex involved in imagined speech. Tested in patients with...
AI Models Design Peptides to Target ‘Undruggable’ Disease Proteins
Researchers at the University of Pennsylvania introduced PepMLM, an AI-driven protein language model designed to develop peptide binders for challenging therapeutic targets lacking resolved...
Spatial Proteomics Firm Syncell Expands with Thermo Fisher Partnership
Taiwanese spatial proteomics company Syncell inked a comarketing agreement with Thermo Fisher Scientific to integrate Syncell’s Microscoop platform for spatial protein purification with Thermo...
New AI-Powered Radiomics Model Predicts Breast Cancer Metastasis
A multicenter study developed a radiomics model based on contrast-enhanced ultrasound imaging that accurately predicts axillary lymph node metastasis and prognosis in breast cancer patients. This...
Intensive AI and Genomics Integration Elevates Cancer Risk Stratification
A novel histology-based risk prediction tool, HIBRID, combines machine learning and circulating tumor DNA analysis to transform colorectal cancer management. Published in Nature Communications,...
Cancer Antibody Trial Shows Complete Responses in Metastatic Patients
A Phase I clinical trial evaluating an engineered CD40 agonistic antibody (2141.V11) demonstrated promising anti-tumor activity in 12 metastatic cancer patients, including melanoma and breast...
Drug Pricing Strategies Shift Amid U.S. Policy Pressure
Eli Lilly announced plans to increase drug prices in Europe and other developed markets in response to the U.S. government's “most-favored-nation” policy under the Trump administration, aiming to...
Breakthrough in Protein Evolution Speeds Therapeutic Development
Researchers at Scripps Research led by Peter Schultz developed T7-ORACLE, a synthetic biology system that accelerates directed evolution of proteins within living cells by harnessing an...
Major Biotech Funding and Strategic Collaborations Spark Innovation
Several biopharmaceutical companies secured substantial funding rounds and forged key partnerships to enhance development pipelines and manufacturing capabilities. Superluminal Medicines entered a...
AI and Computational Advances Transform Drug Discovery and Diagnostics
Artificial intelligence is increasingly integrated into biotechnology, boosting drug design and biomedical research. Researchers at the University of Pennsylvania developed PepMLM, a protein...
New Insights into Obesity Genetics and Predictive Risk Models
A large international consortium enhanced polygenic risk scores (PRS) for obesity by integrating extensive genomic data from over five million participants across diverse ancestries. The improved...