A federal judge in Maine issued an order blocking implementation of the government's current iteration of the 340B rebate pilot program pending further order. The decision represents a legal setback for the administration’s plan to modify drug pricing and rebate mechanics under the 340B program and is being viewed as a win for drugmakers who had challenged the pilot in court. The temporary injunction pauses planned changes slated to take effect Jan. 1 and creates regulatory uncertainty for hospitals, manufacturers and payers preparing operational adjustments. Stakeholders now await further judicial action or negotiated settlements that could reshape the scope and timeline of any 340B reforms. The ruling also signals continued litigation risk around federal efforts to alter drug pricing mechanisms and sets the stage for further industry lobbying and legal maneuvering.