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Celcuity’s Breast Cancer Drug Tops Phase III — Shares Triple
Minneapolis-based Celcuity reported positive top-line results from its Phase III Viktoria-1 trial evaluating the breast cancer drug gedatolisib. The drug, tested in hormone receptor-positive,...
GSK and Hengrui Pharma Strike $12.5 Billion Deal for COPD Pipeline
GlaxoSmithKline entered a multi-billion-dollar licensing agreement with Jiangsu Hengrui Pharmaceuticals granting GSK rights to a portfolio of 12 drugs, including a promising phase I...
Adaptimmune Sells Cell Therapy Assets Amid Financial Strain
Adaptimmune, facing significant financial challenges, is selling its three cell therapy assets, including the FDA-approved sarcoma drug Tecelra, to US WorldMeds for an upfront payment of $55...
AI Enhances Gene Set Analysis Accuracy Through Database Verification
Researchers at the NIH have developed GeneAgent, an artificial intelligence agent based on large language models that improves the accuracy of gene set analysis by autonomously verifying its...
New DynaTag Method Maps Transcription Factors at Single-Cell Level
Scientists at the University of Cologne introduced DynaTag, a novel technique enabling high-resolution mapping of transcription factor binding sites even in single cells and low-input samples by...
Antimatter Qubits Created, Paving Way for Quantum Computing Advances
Physicists have succeeded in creating the first quantum bit (qubit) using antimatter—specifically a single trapped antiproton—achieving a nearly one-minute spin coherence time. Published in...
Mass Ivermectin Administration Cuts Malaria Transmission in Kenya
A cluster-randomized trial conducted in Kwale, Kenya tested monthly ivermectin administration in children over a three-month period to evaluate its impact on malaria transmission. The study...
Sanofi Leverages AI to Guide Drug Development Decisions
Sanofi’s CEO Paul Hudson disclosed that the company integrates artificial intelligence into its drug development pipeline decision-making processes. AI tools provide dispassionate recommendations...
New Arab Human Pangenome Assembled Using Long-Read Sequencing
A landmark study led by Mohammed Bin Rashid University assembled the first high-quality pangenome reference for Arab populations using PacBio’s HiFi long-read sequencing technology. Analyzing...
FDA Clears Sarepta Duchenne Therapy After Investigation
The FDA has resumed clearance for Sarepta Therapeutics' Elevidys gene therapy targeting ambulatory patients with Duchenne muscular dystrophy after a thorough safety review. This follows a...
Celcuity’s Breast Cancer Therapy Achieves Late-Stage Milestones
Celcuity reported positive phase III results for its breast cancer drug gedatolisib, significantly reducing progression risk in hormone receptor-positive, HER2-negative advanced tumors that were...
Adaptimmune Sells Cell Therapy Assets in Turnaround Effort
Cell therapy developer Adaptimmune announced the sale of its sarcoma therapy Tecelra and two late-stage assets to US WorldMeds for an upfront payment of $55 million, with potential $30 million in...
GSK Inks $12.5B Deal with Hengrui for COPD and More
GlaxoSmithKline has secured rights to 12 drug programs from Jiangsu Hengrui Pharmaceuticals, including the promising phase I COPD candidate HRS-9821, for $500 million upfront and up to $12 billion...
Breakthrough in Arab Human Pangenome Sequencing Posted
Mohammed Bin Rashid University of Medicine and Health Sciences and partners have published the first high-quality Arab human pangenome constructed using PacBio's HiFi long-read sequencing. The...
AI Augments Pharma R&D Decision-Making
Sanofi's CEO Paul Hudson revealed that the company integrates AI recommendations into its drug development decision process, using machine insights to guide progression through clinical phases....
MapLight Raises $373M to Advance CNS Disease Pipeline
MapLight Therapeutics secured a $372.5 million Series D funding round to fuel development of its pipeline candidates for CNS disorders, including schizophrenia and Alzheimer's disease. The...
Optogenetic Platform Enables Precise Molecular Control in Cells
KAIST researchers introduced RELISR, an optogenetic platform offering reversible, spatiotemporal regulation of protein and mRNA storage and release within living cells and animals. Utilizing...
Autophagy Mechanisms Reveal Therapy Pathways for Parkinson’s
University of Vienna scientists elucidated molecular mechanisms underpinning mitophagy initiation via transmembrane cargo receptors BNIP3 and NIX, detailing hierarchical flexibility in autophagy...
Ivermectin Mass Drug Administration Cuts Malaria Transmission
The BOHEMIA trial in Kenya demonstrated a 26% decrease in new malaria infections following mass administration of ivermectin to children aged 5–15. This cluster-randomized study confirms...
Sanofi CEO Endorses AI for Drug Development Decisions
Sanofi's CEO Paul Hudson revealed that the company utilizes artificial intelligence to assist in progressing drug candidates through development phases. The AI system dispassionately recommends...