Latest Biotech News

Cretostimogene grenadenorepvec delivered durable activity in a phase III BOND-003 cohort C trial for high-risk, BCG-unresponsive non–muscle-invasive bladder cancer with carcinoma in situ,...

A new report tied to the Milken Institute highlighted reimbursement friction as a core headwind for women’s health startups, urging early planning for coverage strategy when clinical evidence and...

A study described how prolonged GLP-1 exposure remodels gene expression in pancreatic tissue by switching phosphorylation states that partially reprogram pancreatic beta cells. The research...

A research team reported an open, publicly available tumor organoid biobank that maps gene dependencies across 256 clinically annotated organoids, alongside multi-omics profiling and genome-wide...

Researchers reported in Cell Death Discovery that blocking PHGDH can overcome dabrafenib resistance through metabolic rewiring in BRAF V600E anaplastic thyroid carcinoma. The work centers on...

A study published in colorectal cancer research described a mechanism by which DUSP4 enhances antitumor CD8+ T-cell activity and improves CAR-T performance in mouse models. The authors report...

New preclinical work in nerve-injured mice identified PARP1 as a driver of neuropathic pain through GPX4-dependent ferroptosis in sensory neurons. Researchers led by Y. Guo, L. Huang and Y. Chen...

A new study challenged the assumption that deep-brain stimulation (DBS) benefits movement symptoms but has limited impact on cognition in Parkinson’s disease. Researchers reported that tuning DBS...

Researchers reported an epoxy-engineered lead zirconate titanate (PZT) nanocomposite sensor array designed to detect physiological and swallowing signals in noisy, constantly moving...

A STAT investigation reported details about Commure, a $7 billion Silicon Valley company automating healthcare administrative workflows using AI, including internal referral-compensation...

Cretostimogene grenadenorepvec delivered durable activity in BCG-unresponsive, high-risk non–muscle-invasive bladder cancer with carcinoma in situ, according to results from the international...

Early tests suggest gene-edited beagles may produce no detectable major dog allergen, Can f 1, potentially advancing approaches aimed at reducing dog allergy symptoms. The work described initial...

BMJ Public Health retracted a controversial study that alleged a link between COVID-19 vaccines and excess mortality after an institutional investigation. The decision removes a frequently cited...

Fujifilm Biotechnologies expanded its manufacturing footprint and leaned into FDA’s PreCheck Pilot Program selection, with Holly Springs, North Carolina named among seven facilities chosen to...

Capricor Therapeutics moved to amend its biologics license application for deramiocel, seeking approval to improve limb function in Duchenne muscular dystrophy after the company previously faced a...

A first-line regimen combining sintilimab, IBI305 (a biosimilar version of bevacizumab), and chemotherapy showed promise in advanced gastric and gastroesophageal junction adenocarcinoma, according...

Researchers created a publicly available tumor organoid biobank with multi-omics characterization and gene dependency mapping, aiming to close gaps left by traditional cancer cell lines. The...

Blocking PHGDH overcame dabrafenib resistance in BRAF V600E anaplastic thyroid carcinoma by driving metabolic rewiring, according to findings published in Cell Death Discovery by S.Y. Kim and M.H....

A separate operational update from the CDMO landscape highlighted how contract manufacturers are adding capacity and quality infrastructure while incorporating digital systems for data integrity....

The Hong Kong Polytechnic University (PolyU) reported an AI “Virtual Patient” simulation system that integrates multimodal patient data to personalize cancer monitoring and treatment evaluation....