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Advances in Energy Storage: Lithium and Zinc Battery Technology Breakthroughs
Researchers in energy storage technologies have achieved notable innovations. Lithium metal batteries receive performance boosts through novel electrolyte designs, improving energy density and...
Breakthroughs in Infectious Disease: Targeting Viruses, Parasites and Antimicrobials
Infectious disease research uncovers novel mechanisms and potential therapies. A new protein therapy emerges as the first-ever antidote for carbon monoxide poisoning. Studies reveal dopamine...
Financial and Industry Moves: Fundraising, Layoffs, and Market Trends
Biotech financing and corporate shifts characterize the current market landscape. Hatteras Venture Partners closed over $200 million across two life sciences funds aimed at early-stage...
Bayer and Kumquat Ink $1.3B KRAS G12D Cancer Drug Deal
Bayer has entered a global exclusive license and collaboration with Kumquat Biosciences to develop and commercialize a KRAS G12D inhibitor, a mutation implicated in 25% of human cancers including...
FDA Approves First Drug for Non-Cystic Fibrosis Bronchiectasis
Insmed received FDA approval for Brinsupri (brensocatib), the first approved treatment for non-cystic fibrosis bronchiectasis (NCFB), a chronic lung disease affecting approximately 500,000 U.S....
AI Advances Precise Genome Editing Using Deep Learning and Microhomology Templates
Researchers at the University of Zurich developed “Pythia,” an AI model that predicts DNA repair outcomes post-CRISPR cutting, enabling the design of microhomology-based DNA repair templates that...
Novel Cancer Immunotherapy Targets Triple-Negative Breast Cancer Resistance
University of Pittsburgh scientists identified lncRNA EPIC1 as a driver of immunotherapy resistance in triple-negative breast cancer (TNBC). EPIC1 suppresses type I interferon responses...
Insmed’s Lung Drug Brinsupri Shows Commercial and Clinical Progress
Insmed’s Brinsupri, a DPP1 inhibitor for bronchiectasis, is poised as a blockbuster following FDA approval and positive clinical trials. The company confirmed plans for dual doses to provide...
AI Models Reveal New Approaches to Drug Discovery and Cancer Treatment
Multiple studies highlight the integration of AI in drug discovery and cancer research. KAIST developed an AI model for autonomous design of drug candidates targeting cancer mutations. Meanwhile,...
Breakthroughs in AI-Enabled Diagnostics and Imaging Transform Healthcare
Cutting-edge AI and deep learning tools are revolutionizing medical diagnostics. New models detect cervical precancer with compact microscopes, enhance ultrasound 3D reconstruction, and improve...
New Therapeutics Target KRAS and Autoimmune Diseases with Phase III Advances
Two significant clinical successes emerged this week: Novartis achieved back-to-back Phase III wins for ianalumab in Sjögren’s disease and primary immune thrombocytopenia, demonstrating promising...
Novel Protein-Based Antidote Shows Promise Against Carbon Monoxide Poisoning
University of Maryland School of Medicine researchers engineered a new protein therapy that rapidly and selectively removes carbon monoxide (CO) from the bloodstream during acute poisoning...
Insmed’s Brensocatib Gains FDA Nod as First Chronic Lung Disease Therapy
Insmed secured FDA approval for Brensocatib (Brinsupri), the first treatment for non-cystic fibrosis bronchiectasis (NCFB). This dipeptidyl peptidase 1 (DPP1) inhibitor targets neutrophilic...
Bayer-Kumquat Team Up on KRAS G12D Inhibitor With $1.3B Potential
Bayer entered an exclusive global license and collaboration agreement with Kumquat Biosciences to develop and commercialize Kumquat’s KRAS G12D inhibitor, a precision oncology asset targeting...
Novartis Clinches Phase III Wins for Autoimmune ianalumab
Novartis announced two positive Phase 3 trial readouts for ianalumab, a monoclonal antibody with dual B-cell depletion and BAFF-R inhibition activities, in Sjögren’s disease and primary immune...
Advances in AI and Multi-Omics Revolutionize Biomarker and Drug Discovery
Cutting-edge artificial intelligence and machine learning applications are accelerating discoveries in cancer biomarker identification and drug combination prediction. Multi-omics integration...
AI-Powered Diagnostics and Imaging Technologies Make Strides
Recent breakthroughs in AI-enhanced diagnostic tools include AI-assisted compact microscopes for cervical precancer screening, AI-enhanced 3D ultrasound imaging for improved resolution, and AI...
Insilico and University Teams Advance Small Enzymes and Gene Editing
Researchers have developed novel AI-based methods to design small enzymes tailored for bioprocessing and pioneered AI-assisted gene editing precision. ProtGPT2, a language model for proteins,...
Emerging Respiratory and Neurodegenerative Therapies Show Promise
Novel therapeutics targeting respiratory and neurodegenerative diseases have gained momentum. Insmed’s first DPP1 inhibitor brensocatib offers a new option for bronchiectasis patients. Meanwhile,...
FDA Regulatory Reforms and Leadership Shakeup Influence Industry
Significant regulatory shifts are underway at the FDA. Vinay Prasad was swiftly reinstated as director of CBER following political controversies, reflecting agency leadership volatility....