Latest Biotech News

Merck, Novo, and Novartis are moving deeper into early-stage China partnering, with multiple deals now structured around assets earlier in development than in prior cycles, according to...

Hydrogen sulfide is shown to enhance wheat resistance to stripe rust by activating the autophagy pathway. Researchers report that H2S increases TaATG6c persulfidation, effectively turning on...

A Nature study from TIGEM maps a previously unknown TBK1–ULK1 signaling route that controls TFEB, the master regulator of lysosomal biogenesis and autophagy. The group identifies druggable points...

FDG PET/CT is being combined with clinical and pathology variables to refine relapse risk in MALT lymphoma. Researchers in Wuhan developed a prognostic nomogram that integrates imaging metabolism...

The University of Catania introduces a modular computational framework to rank safer RNA-lipid nanoparticle formulations before any lab testing. The method uses virtual patients, machine learning,...

A two-sequence abbreviated liver MRI protocol shows strong accuracy for detecting tumor return after microwave ablation. Researchers report 87.5% sensitivity and 97.6% specificity for recurrent...

Safety scrutiny around biologic drugs is widening after a signal in FDA records points to hair loss as a potential adverse effect category under closer monitoring. The report frames the...

A phase 2 trial reports strong early outcomes for an intensified targeted-drug approach in early-stage classical Hodgkin lymphoma. A regimen pairing two targeted agents with a reduced chemotherapy...

An oral combination strategy expands treatment options in metastatic breast cancer. Results from the phase 3 evERA study in the New England Journal of Medicine show that adding giredestrant, a...

Encrypted cancer genomics and homomorphic encryption benchmarks are addressing the gap between privacy-preserving computation and practical deployment. A new BMC Bioinformatics benchmark evaluates...

A retrospective Chinese study reports that adding the PD-1 inhibitor tislelizumab to paclitaxel–carboplatin and bevacizumab significantly improved response rates and survival in patients with...

A new preclinical study in BMC Medicine reports that intranasally delivered recombinant BMP2/6 proteins delayed dopaminergic neuron degeneration and improved motor function in mouse models of...

Two separate hematology and oncology signals highlight rapid momentum in late-stage and early clinical development. First, a report on a leukemia program describes how recent phase 3 data for the...

A landmark clinical trial reports that a breath-based test detected lung cancer with over 90% accuracy, aiming to address the persistent gap between symptom onset and diagnosis. With lung cancer...

A multicenter study of 167 lung cancer patients found that persistent emotional distress across neoadjuvant therapy and surgery was independently associated with worse overall and progression-free...

Researchers report that engineered exosomes can deliver regenerative cargo directly to neural stem cells after spinal cord injury, aiming to improve functional repair in a setting defined by...

A rat study reports that gene silencing of complement C3 using GalNAc-targeted siRNA nearly eliminated plasma complement, preserved acetylcholine receptor levels, and reduced muscle weakness in a...

The NIH awarded UTHealth Houston researchers a five-year $4 million grant to study why weight returns after discontinuation of GLP-1 receptor agonists. The project is led by Absalon J. Pineda and...

Researchers report that a miniaturized semi-perfusion clone screening method and a multi-parameter manufacturability index can improve clone ranking consistency across scales compared with...

The FDA said it plans to include aging and longevity among the topics highlighted in an upcoming update to its Focus Areas of Regulatory Science (FARS) report. FDA Chief Scientist Steven Kozlowski...