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Regeneron’s Garetosmab Cuts Bone Lesions in Rare Disease – FDA Submission Planned
Regeneron Pharmaceuticals reported positive phase III results for garetosmab, a fully human monoclonal antibody targeting activin A, showing significant reduction of new bone growth lesions in...
Eli Lilly’s Oral GLP-1 Pill Outperforms Novo’s Rybelsus in Diabetes Trial
Eli Lilly’s investigational oral GLP-1 receptor agonist, orforglipron, demonstrated superiority to Novo Nordisk’s Rybelsus in a head-to-head Phase 3 trial involving diabetes patients. Orforglipron...
AI Models Generate Functional Bacteriophage Genomes To Fight Drug Resistance
Researchers at Stanford and the Arc Institute have pioneered generative AI models capable of designing complete bacteriophage genomes, advancing beyond single-gene engineering to whole viral...
ArsenalBio Slashes Workforce by Half Amid Strategic Pivot
Arsenal Biosciences, a clinical-stage cell therapy startup noted for its substantial fundraising efforts including a $325 million Series C, has announced a reduction of 50% of its workforce. The...
US COVID Vaccine Policy in Flux amid CDC Leadership Controversy
The US Centers for Disease Control and Prevention is experiencing turmoil following the removal of its director Susan Monarez amid conflicts with Health Secretary Robert F. Kennedy Jr. Kennedy’s...
US Biopharma Giant GSK Commits $30 Billion to Expand US Footprint
Pharmaceutical leader GSK has announced a $30 billion investment plan over five years targeting manufacturing and research and development infrastructure across the United States. This infusion...
Michigan State Develops Analog Neural Processor for Speech Recognition
Researchers at Michigan State University introduced an innovative analog speech recognition system using Resistive Neural Processing Units (RNPUs) operating efficiently at room temperature. This...
USC Scientists Engineer Advanced Kidney Organoids for Disease Modeling
A team from the Keck School of Medicine at USC reported the creation of complex kidney assembloids that combine nephron and collecting duct organoids. These lab-grown structures, transplanted into...
New CRISPR Prime Editors Cut Genomic Off-Target Effects Significantly
Researchers have engineered advanced prime editing techniques employing newly identified Cas9 variants that substantially minimize unintended genetic alterations during genome editing. This...
Duke University Deploys AI for Clinician Support and Cost Reduction
Duke University Health System is implementing a hybrid AI strategy combining homegrown and commercial tools to ease administrative workloads for nurses and improve patient care efficiency. While...
Regeneron’s Rare Disease Win Drives FDA Filing Plans
Regeneron Pharmaceuticals announced topline success in its phase III Optima trial for garetosmab, a monoclonal antibody targeting fibrodysplasia ossificans progressiva (FOP), a rare skeletal...
AI Designs Complete Genomes to Combat Antibiotic Resistance
Researchers at Stanford University and the Arc Institute have harnessed artificial intelligence to design complete, functional bacteriophage genomes, marking a breakthrough in genome engineering....
Biotech Investment Surges as GSK Commits $30 Billion to U.S.
GlaxoSmithKline (GSK) announced a $30 billion investment plan over five years to expand drug manufacturing, research, and clinical trials in the United States, reinforcing its commitment to its...
Areteia Posts Phase 3 Success in Eosinophilic Asthma
Areteia Therapeutics reported positive phase 3 results for dexpramipexole, an oral small molecule targeting eosinophilic asthma. The Exhale-4 trial met its primary endpoint, demonstrating...
Ollin Biosciences Launches with $100M to Challenge Eye Drug Leaders
Newly launched Ollin Biosciences emerged from stealth with $100 million in venture capital to develop next-generation ophthalmology treatments. Co-founded by former Genentech ophthalmologist Jason...
Advances in Gene Therapy and CRISPR Technologies Accelerate Personalized Medicine
Aldevron, IDT, and partners collaborated with the FDA to rapidly develop and deliver the world’s first personalized mRNA-based CRISPR therapy for a baby with a rare metabolic disorder, completing...
New Diagnostic and Predictive Tools Transform Cancer Detection and Treatment
Innovative technologies from multiple research teams are reshaping cancer diagnostics and therapeutic monitoring. The University of Birmingham developed a urine test detecting bladder cancer via...
Manufacturing and Process Innovations Optimize Biologic and Gene Therapy Production
Industry advances are driving greater efficiency in biologics and viral vector manufacturing. Sanofi demonstrates intensified fed-batch processing with high-density seeding and simplified feeding...
Vaccine Policy Turmoil and CDC Leadership Shakeup Reverberate in Public Health
The U.S. CDC faces unprecedented upheaval as former director Susan Monarez testified that Health and Human Services Secretary Robert F. Kennedy Jr. demanded her to approve vaccine recommendations...
Roivant’s Brepocitinib Hits Phase 3 Target in Rare Dermatomyositis
Roivant and Priovant announced a successful Phase 3 trial for brepocitinib, a TYK2/JAK1 inhibitor, in dermatomyositis. The drug demonstrated significant symptom reduction over placebo in a 52-week...