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FDA Grants Full Approval to Precigen's Gene Therapy for Rare Respiratory Disease
The FDA has granted full and expedited approval to Precigen Inc.'s gene therapy, Papzimeos (zopapogene imadenovec), targeting adults with recurrent respiratory papillomatosis (RRP), a rare chronic...
Pfizer’s Sickle Cell Drug Candidate Fails Phase III Trial
Pfizer announced the failure of its sickle cell drug candidate, inclacumab, in a pivotal Phase III clinical trial, where it did not demonstrate significant reduction in vaso-occlusive crises...
New CD40 Agonist Antibody Shows Promise in Metastatic Cancer Trial
Rockefeller University researchers have reported encouraging clinical outcomes from a Phase I trial of 2141.V11, an Fc-optimized CD40 agonistic antibody administered intratumorally to metastatic...
Breakthrough Imaging Captures Human Embryo Implantation in Real Time
Researchers at the Institute for Bioengineering of Catalonia and Dexeus University Hospital have captured, for the first time, high-resolution three-dimensional videos of human embryo...
AI Technologies Accelerate Drug Discovery and RNA Therapeutics Development
Multiple innovations have leveraged artificial intelligence to accelerate drug discovery pipelines and RNA vaccine design. Researchers at MIT utilized generative AI to design novel antibiotic...
Eli Lilly Raises European Drug Prices to Align with US Market
Eli Lilly announced a planned increase in the list prices of its weight-loss drug Mounjaro across Europe, including a 170% hike in the United Kingdom, aligning pricing closer to US levels. This...
Advances in Neonatal Respiratory Care and Drug Trials for Preterm Infants
Clinical research is advancing treatments for bronchopulmonary dysplasia (BPD) in preterm infants. Airway Therapeutics announced expansion of a multinational Phase III trial testing zelpultide...
Breakthroughs in Cancer Metabolism and Immunotherapy Biomarkers
Recent studies have uncovered novel metabolic vulnerabilities and biomarkers pivotal for improving cancer therapy. Research highlights include: the discovery of immune cell exhaustion reversal...
Innovations in Biomanufacturing and Cell Therapy Manufacturing Expansion
Made Scientific celebrated the grand opening of a new 60,000-square-foot GMP facility in Princeton, NJ, designed to support commercial-scale cell therapy manufacturing. The facility integrates...
Regulatory and Industry Landscape: Vaccine Policy and Biopharma Financing Trends
The US Department of Health and Human Services has reinstated the vaccine safety task force nearly three decades after its dissolution, aiming to improve oversight and vaccine safety amidst public...
FDA Accelerates Gene Therapy Approval for Rare Respiratory Disease
The U.S. Food and Drug Administration has granted full and rapid approval to Precigen Inc.’s gene therapy, Papzimeos (zopapogene imadenovec), addressing recurrent respiratory papillomatosis (RRP),...
AI-Powered Antibiotic Discovery Targets Resistant Bacteria
Researchers at MIT have developed a cutting-edge generative artificial intelligence platform to design novel antibiotic molecules effective against highly resistant pathogens including Neisseria...
Innovative Immunotherapy Shows Systemic Impact in Metastatic Cancer
A Phase I clinical trial of an Fc-engineered CD40 agonist antibody (2141.V11), administered intratumorally, demonstrated remarkable systemic antitumor efficacy in metastatic cancer patients. Among...
Breakthrough Imaging Captures First Real-Time Human Embryo Implantation
Scientists at the Institute for Bioengineering of Catalonia and Dexeus University Hospital have captured the first real-time, three-dimensional recordings of human embryo implantation. Using a...
Biopharma Raises Funding Amid Record Deal Activity and IPO Drought
Biopharma dealmaking excluding mergers and acquisitions surged to $164 billion in the first seven months of 2025, marking a 36% increase over 2024, driven by several blockbuster collaborations and...
Eli Lilly Raises Drug Prices in Europe to Offset US Costs
Pharmaceutical company Eli Lilly announced plans to substantially increase prices for its weight-loss drug Mounjaro and other drugs in European markets, including a 170% hike for Mounjaro's...
Advances in AI and Machine Learning Transform Drug Development
Recent studies highlight the transformative impact of artificial intelligence (AI) across drug discovery and biological data generation. MIT researchers demonstrated AI-driven design of novel...
Neuroscience Innovations Enable Direct Mind-to-Text Communication
A novel brain-computer interface developed by neuroscientists allows individuals with severe speech impairments to communicate by decoding inner speech directly from motor cortex neural signals....
Breakthrough Nanobody Therapy Targets Lung Cancer Precisely
Researchers at the Korea Research Institute of Bioscience and Biotechnology have developed a pioneering nanobody-based therapy designed for precise targeting of lung cancer tumors. This innovative...
FDA Reinstates Vaccine Safety Task Force Amid Controversy
The U.S. Department of Health and Human Services has revived the disbanded Task Force on Safer Childhood Vaccines following pressure from a lawsuit endorsed by anti-vaccine advocacy groups....