Latest Biotech News

Caribou Biosciences moved to wind down its allogeneic CAR-T programs and cut workforce after failing to secure financing to complete late-stage plans. The company said it will discontinue...

PhRMA escalated legal challenges to the Trump administration’s drug-pricing demo program, pushing back on Medicare “most-favored nation” concepts. In separate filings, the trade group argues the...

The European Medicines Agency signaled major changes to the Clinical Trials Information System to meet proposed Biotech Act requirements. In a plan outlined by the agency, CTIS would need...

Roche announced its fourth China deal since August, teaming up with Chinese biotech Defand on targeted protein-degrader development. The reported deal value is just under $1 billion if milestones...

DaltonTx said it expanded its AI engine for antibody discovery and management, including adding upstream process support such as assays and experimental outcomes. The company positions the system...

New evidence underscores both clinical promise and economic friction for GLP-1 therapies. A meta-analysis of randomized trials found higher-dose oral orforglipron (36 mg maintenance) produced...

Shionogi agreed to acquire IntraBio for $2 billion to expand its rare disease portfolio around Niemann-Pick disease type C. The deal includes the acquisition of Aqneursa (levacetylleucine), which...

AI-based imaging tools are increasingly being validated for preoperative risk stratification and surgical decision-making. One study in breast cancer reported a machine learning model that...

Cerevance reported Phase 3 results for solengepras, an investigational add-on pill for Parkinson’s disease designed to reduce daily “off” time without directly targeting dopamine. The company said...

A seven-year hospital study in Northeast India reported the spread of non-fermenting Gram-negative bacteria carrying last-resort resistance genes. Researchers identified metallo-beta-lactamase and...

The European Medicines Agency said the EU Clinical Trials Information System (CTIS) will need a major rebuild to support changes proposed under the EU Biotech Act, affecting roughly 70% of current...

The FDA approved an oral pancreatic cancer therapy, daraxonrasib, after results showed it nearly doubled survival, according to reporting tied to Sylvester Comprehensive Cancer Center research....

Caribou Biosciences said it will discontinue two allogeneic CAR-T programs and pursue strategic alternatives after failing to secure financing for planned late-stage development. The...

Researchers reported a mechanistic oncology-adjacent immune finding: blocking the sugar-linkage enzyme ST6GAL1 reverses a “sugar switch” on macrophages, restoring tumor-fighting behavior and...

A deep learning system called MedSegNet-AXU segmented multiple sclerosis lesions from 3D MRI with a reported 98.58% Dice score and used radiomics plus graph neural networks to predict sensory,...

Ultragenyx sold a priority review voucher for $210 million to an undisclosed buyer, marking one of the richest PRV monetizations reported this year. The company said it still has another voucher...

Teladoc Health announced it is adding contactless vitals and an ambient AI scribe to its Solo smart care virtual-visit platform for hospitals and health systems. The update is designed for use...

A large real-world study found that GLP-1 receptor agonists are associated with sharply lower heart failure, pulmonary hypertension, heart attack, and death risks among obese patients with...

AlecOr-backed work advanced a mechanism-based Parkinson’s strategy: Cerevance reported in a phase 3 trial that solengepras reduced daily “off” time in Parkinson’s patients, positioning the pill as...

A study in glioma preclinicals found that spatially fractionated mini-GRID radiotherapy reduced senescence markers and persistent DNA-damage signals while preserving anti-tumor effects compared...