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10x Genomics and A*STAR launch large-scale cancer spatial biology study
10x Genomics and Singapore’s A*STAR Genome Institute have initiated the TISHUMAP project, aiming to analyze over 2,500 tumor tissue samples with high-resolution spatial transcriptomics. Utilizing...
India-based AI startup Biotx AI advances GWAS-based drug discovery platform
Biotx AI, a German biotech informatics company with a global reach, leverages large-scale genome-wide association study (GWAS) and phenotypic data to inform drug target identification and...
Sarepta’s gene therapy Elevidys faces FDA black box warning, market restrictions
Following two reported deaths linked to Elevidys, its approved gene therapy for Duchenne muscular dystrophy, Sarepta Therapeutics has agreed to a black box warning on the drug’s label addressing...
U.K. government outlines ambitious plan to boost life sciences sector
The United Kingdom has unveiled a comprehensive life sciences strategy focused on boosting investment, accelerating clinical trials, and enhancing data access over a ten-year horizon. Key goals...
Sarepta restructures amid DMD gene therapy safety concerns
Sarepta Therapeutics announced a strategic restructuring plan involving a 36% workforce reduction of approximately 500 employees, following safety concerns associated with its gene therapy...
CareDx shares plummet on proposed transplant test coverage limits
Shares of CareDx fell sharply following a proposed local coverage determination (LCD) by Medicare contractor Palmetto's MolDx program that would restrict the number of surveillance tests covered...
Chemify launches world’s largest AI-robotics molecular synthesis lab
Chemify has opened its first fully automated 'Chemifarm' near the University of Glasgow, combining AI-driven molecular design with industrial-scale robotic synthesis to accelerate drug discovery...
Thermo Fisher to acquire Sanofi’s Ridgefield sterile manufacturing site
Thermo Fisher Scientific has agreed to acquire Sanofi's sterilized fill-finish and packaging facility in Ridgefield, New Jersey, employing over 200 staff who will join Thermo Fisher post-closing...
A*STAR and 10x Genomics launch large spatial biology cancer study
Singapore's A*STAR Genome Institute of Singapore (GIS) and 10x Genomics have initiated the TISHUMAP project to analyze over 2,000 clinical samples using high-resolution spatial transcriptomics...
FDA advisory committee votes against GSK’s Blenrep in multiple myeloma
The FDA’s Oncologic Drugs Advisory Committee voted against endorsing GSK’s Blenrep (belantamab mafodotin) for second-line treatment of multiple myeloma, citing concerns over benefit-risk balance....
Breakthrough mitochondrial donation technique yields healthy births
Newcastle University researchers have reported eight healthy babies born in the UK through mitochondrial donation and pronuclear transfer technology, aimed at preventing maternally inherited...
Johnson & Johnson exceeds $15B in quarterly innovative medicines sales
Johnson & Johnson reported a strong second-quarter performance, with pharmaceutical sales surpassing $15 billion for the first time. The medical devices segment also contributed significantly to...
Biotech venture funding declines in first half of 2025
Biotech venture capital funding slowed markedly in the first half of 2025, as reported by HSBC and BioCentury analyses. Total venture funds raised dropped to approximately $12.7 billion from $16.9...
Medicare Coverage Tightens on Molecular and Transplant Diagnostics
Medicare contractor Palmetto GBA proposed local coverage determinations (LCDs) that impose stricter requirements on molecular diagnostics for ductal carcinoma in situ (DCIS) and transplant...
Sarepta Therapeutics Restructures Amid DMD Therapy Challenges
Sarepta Therapeutics announced a significant workforce reduction, cutting approximately 36% of staff, alongside a strategic pivot from gene therapies to siRNA platforms focused on rare genetic...
UK and Singapore Lead Groundbreaking Mitochondrial IVF Trials
Researchers in the UK reported the successful births of eight healthy children following mitochondrial donation procedures, which involve transferring nuclear DNA from eggs of women with...
Biotech Venture Funding Slows and Market Dynamics Shift
Biotech venture capital funding and initial financing rounds notably declined in the first half of 2025, as highlighted by HSBC and industry analyses, erasing the early-year momentum....
FDA Advisory Committee Voices Concern Over GSK's Blenrep for Multiple Myeloma
The FDA's Oncologic Drugs Advisory Committee voted against GlaxoSmithKline's Blenrep for multiple myeloma, citing unfavorable benefit-risk considerations. High rates of ocular toxicities including...
Johnson & Johnson Reports Strong Q2 Led by Med-Tech and Innovative Medicines
Johnson & Johnson beat expectations in its second-quarter earnings, driven by an $8.54 billion medical device segment showing robust growth, especially in cardiology with over 22% rise. Innovative...
FDA Funds and Regulatory Shifts Impact Biotech Innovation Landscape
Recent actions from the FDA and NIH, including significant staff departures at FDA’s drug center and multiple funding cuts from NIH, have introduced uncertainties in the biotech research and...