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Big Pharma transactions and platform expansion
Merck KGaA agreed to acquire Bio-Techne for about $11.3 billion, the company’s largest deal since its 2015 Sigma-Aldrich acquisition. The cash offer of $73 per share comes with a ~36% premium and...
Biotech M&A restructuring and pipeline slimming
Biogen moved to cut most of its pipeline work after acquiring Apellis Pharmaceuticals for $5.6 billion, pausing or canceling investment across the majority of Apellis programs that came with the...
Financing rounds for prophylactic and platform therapies
RQ Bio secured an oversubscribed $115 million Series A to advance RQB01, a long-acting antibody program intended to provide broad, season-long protection against influenza in high-risk and...
Venture capital fueling late-stage trials in ophthalmology
Ollin Biosciences raised $330 million in a Series B as it prepares pivotal testing for an eye therapy targeting diabetic macular edema and wet age-related macular degeneration. The funding is...
AI-enabled target discovery and next-gen cell therapies
Researchers at the University of Pennsylvania’s Perelman School of Medicine and Abramson Cancer Center used an AI, human-in-the-loop framework to nominate and validate a multi-cancer CAR T target....
Immunology platform collaborations and multi-disease target discovery
Immunai inked a research collaboration with Boehringer Ingelheim valued at up to $15 million to identify novel T-cell targets across oncology and autoimmune disease. The partnership runs through...
Cell/gene therapy pipeline pivots via reverse merger and re-listing
Remix Therapeutics is set to go public via a reverse merger with Passage Bio, a gene therapy company co-founded by Jim Wilson. Under the agreement, the combined entity is expected to close in the...
Precision oncology diagnostics gaining regulatory footing
Natera’s Signatera MRD assay gained regulatory approval in Japan from the Pharmaceuticals and Medical Devices Agency for colorectal cancer use in the neoadjuvant setting. The decision effectively...
FDA and workforce stability as operational priority
At BIO 2026, FDA leadership emphasized workforce stabilization efforts after earlier staffing reductions, detailing plans to hire and retain personnel to reduce operational disruption. FDA acting...
M&A and life-sciences tools consolidation
Merck KGaA agreed to acquire Bio-Techne for about $11.3 billion, a move aimed at expanding the German company’s life-science footprint across multiomics, spatial biology, and advanced research...
FDA approval expands ADC market in first-line TNBC
The FDA expanded Gilead’s Trodelvy label for first-line triple-negative breast cancer, allowing use regardless of PD-L1 status and creating a new competitive front in the TROP2 ADC market. The...
Ionis wins broader FDA label for Tryngolza
Ionis Pharmaceuticals received FDA approval that further expands Tryngolza (olezarsen) for adults with severe hypertriglyceridemia, widening the drug’s commercial address. The approval came after...
CAR T target discovery powered by human-in-the-loop AI
A study in Cell reports an AI-enabled framework for nominating CAR T antigens, with preclinical validation of a lead candidate aimed at multi-cancer potential. Researchers at the University of...
Big pharma builds new AI immune target pipeline with Immuneai
Immune profiling company Immunai entered a research collaboration with Boehringer Ingelheim worth up to $15 million to identify novel T-cell targets across oncology and autoimmune disease. Immunai...
New grant award advances mitochondrial therapy for Parkinson’s
The Michael J. Fox Foundation awarded X-tosis a $2.74 million grant to advance XTS-001 toward clinical development for Parkinson’s disease. The funding will support confirmatory studies, biomarker...
Regulatory IND move for stem-cell therapy in Parkinson’s
Unixell Biotechnology obtained FDA IND clearance for UX-DA003, its allogeneic iPSC-derived therapy for Parkinson’s disease, enabling clinical development in the U.S. The company also reported IND...
U.S. biotech financing: RQ Bio raises for long-acting flu prophylaxis
RQ Bio secured an oversubscribed $115 million Series A to advance RQB01, a long-acting antibody program aimed at preventing seasonal influenza in high-risk and immunocompromised populations. The...
Immunotherapy manufacturing: engineered feeder line boosts NK expansion
Researchers reported an engineered feeder cell line that sharply increases allogeneic NK cell production, addressing a major bottleneck in adoptive cell therapy manufacturing. Using an optimized...
Reverse merger brings Remix out of Passage Bio structure
Remix Therapeutics agreed to go public through a reverse merger with Passage Bio, with the combined company expected to trade under the Remix name and the ticker RMTX. Remix investors are slated...
M&A: Merck KGaA buys Bio-Techne to expand life-science tools and workflows
Merck KGaA agreed to acquire Bio-Techne in an approximately $11.3 billion deal, the company said, positioning the combined platform to span discovery, translational research, and commercial...