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Advances in Gene Therapy and Cell Engineering for Rare Diseases and Cancer
Novel gene editing and cell therapy approaches are advancing treatment for rare diseases and oncology. Researchers developed a universal cDNA insertion strategy via gene editing for chronic...
Innovations in Energy Storage Materials and Battery Technologies
Researchers continue to push the boundaries of energy storage with cutting-edge materials innovations. Developments include a quasi-solid electrolyte, 3D-SLISE, that enhances lithium-ion battery...
Breakthroughs in Clinical and Diagnostic Technologies
Significant strides in clinical diagnostics and patient monitoring have been reported. Ultrasound AI technologies advance prediction of delivery timing, while a new AI-powered wearable system,...
Environmental and Agricultural Sustainability Innovations
Researchers are pioneering sustainable approaches in agriculture and environmental conservation. Expanded policies incentivize low-carbon biofuel crop practices to aid agricultural...
Bayer-Kumquat Cancer Collaboration Targets KRAS Mutation
Bayer and Kumquat Biosciences have launched a global collaboration worth up to $1.3 billion to develop and commercialize Kumquat’s KRAS G12D inhibitor, a promising treatment targeting a mutation...
Insmed Launches First DPP1 Inhibitor for Lung Disease
Insmed has secured FDA approval for Brinsupri (brensocatib), the first dipeptidyl peptidase 1 inhibitor indicated for treating non-cystic fibrosis bronchiectasis (NCFB), a chronic lung condition...
Sarepta Therapeutics Sells Arrowhead Shares amid Financial Moves
Sarepta Therapeutics is divesting its stake in Arrowhead Pharmaceuticals in two tranches to manage milestone payments and extend its cash runway. The sale will help cover a milestone payment and...
AI Advances in Drug Discovery and Design
Researchers are leveraging AI to push boundaries in drug discovery, including MIT’s use of generative AI to develop compounds targeting drug-resistant bacteria such as MRSA and Neisseria...
Breakthroughs in Brain-Computer Interfaces Enable Inner Speech Communication
Cutting-edge neural prosthetics have advanced to decode inner speech, enabling individuals with severe speech impairments to communicate by thinking their intended sentences. This system builds...
Regulatory Shifts and Policy in US Biotech and Pharmaceutical Sector
The US biotech and pharmaceutical landscape faces significant regulatory changes and political pressures. An executive order from the Trump administration aims to increase domestic pharmaceutical...
Clinical Advances in Cancer and Immunotherapy
Recent clinical research reveals promising advances as well as challenges in oncology. A Phase 1 trial injecting a modified antibody directly into tumors showed promising responses in metastatic...
Innovations in Energy Storage and Battery Technology
Advances in battery materials and manufacturing continue to accelerate, addressing safety, efficiency, and environmental sustainability. New developments include a quasi-solid electrolyte...
Genomic and Molecular Insights in Disease and Development
Cutting-edge genomic research continues to illuminate mechanisms underlying human health and disease. Work on human-accelerated regions (HARs) demonstrates their influence on neural development...
Bayer-Kumquat Deal Targets KRAS G12D Oncology Mutation
Bayer AG has entered a $1.3 billion global collaboration with Kumquat Biosciences to develop and commercialize a KRAS G12D inhibitor, focusing on pancreatic, colorectal, and lung cancers. The KRAS...
Insmed Wins FDA Nod for Brinsupri in Lung Disease
Insmed received FDA approval for Brinsupri (brensocatib), the first therapy approved for non-cystic fibrosis bronchiectasis (NCFB), a progressive lung disease impacting approximately 500,000 U.S....
AI-Driven Peptide Design Targets Undruggable Proteins
Researchers from the University of Pennsylvania and collaborators introduced PepMLM, an AI model leveraging masked language modeling to design peptide binders using only protein sequence data,...
Sarepta Discloses Safety Data, Sells Arrowhead Stock to Extend Runway
Sarepta Therapeutics released detailed safety outcomes for its Duchenne muscular dystrophy gene therapy Elevidys, affirming a positive benefit-risk profile in ambulatory patients with zero acute...
Schrödinger Halts CDC7 Inhibitor Program After Patient Deaths
Schrödinger discontinued development of its CDC7 inhibitor SGR-2921 following the deaths of two acute myeloid leukemia patients in a phase 1 trial, with one death linked to the therapy due to...
10x Genomics Acquires Scale Bio to Expand Single-Cell Sequencing Capacity
10x Genomics acquired Scale Bio for $30 million in cash plus milestones, integrating combinatorial indexing technology with its Chromium platform to enable ultra-high-throughput single-cell...
Groundbreaking AI Combines Genome Editing with Predictive Repair Templates
A University of Zurich-led team developed 'Pythia', an AI tool for designing microhomology-based DNA repair templates that achieve highly precise and predictable CRISPR/Cas9 genome integrations....