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Pliant Therapeutics Halts IPF Program Citing Safety Concerns
Pliant Therapeutics has discontinued its idiopathic pulmonary fibrosis (IPF) development program after a detailed assessment revealed an increase in adverse events in a Phase 2b/3 clinical trial...
Thermo Fisher-Tufts Study Finds Integrated CRO-CDMO Model Cuts Cancer Drug Development Nearly Three Years
A white paper by the Tufts Center for the Study of Drug Development, commissioned by Thermo Fisher Scientific, shows that their integrated Accelerator platform combining contract development and...
Genetically Modified E. coli Converts Plastic Waste Into Paracetamol
University of Edinburgh researchers have engineered Escherichia coli bacteria to convert polyethylene terephthalate (PET) plastic waste into the common painkiller paracetamol with a 92% conversion...
New Biomarkers Predict Preeclampsia and Gestational Diabetes Long Before Symptoms
Novel prenatal blood tests unveiled at the European Society of Human Reproduction and Embryology (ESHRE) reveal predictive biomarkers that identify preeclampsia and gestational diabetes mellitus...
Longevity Advocate Jim O’Neill Joins US HHS Leadership
Jim O’Neill, a noted figure in longevity research circles with ties to influencers like Bryan Johnson and Peter Thiel, has been appointed deputy secretary at the US Department of Health and Human...
Groundbreaking Immune Insights from First Pig-to-Human Kidney Transplants
An international research consortium presented novel findings at the European Society for Organ Transplantation (ESOT) 2025 on immune responses following pig-to-human kidney xenotransplantation....
AI Matches Doctors in Lung Tumor Mapping for Radiation Therapy
A recent breakthrough demonstrates that advanced AI algorithms can accurately delineate lung tumor boundaries critical for precision radiation therapy with efficacy rivalling expert oncologists....
New Study Links Gut Microbiome Imbalance to Miscarriage Risk in PCOS Women
Presented at the ESHRE annual meeting, research from Paris identifies distinct alterations of gut microbiota and amino acid metabolism associated with increased miscarriage risk in women suffering...
Plastic Waste Turned to Paracetamol Using Engineered Bacteria
Researchers at the University of Edinburgh demonstrated a novel biotechnological method to convert plastic waste into paracetamol, a widely used painkiller. By combining synthetic chemistry and...
Accelerating Oncology Drug Development via CRO-CDMO Integration
A joint study by Thermo Fisher Scientific and Tufts Center for the Study of Drug Development revealed that integrating contract development and manufacturing organizations (CDMOs) with contract...
FDA Internal Discord and Regulatory Challenges in Rare and Neuromuscular Diseases
Insider reports reveal that the FDA commissioner allegedly pushed against KalVista Pharmaceuticals’ rare disease drug approval, coinciding with the agency's investigation of Sarepta's Duchenne...
New Insights in Pig-to-Human Kidney Transplantation Immunity
An international research collaboration revealed crucial immune mechanisms following pig-to-human kidney xenotransplantation, illuminating pathways of cellular response that govern graft...
Emerging Biomarkers and Risk Factors in Maternal and Fertility Health
Multiple studies presented at the European Society of Human Reproduction and Embryology (ESHRE) meeting revealed novel biomarkers and risk factors affecting pregnancy outcomes. Research identified...
Prenatal and Early-Life Factors Driving Chronic Respiratory Disorders
Groundbreaking work published in Pediatric Research detailed how antenatal inflammation contributes to late pulmonary hypertension in bronchopulmonary dysplasia (BPD), highlighting early...
Novel Microbial Pigments and Sustainable Biotechnology Frontiers
Anaerobic bacteria have been discovered to produce a new class of pigments, celluxanthenes, expanding the scope of microbial-derived compounds with potential applications in bioenergy and...
Early Detection and Risk Factors in Metabolic and Gestational Conditions
Recent studies unveiled crucial environmental and lifestyle contributors to metabolic health. Research correlated prenatal chemical and psychosocial exposures with increased gestational diabetes...
Physical Activity Benefits in Parkinson’s Disease Motor Function
A pilot study published in npj Parkinson’s Disease demonstrated that increased physical activity significantly enhances motor function in Parkinson’s patients. The findings suggest that targeted...
Biotech Investment Outlook Amid Market Uncertainty
Jessica Owens, co-founder of Initiate Ventures and former Grail executive, expressed cautious optimism for life science venture capital despite current market volatility. Speaking at Aspen Ideas:...
Prenatal and Reproductive Health Risks Unveiled
Recent studies presented at the 41st Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) highlight significant prenatal and reproductive health risks linked to...
Gut Microbiota and Miscarriage Risk in PCOS
New research presented at ESHRE reveals a compelling link between polycystic ovary syndrome (PCOS), imbalanced gut microbiota, and altered amino acid metabolism associated with increased...