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AI-Enabled Brain-Computer Interface Decodes Inner Speech
Neuroscientists developed a brain-computer interface (BCI) capable of translating neural signals from the motor cortex associated with inner speech into real-time text. Tested on patients with...
Spatial Proteomics Advances via Syncell-Thermo Fisher Partnership
Taiwanese spatial proteomics firm Syncell entered a co-marketing agreement with Thermo Fisher Scientific integrating Syncell’s Microscoop protein purification system with Thermo Fisher’s Orbitrap...
Advances in Targeted Cancer Therapies and Clinical Trials
Innovations are emerging in targeted therapies for solid tumors including trispecific T-cell engager EVOLVE-104 from Evolveimmune with FDA IND clearance, and new antibody-drug conjugates targeting...
Precision and AI in Cancer and Diagnostics
Machine learning and AI technologies are revolutionizing cancer diagnostics and drug discovery. Innovations include an AI-powered method for detecting ignition in inertial confinement fusion...
Cutting-Edge Developments in Energy Storage and Battery Technology
Researchers have achieved breakthroughs in battery materials and electrolytes, including the development of a quasi-solid 3D-SLISE electrolyte for lithium-ion batteries offering safety and...
AI Designs Novel Antibiotics Targeting Drug-Resistant Bacteria
Researchers at MIT have harnessed generative AI to design new antibiotic molecules effective against drug-resistant bacteria such as Neisseria gonorrhoeae and MRSA. The approach involved...
Immunotherapy Shows Promise in Advanced Skin Cancer Treatment
A clinical study from UCLA demonstrated that pembrolizumab, an immunotherapy targeting the PD-1 receptor, induced durable tumor regression in patients with unresectable desmoplastic melanoma, a...
Groundbreaking Inner Speech Brain-Computer Interface Enables Communication
Neuroscientists have unveiled a novel brain-computer interface allowing individuals with severe paralysis to communicate by decoding neural signals corresponding to inner speech. Unlike previous...
CD40 Agonist Antibody Yields Tumor Shrinkage in Metastatic Cancer Trial
A first-in-human Phase I trial of an Fc-optimized CD40 agonistic antibody, 2141.V11, delivered intratumorally, has demonstrated preliminary clinical efficacy in metastatic cancer patients. Among...
Major Biotech Deal Targets Undruggable KRAS G12D Mutation
Bayer and Kumquat Biosciences have entered an exclusive $1.3 billion collaboration to develop and commercialize inhibitors targeting the KRAS G12D mutation, a driver in multiple hard-to-treat...
NIH and US Agencies Scale Back mRNA Vaccine Funding Amid Public Trust Concerns
The US government is withdrawing funding and partnerships supporting mRNA vaccine research for respiratory diseases, citing public trust issues. Despite mRNA vaccine technology’s success in...
Artificial Intelligence Accelerates RNA Therapeutics via Lipid Nanoparticle Design
Researchers at MIT have applied artificial intelligence to streamline the design of lipid nanoparticle (LNP) carriers for RNA vaccines and therapeutics. This work aims to overcome challenges in...
Schrödinger Halts AML Drug Development After Patient Deaths in Trial
Schrödinger has discontinued development of SGR-2921, a CDC7 inhibitor for acute myeloid leukemia (AML), after two patients died in a Phase I dose-escalation study, with the drug considered a...
Syncell and Thermo Fisher Partner to Expand Spatial Proteomics Access
Taiwanese spatial proteomics company Syncell has entered a co-marketing agreement with Thermo Fisher Scientific to integrate Syncell's Microscoop spatial protein purification system with Thermo...
Natural Killer Cell Function Modulated by Serine Metabolism
Recent findings illuminate how serine metabolism intricately regulates natural killer (NK) immune cell functions. Rapid metabolic reprogramming enables NK cells to meet their energy and...
AI-Driven Antibiotics Target Drug-Resistant Bacteria
Researchers at MIT have harnessed generative artificial intelligence to design novel antibiotic molecules effective against drug-resistant Neisseria gonorrhoeae and multi-drug-resistant...
FDA and Biotech Industry Regulatory Developments
The US FDA is undergoing significant transformations amid increasing political and operational pressures. Recent efforts include the launch of the FDA PreCheck program to expedite domestic...
Advancements in Immunotherapies for Cancer
Significant clinical and preclinical advances in cancer immunotherapy have emerged. UCLA-led studies demonstrate pembrolizumab's ability to induce sustained regressions in advanced desmoplastic...
Sustainable Agriculture and Crop Yield Innovations in China
Multiple studies highlight China's advances in sustainable crop production. Researchers elucidate strategies to boost corn and rice yields while improving resource efficiency and mitigating...
Breakthroughs in Neurodegenerative and Psychiatric Disorders Research
Pivotal studies elucidate mechanisms and therapeutic avenues in neurodegeneration and psychiatry. Mount Sinai researchers link prenatal acetaminophen exposure to heightened autism and ADHD risks....