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Roche Enters MASH Market with $3.5B 89bio Acquisition
Roche announced a $3.5 billion acquisition of biotech firm 89bio, gaining control of pegozafermin, a drug candidate targeting metabolic dysfunction-associated steatohepatitis (MASH), a liver...
AI-Generated Bacteriophage Genomes Demonstrate Functionality
Researchers at Stanford University and Arc Institute unveiled the first successful generation of complete, functional bacteriophage genomes designed by artificial intelligence. Using Evo...
Gene Editing Advances Reduce Prime Editing Errors
Scientists have engineered new Cas9 proteins that substantially diminish unintended genomic alterations in prime editing, bolstering the precision of this promising genome-editing approach. Prime...
Innovative Soft Electrodes Enable Dynamic Brain-Computer Interfaces
Researchers introduced a novel class of soft, high-density biofibers integrating multifaceted sensing and stimulation capabilities for brain-computer interfaces. Unlike traditional static neural...
Novel Cancer Therapeutic Combines Immune Modulation and Chemotherapy
Swiss researchers unveiled a fusion protein that combines tumor immune checkpoint disruption with selective immune activation to combat cancer. This bifunctional molecule simultaneously inhibits...
Cell Therapy Startup ArsenalBio Halves Workforce Amid Strategic Shift
Arsenal Biosciences confirmed cutting 50% of its staff as the clinical-stage cell therapy startup pivots to focus resources. Despite raising $325 million and partnerships with Bristol Myers...
Pioneering Kidney Assembloids Model Disease and Enable Transplant Research
Scientists at the University of Southern California developed advanced kidney assembloids by merging separate organoids encompassing nephrons and collecting ducts into complex structures....
New CRISPR-Based Noninvasive Test for Tuberculosis Shows Promise
Researchers at Tulane University developed ActCRISPR-TB, a novel diagnostic assay detecting Mycobacterium tuberculosis DNA from simple tongue swabs using integrated isothermal amplification and...
AI Advances Transform Gene Editing Design and Drug Discovery
Innovative artificial intelligence tools are revolutionizing biotechnology research and development through enhanced design capabilities. Stanford Medicine introduced CRISPR-GPT, an AI-powered...
Regulatory Turmoil and Vaccine Policy Challenges in the US
Former CDC Director Susan Monarez testified before the Senate Health Committee, revealing political interference in vaccine recommendation processes by Health Secretary Robert F. Kennedy Jr. Her...
Regeneron’s Garetosmab Cuts Bone Lesions in Rare Disease – FDA Submission Planned
Regeneron Pharmaceuticals reported positive phase III results for garetosmab, a fully human monoclonal antibody targeting activin A, showing significant reduction of new bone growth lesions in...
Eli Lilly’s Oral GLP-1 Pill Outperforms Novo’s Rybelsus in Diabetes Trial
Eli Lilly’s investigational oral GLP-1 receptor agonist, orforglipron, demonstrated superiority to Novo Nordisk’s Rybelsus in a head-to-head Phase 3 trial involving diabetes patients. Orforglipron...
AI Models Generate Functional Bacteriophage Genomes To Fight Drug Resistance
Researchers at Stanford and the Arc Institute have pioneered generative AI models capable of designing complete bacteriophage genomes, advancing beyond single-gene engineering to whole viral...
ArsenalBio Slashes Workforce by Half Amid Strategic Pivot
Arsenal Biosciences, a clinical-stage cell therapy startup noted for its substantial fundraising efforts including a $325 million Series C, has announced a reduction of 50% of its workforce. The...
US COVID Vaccine Policy in Flux amid CDC Leadership Controversy
The US Centers for Disease Control and Prevention is experiencing turmoil following the removal of its director Susan Monarez amid conflicts with Health Secretary Robert F. Kennedy Jr. Kennedy’s...
US Biopharma Giant GSK Commits $30 Billion to Expand US Footprint
Pharmaceutical leader GSK has announced a $30 billion investment plan over five years targeting manufacturing and research and development infrastructure across the United States. This infusion...
Michigan State Develops Analog Neural Processor for Speech Recognition
Researchers at Michigan State University introduced an innovative analog speech recognition system using Resistive Neural Processing Units (RNPUs) operating efficiently at room temperature. This...
USC Scientists Engineer Advanced Kidney Organoids for Disease Modeling
A team from the Keck School of Medicine at USC reported the creation of complex kidney assembloids that combine nephron and collecting duct organoids. These lab-grown structures, transplanted into...
New CRISPR Prime Editors Cut Genomic Off-Target Effects Significantly
Researchers have engineered advanced prime editing techniques employing newly identified Cas9 variants that substantially minimize unintended genetic alterations during genome editing. This...
Duke University Deploys AI for Clinician Support and Cost Reduction
Duke University Health System is implementing a hybrid AI strategy combining homegrown and commercial tools to ease administrative workloads for nurses and improve patient care efficiency. While...