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BioElectronics-Assisted Implant Enables Oxygenated Insulin Cell Delivery
Cornell University researchers engineered the BEAM system, a continuously oxygenated macroencapsulation device that supports high-density packing and delivery of insulin-secreting cells without...
Clinical Advances Highlight Dual Therapy in Bladder Cancer Survival
Pfizer and Merck reported compelling survival benefits from combining Pfizer's antibody-drug conjugate Padcev with Merck’s Keytruda in patients with muscle-invasive bladder cancer deemed...
Molecular Evolution System Accelerates Protein Engineering
A team led by Scripps Research’s Peter Schultz developed T7-ORACLE, a synthetic biology platform leveraging an engineered T7 bacteriophage replisome to drive rapid, continuous, and precise protein...
Bayer and Kumquat Strike $1.3 Billion Deal on KRAS G12D Cancer Inhibitor
Bayer AG and Kumquat Biosciences have entered an exclusive global licensing and collaboration agreement to develop and commercialize Kumquat's KRAS G12D inhibitor, a first-in-class drug candidate...
FDA Approves Insmed’s Brensocatib as First Drug for Non-Cystic Fibrosis Bronchiectasis
The U.S. Food and Drug Administration (FDA) has approved Insmed's Brensocatib, branded as Brinsupri, for the treatment of non-cystic fibrosis bronchiectasis (NCFB) in adults and children 12 years...
AI-Driven Advances Transform Cancer Biomarker Discovery and Drug Design
Recent breakthroughs leverage artificial intelligence to accelerate and refine cancer research. Teams at the University of Zurich developed 'Pythia,' an AI tool that predicts DNA repair outcomes...
Novartis Secures Dual Phase III Wins with Anti-BAFF-R Antibody in Autoimmune Diseases
Novartis announced significant clinical successes for its monoclonal antibody ianalumab, which demonstrated efficacy in Phase III trials for Sjögren’s disease and primary immune thrombocytopenia...
mRNA Vaccine Research Faces Federal Funding Retrenchment Amid Public Trust Concerns
Following a recent directive by Health and Human Services (HHS) Secretary Robert F. Kennedy Jr., the Biomedical Advanced Research and Development Authority terminated multiple grants supporting...
Breakthroughs in Diabetes and Obesity Drug Development Highlight Industry Momentum
Lilly overtook Novo Nordisk in sales of GLP-1 receptor agonists across diabetes and obesity markets by Q2 2025, signaling intensified competition in this expanding therapeutic area. The company...
Innovative Technologies and Platforms Accelerate Biomanufacturing and Diagnostics
Researchers at North Carolina State University achieved dramatic pDNA yield enhancements by controlling E. coli evolution, a step that promises to lower gene therapy manufacturing costs....
Groundbreaking Neuroscience Insights from Organoids and Stem Cell Research
Neural organoids are revolutionizing neuroscience research by enabling complex studies of human brain development, disease modeling, and therapeutic discovery previously inaccessible through...
New Frontiers in Cancer Immunotherapy and Resistance Mechanisms
Recent studies reveal novel therapeutic targets and resistance pathways in cancer treatment. Research identified EPIC1 long noncoding RNA as a driver of immunotherapy resistance in triple-negative...
Bayer and Kumquat Strike $1.3 Billion KRAS G12D Cancer Deal
Bayer AG has entered a global exclusive license and collaboration with Kumquat Biosciences to develop and commercialize Kumquat's KRAS G12D inhibitor, targeting one of the most prevalent oncogenic...
Insmed’s Brinsupri Approved as First Drug for Non-CF Bronchiectasis
The FDA has approved Insmed’s Brinsupri (brensocatib), the first therapy specifically indicated for the treatment of non-cystic fibrosis bronchiectasis (NCFB), a chronic respiratory disease...
AI-Driven Advances Transform Gene Editing and Drug Design
Researchers have integrated artificial intelligence into genetic engineering to significantly enhance precision and efficiency. The University of Zurich team developed Pythia, an AI model...
Broad-Spectrum mRNA Antiviral Emerges from Rare Immune Disorder Study
Inspired by insights into ISG15 deficiency, researchers at Columbia University engineered an mRNA-based antiviral showing broad activity against diverse viruses including Zika, SARS-CoV-2, and...
Novel Lithium Battery and Energy Storage Technologies Advance
Recent studies have introduced innovative materials and methods enhancing lithium and zinc battery performance. Researchers from Helmholtz-Zentrum Berlin used neutron tomography to clarify...
Cancer Immunotherapy and Target Discovery Make New Headway
Multiple pioneering cancer research studies have unveiled promising therapeutic targets and treatment strategies. The University of Pittsburgh identified lncRNA EPIC1 as a driver of immune evasion...
mRNA Vaccine Funding Faces Federal Withdrawal Amid Trust Concerns
The Biomedical Advanced Research and Development Authority (BARDA) terminated 22 grants supporting mRNA vaccine development, resulting in withdrawal of nearly $500 million in federal funding. This...
Breakthroughs in Neuroscience with Human Brain Organoids
Neural organoids are advancing research in human brain development and disease modeling, providing unprecedented biological insight. Researchers at University of California San Diego and the...