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Revolution in Brain-Computer Interfaces Enables Communication via Inner Speech
Researchers have engineered a brain-computer interface (BCI) system that allows users to communicate by decoding neural signals associated with inner speech, rather than attempted speech....
MIT Harnesses AI to Design Antibiotics Against Drug-Resistant Bacteria
Researchers at the Massachusetts Institute of Technology (MIT) have utilized generative artificial intelligence (AI) to design novel antibiotic compounds targeting highly resistant bacteria such...
Schrödinger Halts CDC7 Inhibitor Development After Patient Deaths
Schrödinger has discontinued development of its CDC7 inhibitor drug candidate, SGR-2921, following the deaths of two patients with acute myeloid leukemia (AML) during a phase I dose-escalation...
Eli Lilly Raises Drug Prices in Europe to Lower U.S. Costs
Eli Lilly announced plans to significantly increase the list prices of its drugs, including the weight-loss medication Mounjaro, across European markets such as the United Kingdom. This strategic...
Congress Reinstates Vaccine Safety Task Force Amid Controversy
The U.S. Department of Health and Human Services (HHS) has announced the reinstatement of the long-defunct Task Force on Safer Childhood Vaccines, originally disbanded in 1998. This move follows a...
Cutting-Edge CUT&Tag Modification Enables Transcription Factor Binding Analysis
Scientists at the University of Cologne have innovated on the CUT&Tag chromatin accessibility assay by optimizing buffer salt concentrations, enabling the detection of transcription factor binding...
Breakthrough in Non-Invasive Real-Time Imaging of Human Embryo Implantation
Researchers at the Institute for Bioengineering of Catalonia, in collaboration with Dexeus University Hospital, have successfully recorded, for the first time, the three-dimensional real-time...
HHS Revives Vaccine Safety Panel Amid Controversy
The U.S. Department of Health and Human Services has reinstated the Task Force on Safer Childhood Vaccines, a panel originally disbanded in 1998, aiming to improve vaccine safety and oversight for...
Precigen's Gene Therapy Secures FDA Approval for Rare Lung Disease
Precigen Inc. received swift full FDA approval for Papzimeos (zopapogene imadenovec), a gene therapy treating recurrent respiratory papillomatosis (RRP), characterized by benign respiratory tract...
Eli Lilly’s Pricing Strategy Sparks Global Market Shuffle
Eli Lilly plans steep price increases for its weight-loss drug Mounjaro in the U.K., raising the highest dose price by 170%, aiming to lower U.S. prices amidst pressure from the Trump...
AI-Powered Antibiotic Discovery Targets Drug-Resistant Bacteria
Researchers at MIT employed generative artificial intelligence to design novel antibiotic compounds effective against multidrug-resistant Neisseria gonorrhoeae and MRSA. Screening millions of...
Schrödinger Halts Blood Cancer Drug Trials After Fatalities
Schrödinger discontinued its CDC7 inhibitor SGR-2921 development following the deaths of two AML patients in a Phase I trial. Despite promising preclinical and early monotherapy activity, safety...
Breakthrough in Brain-Computer Interfaces Enables Inner Speech Communication
Researchers have developed a novel brain-computer interface that decodes imagined speech from motor cortex activity, enabling paralyzed patients to communicate by thinking words rather than...
Cancer Immunotherapy Shows Promise with Systemic Effects from Local Delivery
A Phase I clinical trial demonstrated remarkable tumor regression in metastatic cancer patients using an Fc-optimized CD40 agonist antibody injected directly into tumors. Six out of twelve...
Genetic Insights into Human-Specific Brain Development via HAR123 Enhancer
Scientists at UC San Diego identified a rapidly evolving human-accelerated region (HAR123) that functions as a transcriptional enhancer affecting genes involved in neural development and cognitive...
Spatial Proteomics Expands with New Integrations and Market Growth
Syncell, a Taiwanese spatial proteomics company, has entered a co-marketing agreement with Thermo Fisher Scientific to integrate MicroScoop protein purification technology with Thermo Fisher’s...
AI Powers Antibiotic Design for Resistant Infections
Researchers at MIT have harnessed artificial intelligence to design novel antibiotics targeting drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA). By...
FDA Review Turmoil and Sarepta Safety Data in Rare Disease Drugs
The FDA faces scrutiny amid complex regulatory challenges highlighted by Sarepta Therapeutics’ Duchenne muscular dystrophy gene therapy safety concerns, including cases of acute liver failure...
Eli Lilly Raises Drug Prices Abroad Amid US Pricing Pressure
Eli Lilly announced plans to increase drug list prices in Europe, including a triple price hike for its obesity drug Mounjaro in the UK, aiming to offset US pricing pressures linked to the Trump...
Breakthrough Cancer Immunotherapy Shows Systemic Responses
A first-in-human trial of an Fc-optimized CD40 agonistic antibody, 2141.V11, demonstrated promising systemic tumor regression in metastatic cancer patients. Delivered via intratumoral injection,...