10x Genomics joined Roche Sequencing Solutions and Prognosys Biosciences to file two federal lawsuits accusing Illumina of infringing nine patents tied to spatial transcriptomics and single‑cell sequencing. The plaintiffs seek damages, a permanent injunction and fees, and allege Illumina’s recent spatial and single‑cell product introductions violate their licensed intellectual property. Illumina contested the claims and said it will vigorously defend itself. The litigation escalates a pattern of high‑stakes patent battles in sequencing and spatial biology that could reshape competitive dynamics and licensing terms across the market.