Get the Daily Brief
Latest Biotech News
Advances in AI and Molecular Technologies Enhance Drug Discovery
Cutting-edge AI-driven tools and molecular platforms are transforming drug development and diagnostics. Cadence Molecular Sciences launched ROCS X, an AI-powered molecular screening software...
Breakthroughs in Cancer Therapeutics and Diagnostics
Novel therapeutic candidates and diagnostics advance cancer care. Star Therapeutics secured $125 million to push its monoclonal antibody VGA039 targeting bleeding disorders with potential in von...
Polymyxin B’s Energy-Dependent Mechanism Illuminates Antibiotic Action
New research reveals polymyxin B, a last-resort antibiotic against multidrug-resistant Gram-negative bacteria, kills only metabolically active cells by inducing detrimental outer membrane...
COVID-19 Vaccine Boosters Show Durable Immunity in Long-Term Study
A rigorous 24-month longitudinal study in Indonesia compared the immunogenicity of fractional versus standard dose COVID-19 vaccine boosters in healthy adults. Published in Nature Communications,...
Innovations in Radiation Therapy Match Surgery Outcomes in Lung Cancer
A landmark decade-long clinical trial has established that stereotactic radiation therapy delivers survival outcomes on par with surgical resection in early-stage non-small cell lung cancer...
New mRNA Vaccine Shows Promise in Treating Macular Degeneration
Japanese researchers developed an mRNA vaccine that suppresses pathological retinal neovascularization underlying age-related macular degeneration in mouse models. This intramuscular vaccine...
Direct-to-Patient Platforms Respond to Drug Pricing Pressures
With US drug pricing reforms looming, pharmaceutical firms have introduced direct-to-patient models to enhance medication accessibility and affordability. PHIL launched its Direct-to-Patient 2.0...
FDA Leadership Change and Regulatory Policy Shifts in Drug Approval
Dr. Anthony Letai, a renowned oncologist and cell death pathway expert, has been appointed director of the National Cancer Institute, promising a renewed focus on biomarker discovery and...
Exercise and Immune Recovery in Post-COVID Syndrome
A randomized controlled trial presented at the European Respiratory Society Congress demonstrated that structured exercise significantly recalibrates immune function in individuals with post-COVID...
Genmab's $8B Merus Acquisition Transforms Head and Neck Cancer Pipeline
Genmab has finalized an $8 billion all-cash acquisition of Dutch biotech Merus, securing rights to its phase III-stage bispecific antibody, petosemtamab, targeting head and neck cancer....
FDA Takes Closer Look at Surrogate Endpoints Under CDER Director Tidmarsh
George Tidmarsh, director of the FDA's Center for Drug Evaluation and Research (CDER), signaled a review of the agency's use of surrogate endpoints for drug approval. These endpoints, which rely...
Revolutionary AI-Based Stool Test Achieves 90% Accuracy for Early Colorectal Cancer Detection
Researchers at the University of Geneva developed an AI-powered stool test that offers non-invasive, early detection of colorectal cancer with approximately 90% accuracy. This screening tool could...
Breakthrough Study Reveals How Polymyxin B Destroys Bacterial Defenses
New research from University College London and Imperial College London elucidates how Polymyxin B, a last-resort antibiotic, kills Gram-negative bacteria by triggering active disruption and...
First-in-Human Trial of IL-12 Drug tolododekin Alfa Shows Promise in Solid Tumors
Clinical trial results for tolododekin alfa, an interleukin-12 (IL-12) anchored drug conjugate, reveal successful harnessing of IL-12’s immunomodulatory effects with reduced systemic toxicity. The...
Liposomal Iron Shows Major Improvement in Pediatric CKD Anemia Management
A randomized clinical trial highlights the efficacy of liposomal iron therapy in treating iron deficiency anemia among pediatric chronic kidney disease (CKD) patients. The treatment significantly...
Groundbreaking AI Model Differentiates Glioblastoma from Similar Brain Tumors in Real Time
A team from Harvard Medical School unveiled an AI tool capable of accurately distinguishing glioblastoma from other visually similar brain tumors intraoperatively. This real-time diagnostic...
Revolutionary mRNA Vaccine Halts Retinal Neovascularization in Age-Related Macular Degeneration Models
Researchers at the Institute of Science Tokyo developed an mRNA vaccine that suppresses pathological blood vessel growth in mouse models of age-related macular degeneration (AMD). Delivered...
Novel Analytical Tool COOKIE-Pro Advances Covalent Inhibitor Drug Optimization
Baylor College of Medicine scientists introduced COOKIE-Pro, a cutting-edge analytical platform that delivers unprecedented insight into covalent inhibitor interactions with the proteome. By...
Genmab Names In-House CEOs as GSK and Merck KGaA Also Appoint Internal Leaders
Genmab, GSK, and Merck KGaA have all appointed new chief executives sourced internally, reflecting a trend toward continuity and leveraging internal expertise within leading biopharma firms. This...
Genmab's $8B Purchase of Merus Secures Head and Neck Cancer Candidate
Danish biopharma Genmab has agreed to acquire Dutch company Merus for $8 billion in cash, gaining full rights to Merus's late-stage bispecific antibody petosemtamab, targeted for head and neck...