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Novel Approaches in Ophthalmology and Vision Therapy
Innovations in eye disease diagnostics and treatment are advancing. KAIST researchers have developed a wireless OLED contact lens for enhanced retinal diagnostics, offering new avenues for...
Strategic and Regulatory Developments in Biotech and Public Health
Key policy and industry trends shaping biotech include drugmakers forming coalitions to lobby against Medicare drug price negotiations, reflecting ongoing tensions over pricing reforms. The...
Bayer-Kumquat KRAS G12D Deal: $1.3B Precision Oncology Bet
Bayer AG has entered a global license and collaboration agreement with Kumquat Biosciences to develop and commercialize Kumquat's KRAS G12D inhibitor, a drug candidate targeting one of the most...
FDA Approves Insmed’s Brinsupri for Non-Cystic Fibrosis Bronchiectasis
The FDA has approved Insmed’s Brinsupri (brensocatib), the first and only treatment for non-cystic fibrosis bronchiectasis (NCFB). This DPP-1 inhibitor offers a new therapeutic option for an...
AI and Deep Learning Push Precision Genome Editing Forward
Researchers have integrated artificial intelligence with CRISPR technology to enhance precision in genome editing. A Nature Biotechnology publication details a deep learning-assisted design of...
Clinical Advances: Immunotherapies and Combo Regimens in Cancer and Leukemia
Recent clinical trial results signal progress in cancer immunotherapy and chemotherapy alternatives. Novartis’ monoclonal antibody ianalumab achieved two Phase 3 wins in autoimmune disorders,...
Innovations in mRNA Delivery and Gene Therapy Targeting Precision and Safety
Monash University researchers have developed a versatile nanobody-antibody system to enhance mRNA lipid nanoparticle (LNP) targeting to specific organs, improving therapeutic precision without...
AI and Digital Tools Transform Biotech and Medical Research Landscape
Artificial intelligence applications continue to make strides across biotech fields. Tahoe Therapeutics raised $30 million to build large-scale AI models of human cells for drug discovery....
Advances in Energy Storage: Lithium and Zinc Battery Technology Breakthroughs
Researchers in energy storage technologies have achieved notable innovations. Lithium metal batteries receive performance boosts through novel electrolyte designs, improving energy density and...
Breakthroughs in Infectious Disease: Targeting Viruses, Parasites and Antimicrobials
Infectious disease research uncovers novel mechanisms and potential therapies. A new protein therapy emerges as the first-ever antidote for carbon monoxide poisoning. Studies reveal dopamine...
Financial and Industry Moves: Fundraising, Layoffs, and Market Trends
Biotech financing and corporate shifts characterize the current market landscape. Hatteras Venture Partners closed over $200 million across two life sciences funds aimed at early-stage...
Bayer and Kumquat Ink $1.3B KRAS G12D Cancer Drug Deal
Bayer has entered a global exclusive license and collaboration with Kumquat Biosciences to develop and commercialize a KRAS G12D inhibitor, a mutation implicated in 25% of human cancers including...
FDA Approves First Drug for Non-Cystic Fibrosis Bronchiectasis
Insmed received FDA approval for Brinsupri (brensocatib), the first approved treatment for non-cystic fibrosis bronchiectasis (NCFB), a chronic lung disease affecting approximately 500,000 U.S....
AI Advances Precise Genome Editing Using Deep Learning and Microhomology Templates
Researchers at the University of Zurich developed “Pythia,” an AI model that predicts DNA repair outcomes post-CRISPR cutting, enabling the design of microhomology-based DNA repair templates that...
Novel Cancer Immunotherapy Targets Triple-Negative Breast Cancer Resistance
University of Pittsburgh scientists identified lncRNA EPIC1 as a driver of immunotherapy resistance in triple-negative breast cancer (TNBC). EPIC1 suppresses type I interferon responses...
Insmed’s Lung Drug Brinsupri Shows Commercial and Clinical Progress
Insmed’s Brinsupri, a DPP1 inhibitor for bronchiectasis, is poised as a blockbuster following FDA approval and positive clinical trials. The company confirmed plans for dual doses to provide...
AI Models Reveal New Approaches to Drug Discovery and Cancer Treatment
Multiple studies highlight the integration of AI in drug discovery and cancer research. KAIST developed an AI model for autonomous design of drug candidates targeting cancer mutations. Meanwhile,...
Breakthroughs in AI-Enabled Diagnostics and Imaging Transform Healthcare
Cutting-edge AI and deep learning tools are revolutionizing medical diagnostics. New models detect cervical precancer with compact microscopes, enhance ultrasound 3D reconstruction, and improve...
New Therapeutics Target KRAS and Autoimmune Diseases with Phase III Advances
Two significant clinical successes emerged this week: Novartis achieved back-to-back Phase III wins for ianalumab in Sjögren’s disease and primary immune thrombocytopenia, demonstrating promising...
Novel Protein-Based Antidote Shows Promise Against Carbon Monoxide Poisoning
University of Maryland School of Medicine researchers engineered a new protein therapy that rapidly and selectively removes carbon monoxide (CO) from the bloodstream during acute poisoning...