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New Chemical Staples Stabilize Collagen Integrity at Body Temperature
Researchers at Simon Fraser University identified cysteine residues serving as chemical 'staples' critical for the stability of type IV collagen at physiological temperatures despite its inherent...
FDA Removes Safety Restrictions on CAR T Therapies – Boosting Community Access
The FDA has eliminated the Risk Evaluation and Mitigation Strategies (REMS) for six CAR T cell therapies targeting BCMA and CD19 antigens, including products by Bristol Myers Squibb, Johnson &...
CRISPR Deletes Extra Chromosome to Reverse Down Syndrome in Cells
Japanese researchers at Mie University achieved a pioneering feat by using CRISPR-Cas9 to selectively remove the extra chromosome 21 responsible for Down syndrome in cultured human cells. This...
New AI Model Enhances Pathologist Accuracy in Skin Cancer Diagnoses
A collaborative study led by Karolinska Institutet and Yale University demonstrates that artificial intelligence significantly improves pathologists’ accuracy and consistency in assessing...
Innovative Plasma Method Enables Sustainable Ammonia Production
Scientists at the University of Sydney have developed a plasma-driven process to produce ammonia directly from air, offering a carbon-neutral alternative to the conventional Haber-Bosch method....
Novel Liquid Biopsy Biomarkers Predict Peritoneal Spread in Gastric Cancer
Researchers have identified plasma microRNAs miR-9 and miR-106a as significant indicators associated with peritoneal carcinomatosis in gastric cancer patients. This non-invasive biomarker panel,...
Synthetic DNA Nanoparticles Open New Frontiers in Gene Therapy
Dr. Divita Mathur at Case Western Reserve University secured an NSF CAREER grant to develop synthetic DNA nanoparticles with enhanced cellular uptake and intracellular dynamics. This innovative...
FDA Approval Positions Dizal’s Lung Cancer Drug Against J&J’s Rybrevant
Dizal Pharmaceutical received FDA approval for Zegfrovy, a treatment targeting a rare genetic subtype of non-small cell lung cancer. Positioned as a competitor to Johnson & Johnson’s Rybrevant,...
Discovering Gut Bacteria that May Bind PFAS Toxic ‘Forever Chemicals’
A team led by University of Cambridge researchers identified nine strains of gut bacteria capable of accumulating significant amounts of perfluoroalkyl substances (PFAS), ubiquitous environmental...
Nano-Structured Sheets Protect Against Radiation-Induced Mucositis
Researchers have engineered nanostructured organic sheets that effectively sequester extracellular vesicles and reactive oxygen species generated during radiation therapy, offering protective...
Spatial Biology Tools Illuminate Tumor Microenvironment Complexity
Cutting-edge spatial multiomics technologies integrating protein and gene expression mapping, combined with AI-driven analysis, are revolutionizing cancer research by revealing the intricate...
CRISPR Breakthrough Removes Extra Chromosome in Down Syndrome Cells
Researchers in Japan have demonstrated a pioneering use of CRISPR-Cas9 technology to remove the trisomy 21 chromosome responsible for Down syndrome in lab-grown human cells. This allele-specific...
FDA Removes REMS Restrictions for CAR-T Therapies to Boost Access
The FDA has discontinued Risk Evaluation and Mitigation Strategies (REMS) for six CAR-T cell therapies targeting BCMA and CD19, used in multiple myeloma, leukemia, and lymphoma. This decision...
Dizal’s Sunvozertinib Gains FDA Accelerated Approval in NSCLC
Dizal Pharmaceutical obtained accelerated FDA approval for sunvozertinib (Zegfrovy) to treat adults with locally advanced or metastatic non-small cell lung cancer harboring EGFR exon 20 insertion...
New Diagnostic Advances in Cancer and Neurological Diseases
Novel molecular biomarkers and approaches are emerging to enhance diagnostics and prognostics across oncology and neurology. Studies identify plasma microRNAs linked to peritoneal carcinomatosis...
Advances in Stem Cell and Regenerative Medicine Technologies
Innovative engineering of stem cell sheets with aligned cellular structures enhances protein secretion, bolstering regenerative therapies for chronic and acute conditions. Studies also report...
AI and Digital Tools Expand Healthcare Diagnostics and Research
Artificial intelligence integration significantly enhances diagnostic accuracy and adoption of novel technologies in medical practice. AI-assisted assessment improves pathologists’ interpretations...
Climate Change Impacts and Environmental Biotechnology Developments
Recent research highlights the multifaceted influence of climate change on health, ecosystems, and technology development. Studies explore the effects of global warming on infectious disease...
Innovations in Cancer Therapy and Tumor Microenvironment Modulation
Cutting-edge research unravels complex mechanisms driving tumor progression and unveils novel therapeutic targets. Investigations reveal a transcription factor regulating bladder cancer via...
Biopharma Financing and Industry Market Trends
The biotech sector displays mixed financial activity with notable fundraising rounds and stock index rebounds after earlier declines. Field Medical secured $35 million in Series B venture capital...