Scientists at Hebrew University and Believer Meats reported a Nature study demonstrating a non‑genetically modified method to induce stable self‑renewal in bovine cells by activating telomerase and PGC1α. The team created bovine cell lines capable of extended proliferation without oncogenic transformation, addressing a key bottleneck for cultivated beef scale‑up. The method avoids direct genetic modification—potentially easing regulatory and consumer hurdles—and could supply a safe, renewable cell source for cultured meat manufacturing. Researchers emphasized further validation for long‑term stability, differentiation capacity and manufacturing translation.