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Precision Genome Editing Scales to Megabase Ranges in Eukaryotes
Chinese researchers have pioneered novel genome editing platforms termed Programmable Chromosome Engineering (PCE), achieving unprecedented megabase-scale DNA manipulations in eukaryotic cells. By...
Vertex Pharmaceuticals Faces Setbacks on Pain Drug Development
Vertex Pharmaceuticals announced the failure of a next-generation non-opioid pain candidate, VX-993, in a Phase 2 trial for acute pain following bunionectomy, resulting in termination of pivotal...
Microplastics Found in Human Blood and Environment: New Analytical Advances
Emerging studies highlight the pervasive infiltration of micro- and nanoplastics in human biological systems and the environment, prompting concerns over health implications. Researchers employ...
Repligen Partners with Novasign to Boost Bioprocessing Digitalization
Repligen announced a strategic partnership with Novasign to integrate advanced machine learning and modeling workflows into its filtration systems, enhancing digitalization and process analytical...
Glioblastoma Research Gains Momentum Through New Trials and Investments
After years of limited progress in glioblastoma treatment due to high clinical failure rates and industry retreat, renewed interest and funding are driving advancements in therapeutics and trial...
AI Advances in Protein Engineering Target Intrinsically Disordered Proteins
Researchers led by Nobel laureate David Baker have harnessed deep learning methods to design peptides capable of binding intrinsically disordered proteins (IDPs), which traditionally have been...
Clinical and Molecular Insights in Cancer, Immunotherapy, and Precision Medicine
A suite of recent studies spanning oncology reveal novel biomarkers, immunotherapeutic targets, and precision medicine tools. Highlights include the identification of Ephrin B3 in cutaneous...
Sophia Genetics Expands AI Collaboration with AstraZeneca Amid Revenue Growth
Sophia Genetics reported a 16% year-over-year revenue increase to $18.3 million for Q2 2025, driven by growth outside biopharma sectors. The company expanded its multimodal AI collaboration with...
Twist Bioscience Revises Fiscal Guidance Following Strong Q3 Growth
Twist Bioscience reported record Q3 2025 revenues of $96.1 million, marking an 18% year-over-year increase driven by 27% growth in next-generation sequencing and 7% growth in synthetic biology...
Breakthrough Genome Editing Technologies: Megabase-Scale Precision Achieved
Researchers from the Chinese Academy of Sciences led by Prof. Gao Caixia have developed two innovative genome editing platforms, collectively termed Programmable Chromosome Engineering (PCE)...
FDA Leadership Changes and Impact on Gene Therapy Approvals
The recent departure of Vinay Prasad as director of the FDA's Center for Biologics Evaluation and Research (CBER) marks a significant turning point in regulatory oversight of gene therapies....
Biotech Market Uncertainty Strains San Diego Life Sciences Hub
San Diego's once vibrant biotech ecosystem is facing a prolonged downturn marked by scarce funding, rising lab vacancy rates, and widespread layoffs. Industry professionals, including former...
Advanced AI and Deep Learning Models Enhance Cancer Diagnostics
Cutting-edge artificial intelligence applications are transforming oncological diagnostics by improving the precision and prediction of tumor characteristics. Notably, researchers have developed a...
Novel Therapeutics and Drug Developments in Oncology and Neurology
Recent breakthroughs include a two-in-one molecule targeting KRAS and MYC oncogenes developed at University of North Carolina, promising new avenues for difficult-to-treat cancers. Another advance...
Microplastics and Nanoplastics: Environmental and Human Health Impacts
Environmental scientists continue to unravel the pervasive distribution and biological effects of micro- and nanoplastics. Studies highlight novel methods for detecting plastic particles in human...
Breakthroughs in Machine Learning and AI Applications in Biotech
Machine learning models have been leveraged to accelerate biotech research and diagnostics. Applications include early prediction of stem cell-derived organoid quality, restaurant demand...
Advanced Imaging and Optical Technologies for Biomedical Research
Innovations in microscopy and imaging technologies are pushing the boundaries of biological research and diagnostics. Developments include a chip-based, label-free super-resolution microscopy...
Biopharma Financial Updates and Strategic Movements
Twist Bioscience reported an 18% rise in Q3 2025 revenues, driven by growth in synthetic biology and next-generation sequencing sectors, prompting a modest revision of its fiscal 2025 revenue...
Emerging Vaccine and Immunotherapy Developments
Recent advances in vaccine and immunotherapy research include Sophia Genetics' 16% revenue growth amid an expanded AstraZeneca breast cancer collaboration focused on AI-driven data integration to...
Precision Genome Editing Scales Megabase Alterations
Chinese researchers led by Professor Gao Caixia have achieved a breakthrough in genome editing by developing Programmable Chromosome Engineering (PCE) systems that enable megabase-scale precise...