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Newborn Genome Sequencing Project in France Advances Rare Disease Detection
The Perigenomed project in France is exploring the feasibility of routine genome sequencing as part of newborn screening. With 500 babies sequenced to date and expansion plans to sequence 2,500...
Johnson & Johnson Beats Q2 Expectations Driven by Medical Devices and Pharma
Johnson & Johnson reported a strong second quarter with sales surpassing $23.7 billion, driven by medical devices which grew over 8% and pharmaceuticals exceeding $15 billion in revenue. The...
New Techniques Illuminate Brain Function and Cancer Mechanisms
Scientists are making significant strides in mapping brain activity and cellular behaviors. Harvard and Broad Institute teams identified endothelial connexin clusters critical for propagating...
Sarepta restructures amid gene therapy safety concerns and black box warning
Sarepta Therapeutics has initiated a significant restructuring after safety issues emerged with its Duchenne muscular dystrophy gene therapy Elevidys, including two patient deaths from acute liver...
Mitochondrial donation trial reports eight healthy births in UK
Researchers in the UK reported the birth of eight healthy babies following mitochondrial donation and pronuclear transfer, a technique involving DNA from three people to prevent mitochondrial...
FDA and regulatory updates challenge drug approvals and market entries
The Food and Drug Administration has recently raised questions and regulatory hurdles for several drugs. The FDA questioned the efficacy of Otsuka's Rexulti combination for PTSD, requesting more...
New advances in understanding and targeting neurodegenerative diseases
Significant progress has been made in neurodegenerative disease research through proteomics, genetics, and novel therapies. The Global Neurodegeneration Proteomics Consortium released one of the...
AI and computational tools empower drug discovery and process optimization
Artificial intelligence and advanced computational platforms are increasingly transforming drug discovery and biomanufacturing. Biotx AI, a German startup, enhances genome-wide association data...
Innovations in pain, inflammation, and chronic disease biology
New biological insights into pain, inflammation, and chronic disease are emerging. Researchers identified a protein selectively regulating chronic inflammation without affecting acute inflammatory...
Biotech venture financing dynamics and major deals in 2025
Biotech venture financing showed signs of slowdown in the first half of 2025, with total funds raised falling to $12.7 billion compared to $16.9 billion in the prior year period. Deal values and...
Plant biology and agriculture innovations leveraging genomics and technology
Emerging research in plant biology and agriculture integrates genomic and technological advances to improve crop yield, sustainability, and adaptation. Studies clarified distinctions between...
Molecular and cellular biology insights enable therapeutic advances
Recent molecular and cellular biology studies unveiled mechanisms and targets with therapeutic potential. Scientists revealed a liquid-like protective coating on mitotic chromosomes to prevent DNA...
Corporate and industry leadership, acquisitions, and strategic deals
Key corporate developments and strategic deals marked the biotech and pharma landscape. Bayer extended CEO Bill Anderson's contract through March 2029 to continue transformation efforts. Sino...
Sarepta Therapeutics Restructures Amid DMD Therapy Safety Concerns
Sarepta Therapeutics announced a major restructuring, cutting approximately 36% of its workforce—about 500 jobs—following the deaths of two Duchenne muscular dystrophy (DMD) patients treated with...
Mitochondrial Donation Yields Healthy Babies with Three-Person DNA Technique
Researchers in the UK have reported the birth of eight healthy babies born using mitochondrial donation, an IVF technique involving DNA from three individuals—two parents and a mitochondrial...
GLP-1/GIP Dual Agonist Shows Promising Weight Loss in China Phase III Trial
A joint development by Jiangsu Hengrui Pharmaceuticals and Kailera Therapeutics of a once-weekly injectable dual GLP-1/GIP receptor agonist demonstrated significant weight loss of approximately...
FDA Reviews Safety and Efficacy Concerns for GSK’s Blenrep in Multiple Myeloma
Ahead of the July 17 advisory committee meeting, the FDA raised concerns about the ocular toxicity profile and dose optimization of GSK's antibody-drug conjugate Blenrep for relapsed or refractory...
Advanced Mapping Reveals Brain Blood-Flow Regulation via Endothelial Connexins
New research from Harvard Medical School and collaborators uncovered that specific endothelial gap junction proteins, connexins Cx37 and Cx40, enable rapid communication along brain blood vessels,...
Innovative Molecular and AI Platforms Accelerate Drug Discovery and Biomanufacturing
Dalriada announced a strategic collaboration with a public computational company to apply its iCLASS proteomics platform combined with computational technologies for novel drug discovery....
Biopharma Dealmaking Remains Strong with Multiple High-Value Transactions
Biopharma deal value surged past $138 billion in the first half of 2025, fueled by large transactions including Sino Biopharmaceutical’s acquisition of LaNova Medicines for up to $951 million and...