Get the Daily Brief
Latest Biotech News
Breakthrough Genetic Regulation Mechanism Discovered in Embryo Development
Researchers at the MRC London Institute of Medical Sciences have identified a unique DNA element that functions as a 'dimmer switch' to finely control the temporal expression of the critical gene...
New Computational Tool Illuminates Water’s Role in Drug Discovery
Scientists at St. Jude Children’s Research Hospital have unveiled ColdBrew, a novel computational algorithm that models protein-bound water molecules under physiological conditions. This method...
Multi-Cancer Early Detection via Metabolomic Profiling Gains Momentum
Startup Wholomics has introduced a metabolomic platform employing nuclear magnetic resonance technology to detect cancer signatures across a broad spectrum of tumor types in serum samples. Unlike...
Pioneering Organoid Model Simulates Chemotherapy Response in Esophageal Cancer
Researchers led by Donald Ingber and Lorenzo Ferri have developed an advanced organ chip platform that integrates patient-derived organoids with elements of the tumor microenvironment to predict...
FDA Policy Shifts Spur Debate over Rare Disease Drug Approvals
Upcoming landmark decisions and reviews of the FDA’s rare disease policies will test the agency’s stance on biomarker-based accelerated approvals for orphan drugs. Regulatory unpredictability...
Unveiling the Role of PTGIR Immune Checkpoint in Cancer Immunotherapy
A collaborative study from Van Andel Institute uncovers PTGIR, a prostacyclin receptor, as a novel immune checkpoint regulating CD8+ T cell exhaustion in cancer. PTGIR engagement by prostacyclin...
Insights into Childhood Overweight Trends in China Signal Rising Health Crisis
A comprehensive longitudinal study published in the International Journal of Obesity documents a persistent increase in childhood overweight and obesity rates across all Chinese provinces from...
Major Biopharma Executive Moves and Industry Investments Highlighted
Recent appointments include Martin Stumpe named as Danaher’s Chief Technology and AI Officer, and Marjorie Green joining NeoGenomics’ board with a strong oncology development background. Qiagen’s...
FDA Eases Access Restrictions on CAR-T Therapies
The U.S. Food and Drug Administration has removed the Risk Evaluation and Mitigation Strategies (REMS) requirements for all approved CAR-T cell therapies, including those from Bristol Myers...
Alphabet’s Calico Licenses Mabwell’s IL-11 Therapeutics for Aging
Calico Life Sciences, an Alphabet-backed longevity-focused biotech, has secured exclusive global rights (excluding greater China) to Mabwell Bioscience’s clinical-stage monoclonal antibody,...
Breakthroughs in Molecular and Cellular Mechanisms in Disease and Development
Prominent studies have unveiled critical basic science advances that will impact biotech and therapeutic research. Notably, investigations into ribosome biogenesis reveal its m6A-mediated...
Innovative Diagnostic and Therapeutic Tools in Oncology and Rare Diseases
Recent developments showcase advancements in diagnostic platforms and candidate therapies for cancer and rare diseases. Wholomics introduced a metabolomic cancer detection assay sensitive across...
AI and Computational Platforms Accelerate Drug Discovery and Target Identification
Cutting-edge AI-driven models and computational tools are enhancing drug target identification and nanoparticle characterization. OutSee’s Nomaly platform applies structural and functional genomic...
Regulatory Dynamics and Industry Leadership in Biotech
The evolving regulatory landscape and executive movements shape biotech’s strategic prospects. BioCentury reports FDA commissioner Marty Makary's controversial intervention attempt in KalVista’s...
Clinical and Translational Research Advancements
Several clinical research breakthroughs highlight progress against difficult diseases. St. Jude researchers characterized how B-cell developmental stages influence pediatric leukemia treatment...
Breakthroughs in Biomanufacturing and Clinical Facility Expansion
German contract development and manufacturing organization Vetter launched construction of a $285 million clinical manufacturing site in Des Plaines, Illinois, expanding aseptic drug production...
Genetic and Molecular Insights into Cancer and Aging
Recent studies uncover molecular mechanisms influencing cancer and aging. University of Michigan’s Rogel Cancer Center revealed how distinct classes of FOXA1 mutations drive prostate cancer...
Environmental and Ecological Biotech Innovations
Environmental research integrates biotechnology to address ecological challenges. Studies reveal groundwater’s pivotal role in sustaining coral reef chemistry and biology, highlighting...
Calico’s $596M Deal for Mabwell's Anti-Aging Therapeutics
Alphabet's Calico Life Sciences has secured exclusive global rights, barring greater China, to Mabwell Bioscience's IL-11 targeted monoclonal antibody 9MW3811, an investigational asset intended...
FDA Eases Access to CAR-T Cell Therapies
The FDA has removed the Risk Evaluation and Mitigation Strategies (REMS) for approved CAR-T therapies targeting BCMA and CD19 antigens, streamlining safety monitoring protocols established since...