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CMS rolls out voluntary Medicare model: GLP‑1 coverage expanded
CMS launched a voluntary payment model designed to broaden Medicare coverage of GLP‑1 weight‑loss drugs. The agency announced the model as a step to increase beneficiary access and address drug...
FDA approves Yartemlea: First therapy for stem‑cell transplant complication
The FDA approved Omeros’s complement‑system drug Yartemlea to treat a severe, potentially fatal complication of hematopoietic stem cell transplants, marking the first regulatory clearance for this...
J&J axes eczema drug — $1.25B acquisition deal unwinds
Johnson & Johnson halted development of an experimental eczema therapy it acquired for $1.25 billion, citing efficacy shortfalls in internal testing. The decision ends expectations tied to the...
CAR‑T neurotoxicity studied: new mechanisms identified
Recent research released new insights into neurotoxicity associated with CAR‑T cell therapies. The work maps clinical patterns and potential biological pathways underpinning neurological adverse...
CAR‑T vs bispecifics... head‑to‑head in relapsed B‑cell NHL
A new meta‑analysis compared CAR‑T therapies with bispecific antibodies in relapsed or refractory indolent B‑cell non‑Hodgkin’s lymphoma, synthesizing efficacy and safety across published trials....
Antibodies neutralize Marburg — cross‑reactivity with Ravn identified
Researchers discovered a class of potent antibodies that cross‑neutralize the Marburg virus and the related Ravn virus, reporting results in npj Viruses. The antibodies show broad activity against...
Nanovaccines: engineered approach to hepatocellular carcinoma immunotherapy
Researchers reported engineered nanovaccine platforms aimed at hepatocellular carcinoma (HCC) immunotherapy, describing design features that improve antigen presentation and immune stimulation in...
Smart AAVs respond to tumor microenvironment – precision delivery
A new design framework for adeno‑associated virus (AAV) vectors enables dynamic responses to tumor microenvironment cues, improving tumor targeting and intratumoral delivery in preclinical models....
SpatialBench... agents face real‑world spatial biology test
SpatialBench introduced a benchmark suite of 146 verifiable problems drawn from authentic spatial biology workflows to evaluate agent‑style models on spatial assay analysis. The benchmark spans...
AI prognostics in gastric cancer — models refine risk, therapy selection
Deep learning models developed for gastric cancer prognosis and immunotherapy response prediction showed improved risk stratification using digital pathology. The study, published in the Journal...
CMS unveils voluntary payment model to expand Medicare GLP‑1 access
CMS launched a voluntary payment model designed to expand Medicare coverage of GLP‑1 weight‑loss drugs by testing alternative payment and reimbursement structures for participating plans and...
FDA approves Yartemlea: first therapy for fatal stem‑cell transplant complication
The FDA granted approval to Omeros’s complement inhibitor Yartemlea for treating a severe, potentially fatal complication of hematopoietic stem cell transplants, marking the first approved therapy...
J&J drops eczema asset — $1.25 billion acquisition yields failure
Johnson & Johnson announced it is discontinuing development of the eczema candidate JNJ‑5939 (NM26) acquired in a $1.25 billion deal, after the drug failed to meet efficacy thresholds in a Phase 2...
CAR‑T vs bispecifics... meta‑analysis compares outcomes in relapsed B‑cell NHL
A new meta‑analysis compared CAR‑T therapies with bispecific antibodies for relapsed or refractory indolent B‑cell non‑Hodgkin’s lymphomas, synthesizing outcomes across trials to clarify efficacy...
Potent antibodies target Marburg and Ravn: cross‑neutralizers discovered
Researchers reported discovery of a class of potent, cross‑neutralizing monoclonal antibodies that neutralize the Marburg virus and the related Ravn virus, according to a study published in npj...
Tumor‑responsive AAVs enable precise therapy: smart vectors breach TME
Scientists unveiled an intelligent design framework for adeno‑associated virus (AAV) vectors that dynamically respond to tumor microenvironment cues to improve tumor targeting and intratumoral...
SpatialBench... benchmark for agents on real spatial biology tasks
SpatialBench, introduced in a new paper, offers a suite of 146 verifiable problems drawn from real spatial biology workflows across five platforms (MERFISH, Seeker, Visium, Xenium, ATLASxomics...
Nanovaccines target HCC: new routes for liver cancer immunotherapy
Researchers presented nanovaccine platforms engineered to prime immune responses against hepatocellular carcinoma (HCC), detailing antigen delivery, adjuvant selection and tumor‑site activation...
CAR‑T neurotoxicity... fresh findings on mechanisms and management
A recent report consolidated advances in understanding CAR‑T associated neurotoxicity, outlining cellular and molecular mechanisms implicated in immune effector cell‑associated neurotoxicity...
Targeted protein degradation: therapeutic promise and cross‑species impacts
A broad review examined targeted protein degradation technologies and their implications for human health and non‑human species, mapping therapeutic opportunities and potential ecological or...