Latest Biotech News

Bristol Myers Squibb said it will merge parts of its R&D operation under Cristian Massacesi, the company’s chief medical officer and head of development work, while Robert Plenge is stepping away...

Blackstone Life Sciences committed up to $1.5 billion to support development of Pfizer’s ex-Metsera GLP-1 obesity candidate berobenatide. The co-funding arrangement is structured to provide...

Cystadane (n-bic-d) trial data in an open-label phase Ib/II study showed reduced biomarkers and functional gains in children with aspartylglucosaminuria. Investigators reported significant...

A Nature Reviews Molecular Cell Biology review reframed PARP1’s role in DNA damage response as a geometry- and context-interpreting regulator rather than a uniform sensor. The authors connect PARP...

A preclinical study reported that novel PARP inhibitor No. 123 suppressed cervical tumor progression in mice by combining direct cytotoxicity with immune activation through the cGAS-STING pathway....

Researchers engineered silk fibroin microspheres designed to sequentially release dexamethasone and epidermal growth factor to modulate inflammation and promote repair. In preclinical models, the...

A retrospective cohort study found that adding 18F-sodium fluoride PET/CT to staging in newly diagnosed nasopharyngeal carcinoma reclassified tumor or metastasis categories in a minority of...

A deep learning framework for skin lesion classification quantified diagnostic uncertainty and calibrated predicted probabilities on the HAM10000 benchmark. The approach combined DINOv2...

A prospective multicenter cohort study across 31 hospitals in China reported that a novel antimicrobial regimen improved treatment success and reduced failure in patients with retreated...

Researchers identified lymphatic retinol binding protein 1 (RBP1) as a driver of metastatic dissemination in triple-negative breast cancer. The study reported that tumor-associated lymphatic...

Merck KGaA secured an FDA approval for pimjetmi for tenosynovial giant cell tumor, marking another milestone in the company’s rare-tumor strategy and adding to its expanding portfolio in less...

A phase 2 study reported early evidence that a triplet regimen combining regorafenib, chemotherapy, and nivolumab was safe and remodeled the tumor microenvironment in advanced gastric cancer,...

Researchers reported that peripheral immune dynamics can track response in early-stage triple-negative breast cancer treated with pembrolizumab-containing neoadjuvant chemotherapy. Increases in...

A lab study described an “inhaled living medicine” approach: engineered bacteria designed to disrupt ventilator-tube biofilms reduced Pseudomonas aeruginosa biofilm thickness in pigs without...

Researchers introduced evidence for a genetic protective mechanism relevant to neurodegenerative proteinopathies: the Christchurch APOE mutation prevented tau and alpha-synuclein accumulation in...

A retrospective report highlighted a rapid platelet recovery in a patient with refractory immune-mediated thrombotic thrombocytopenic purpura after adding caplacizumab. The case adds practical...

A three-year retrospective cohort study of 3,819 participants found that prediabetes subtypes follow distinct trajectories and carry differing risks for early kidney filtration impairment. The...

Researchers reported that supine positioning in clinical monitoring is associated with substantially higher respiratory event rates and nocturnal oxygen desaturation than non-supine positioning in...

A narrative review cautioned that isolated PET findings for pancreatic masses should not automatically trigger curative surgery. The authors emphasized PET/CT interpretation should reflect...

Neurosterix announced a $105 million Series B to advance its schizophrenia candidate and expand development tied to Bristol Myers Squibb’s target space, according to the provided company brief....