Get the Daily Brief
Latest Biotech News
Isomorphic Labs unveils IsoDDE: proprietary AI ignites debate
Isomorphic Labs published a technical report describing IsoDDE, a proprietary drug‑discovery engine the company says advances protein–drug and antibody interaction predictions. Scientists quoted...
Korsana raises $175M: brain‑penetrant antibody platform draws capital
Korsana Biosciences closed a $175 million financing to advance a preclinical Alzheimer’s program built on a platform designed to ferry antibodies across the blood‑brain barrier. The company says...
Messy LNPs deliver better: single‑particle study flips design rules
A University of Copenhagen team presented single‑particle analyses showing that disordered lipid nanoparticles (LNPs) release RNA cargo inside cells more effectively than highly organized...
Forbion and Sanofi back Altesa with $75M: vapendavir Phase IIb set to start
Forbion led a $75 million Series B financing for Altesa BioSciences, with participation from Sanofi and existing investors, to fund the Phase IIb CARDINAL study of vapendavir — an oral antiviral...
MoonLake posts mid‑stage arthritis win: confidence ahead of FDA filing
MoonLake Immunotherapeutics disclosed Phase 2 data showing a clinically meaningful benefit for its investigational therapy in an aggressive inflammatory arthritis population, information the...
Illuminare‑1 lights nerves in humans: Phase 1 shows rapid, sustained visualization
Illuminare Biotechnologies reported first‑in‑human Phase 1 data for Illuminare‑1, a fluorescent imaging agent that binds myelin to visualize peripheral nerves under blue light. The trial showed...
Electrical readouts for organoids: new probes aim to cut late‑stage failures
Diagnostic Biochips unveiled a neural probe technology intended to add functional electrophysiological readouts to organoid screening, with the goal of improving early‑stage predictive validity...
EANM launches award to accelerate alpha‑RLT research for prostate cancer
The European Association of Nuclear Medicine unveiled the 2026 EANM Young Scientist Network Award, funded by Advanced Accelerator Applications (Novartis), to accelerate research in alpha...
Korsana Biosciences Raises $175M – Brain‑penetrant Alzheimer’s Antibody Push
Korsana Biosciences closed a $175 million financing to advance a preclinical Alzheimer’s program that uses a platform to ferry antibodies across the blood‑brain barrier. The company said the...
FDA Reverses Course: Will Review Moderna’s Seasonal mRNA Flu Shot
The FDA agreed to set aside a recent refuse‑to‑file decision and will review Moderna’s mRNA‑1010 seasonal flu vaccine after a Type A meeting, with a target PDUFA date of August 5. Moderna proposed...
MoonLake Discloses Mid‑Stage Arthritis Win... Confidence Ahead of FDA Filing
MoonLake Immunotherapeutics disclosed Phase 2 data showing a clinically meaningful benefit in an aggressive inflammatory arthritis cohort and said the result increases its confidence ahead of an...
Fluorescent Nerve Agent Shows Early Safety – Phase 1 Signals Rapid Visualization
Illuminare Biotechnologies reported first‑in‑human Phase 1 results for Illuminare‑1, an imaging agent that fluoresces under blue light by binding myelin, showing rapid onset and sustained nerve...
Isomorphic’s IsoDDE Stuns Scientists – Proprietary Drug‑Discovery AI Unveiled
Isomorphic Labs released a technical report on IsoDDE, a proprietary drug‑discovery engine its developers say improves predictions of protein–drug interactions and antibody structures. The company...
Disorganized LNPs Release More mRNA – Single‑Particle Study Shows
New single‑particle analyses presented at the Biophysical Society meeting found that lipid nanoparticles (LNPs) with internal disorder deliver RNA cargo more efficiently into cells than highly...
PDHA1 Drives Ferroptosis Resistance in Prostate Cancer – New Target Emerges
A recent study identified PDHA1 as a mediator of ferroptosis resistance in prostate cancer via upregulation of AIFM2, revealing a potential mechanism by which tumors evade...
Focused Ultrasound Opens Blood‑Brain Barrier Safely – Tight‑junctions Reorganized
Researchers published mechanistic data showing that focused ultrasound transiently and reversibly opens the blood‑brain barrier by reorganizing tight junction proteins, offering a safer delivery...
Intestinal IL‑22 Raises GLP‑1 Levels – Improves Glucose Control in Mice
A Nature Communications study found that intestinal interleukin‑22 increases production of GLP‑1, improving glucose homeostasis in male mice and reversing obesity‑induced insulin resistance....
EANM Launches Award to Accelerate Alpha Radioligand Therapy Research
The European Association of Nuclear Medicine announced the 2026 EANM Young Scientist Network Award, funded by Advanced Accelerator Applications (a Novartis company), to support alpha radioligand...
FDA reopens Moderna’s flu file: PDUFA date set for Aug. 5
The FDA reversed a refusal-to-file decision and agreed to review Moderna’s seasonal flu vaccine mRNA-1010, setting a target PDUFA decision date of August 5. Moderna and CEO Stéphane Bancel...
Korsana secures $175M to push brain-penetrant Alzheimer’s antibodies
Korsana Biosciences closed a $175 million financing to advance a preclinical Alzheimer’s program based on a platform that ferries antibodies across the blood–brain barrier. The company says its...