Get the Daily Brief
Latest Biotech News
Pearl Meister Greengard Prize Awarded to Maria Jasin for DNA Repair Research
Maria Jasin, a renowned developmental biologist, has been awarded the 2025 Pearl Meister Greengard Prize by Rockefeller University. Her pioneering research on DNA repair mechanisms has...
Semaglutide Dose Escalation Demonstrated Safe Weight Loss Efficacy
New Phase 3 clinical trials confirm that increasing weekly doses of semaglutide to 7.2 mg significantly enhances weight loss and metabolic health benefits in adults with obesity, with or without...
AI Algorithm Predicts Cardiovascular Risk Using Mammograms and Age
A novel artificial intelligence algorithm trained on routine mammogram images combined with patient age demonstrates predictive accuracy for major cardiovascular disease risk comparable to leading...
BIO Highlights Rapid Growth of Texas Biotech Sector in Industry Visit
The Biotechnology Innovation Organization (BIO) conducted a visit to Texas to spotlight the state’s booming biotech ecosystem, which currently provides over 129,000 jobs and generates $95 billion...
Maze Therapeutics Advances MZE782 With $150M Raise After Positive Phase 1 Data
Maze Therapeutics reported promising Phase 1 clinical trial results for its drug candidate MZE782, targeting metabolic disorders including phenylketonuria and chronic kidney disease. The company...
Novo Nordisk Plans 9,000 Layoffs Amid Competition and Market Challenges
Novo Nordisk announced a major restructuring involving approximately 9,000 job cuts, about 11.5% of its workforce, aiming to streamline management and sharpen focus on expanding diabetes and...
Lila Sciences Nears $300M Series A to Propel Autonomous Science Vision
Lila Sciences, an AI startup focused on building ‘scientific superintelligence,’ is closing in on a Series A funding round of $300 million or more, signaling strong investor interest in leveraging...
PD-L1 siRNA Enhances Immunotherapy by Disrupting Tumor Immune Evasion
Recent research has uncovered that targeted PD-L1 siRNA can effectively enhance cancer immunotherapy outcomes by suppressing tumor defense mechanisms within the immune microenvironment. This novel...
MICrONS Program Unveils Largest Mammalian Brain Wiring Diagram to Date
The Machine Intelligence from Cortical Networks (MICrONS) initiative has delivered the most comprehensive wiring diagram of a mammalian brain, integrating anatomical data with functional neuronal...
Gut Microbiota-Matrix Metalloproteinase-3 Axis Influences Breast Cancer Progression
A novel multi-omics and network pharmacology study has elucidated interactions between gut microbiota metabolites and matrix metalloproteinase-3 (MMP-3) in breast cancer progression. Researchers...
AI Model ACP-EPC Integrates Protein Language and Multi-View Features for Anticancer Peptide Prediction
Lv, Li, and Wang developed ACP-EPC, an interpretable deep learning framework that combines a pre-trained protein language model with multi-view feature extraction to accurately predict anticancer...
Brivaracetam’s Safety Profile in Asian Adults With Focal-Onset Seizures Clarified
A recent study led by Usui et al. assessed the adverse event profile of brivaracetam as adjunctive therapy for focal-onset seizures in Asian adult patients. The research provides critical safety...
Preoperative BMI Significantly Affects Outcomes Following Cardiac Surgery for Infective Endocarditis
A multicenter study involving 4,801 patients has revealed that preoperative body mass index (BMI) plays a critical role in postoperative outcomes for individuals undergoing cardiac surgery due to...
Advances in Precision Liver Transplantation for Hepatocellular Carcinoma via Genomics
Researchers Tian, Wang, and Lu highlighted how third-generation sequencing technologies improve liver transplantation strategies for hepatocellular carcinoma (HCC). Their study emphasizes...
NIH Funding Freeze Disrupts Pediatric Brain Cancer Research
The newly inaugurated administration ordered the National Institutes of Health (NIH) to halt all review meetings for grant applications, critically delaying funding decisions for ongoing cancer...
Maze Therapeutics Advances Metabolic Disorder Pipeline After $150M Raise
Maze Therapeutics announced positive Phase 1 clinical results for its drug candidate MZE782 targeting metabolic disorders including phenylketonuria and chronic kidney disease. Following these...
CMS Fee Schedule Sparks Industry Concern Over Value-Based Care Impact
Major healthcare industry groups, including MGMA, NAACOS, and Premier, issued warnings regarding the Centers for Medicare & Medicaid Services' (CMS) proposed 2026 physician fee schedule. The...
Novo Nordisk’s 9,000 Layoffs Signal Restructuring Amid Market Challenges
Novo Nordisk announced plans to cut approximately 9,000 employees as part of a major restructuring to sharpen commercial focus and reallocate resources towards growth areas in diabetes and obesity...
Penguin Ai Secures $30M for AI-driven Healthcare Back Office Automation
Penguin Ai raised nearly $30 million to develop its artificial intelligence platform aimed at streamlining administrative healthcare processes such as prior authorizations, medical coding, and...
Biosimilar Adoption Challenges Threaten Future Market Savings
Despite biosimilars generating $467 billion in healthcare savings since 2015—and $56.2 billion in the past year—adoption remains uneven across therapeutic areas. A report highlights obstacles...