Claret Bioscience struck a copromotion deal with New England Biolabs to combine Claret’s SRSLY MethylPlus library prep approach with NEBNext EM-seq v2 Conversion Module chemistry for DNA methylation and fragmentation analysis. The workflow is intended to support whole-genome methylation and fragmentomics, including cfDNA applications. The arrangement brings together a library prep method optimized for methylation profiling with an enzyme-based conversion approach for identifying 5mC and 5hmC, enabling broader epigenomics and targeted methylation use cases. Claret Bioscience said the integrated workflow is designed to be compatible with multiple conversion pathways. For liquid-biopsy and epigenetics platforms, the practical impact is tighter integration of sample prep and chemistry that can reduce friction between lab workflows and improve consistency across studies. The financial and commercial terms were not disclosed, but the partnership suggests continued consolidation of tools around end-to-end epigenomic profiling for translational and clinical research.