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Latest Biotech News

UK Biobank releases 500K metabolomes: 249‑metabolite atlas

November 21, 2025

UK Biobank released the final tranche of metabolomics data covering 249 blood metabolites for roughly 500,000 participants, creating the largest public metabolomics resource to date. The dataset...

Hepta shows cfDNA methylation mirrors liver biology: cfDNA assay proof

November 21, 2025

Hepta, founded by former Grail veterans, published proof‑of‑concept data showing cell‑free DNA (cfDNA) methylation signatures reflect liver tissue biology, including fibrosis and pathway activity....

CDC updates vaccine guidance: agency reopens autism link question

November 21, 2025

Multiple outlets reported that the U.S. Centers for Disease Control and Prevention revised language on a vaccine‑safety webpage to state that claims vaccines do not cause autism are not...

Moderna secures $1.5B financing to pivot toward oncology

November 21, 2025

Moderna disclosed a $1.5 billion financing package as part of a strategic plan to scale seasonal vaccine manufacturing and redeploy revenue into oncology and rare disease programs, aiming to reach...

Abbott to acquire Exact Sciences: $23B bet on cancer diagnostics

November 21, 2025

Abbott announced a definitive agreement to buy Exact Sciences for roughly $21–23 billion, moving the medical-device giant into multi-cancer screening and precision oncology diagnostics. The deal...

GSK picks Flagship partners — Profound and Quotient to mine new targets

November 21, 2025

GSK has selected two Flagship Pioneering portfolio companies — Profound (proteomics) and Quotient (somatic genomics) — as the first collaborators under a multi‑program discovery framework intended...

Contineum’s J&J‑partnered MS drug misses vision endpoints — program under review

November 21, 2025

Contineum Therapeutics reported topline results from its Phase 2 VISTA study of PIPE‑307 in relapsing‑remitting multiple sclerosis (RRMS); the trial missed its primary visual acuity efficacy...

Prime editing breakthrough: single‑agent strategies aim to treat many diseases

November 21, 2025

Researchers led by David Liu at the Broad Institute unveiled PERT — prime editing‑installed suppressor tRNAs — a strategy to convert an endogenous tRNA into a suppressor that can restore protein...

Tessera launches first human test of in vivo gene‑writing platform

November 21, 2025

Tessera Therapeutics confirmed it will start the first‑in‑human trial of its in vivo gene‑writing platform next month, filing clinical steps to test the technology in adults with a rare genetic...

Profluent nets $106M — Bezos‑backed bet to scale AI protein design

November 21, 2025

Profluent closed a $106 million financing round led by Altimeter Capital and Bezos Expeditions to expand large‑scale AI models for protein design across therapeutics, agriculture and...

Function Health hits $2.5B valuation with $298M Series B

November 21, 2025

Function Health raised a $298 million Series B led by Redpoint Ventures, valuing the lab‑testing subscription startup at approximately $2.5 billion. The company offers consumers direct access to...

Bayer’s HER2 lung drug clears FDA — companion NGS test wins clearance

November 21, 2025

Bayer won accelerated FDA approval for Hyrnuo (sevabertinib) in adults with advanced HER2‑mutant non‑small‑cell lung cancer after prior systemic therapy. The decision positions Hyrnuo to compete...

Nurix trims staff as pivotal BTK degrader DAYBreak trial kicks off

November 21, 2025

Nurix Therapeutics announced a targeted workforce reduction while initiating a pivotal Phase 2 (DAYBreak) trial of bexobrutideg, an oral BTK degrader aimed at relapsed or refractory chronic...

CDC changes vaccine web language — experts and health groups push back

November 21, 2025

Multiple health organizations and scientific outlets flagged a revision to the CDC’s vaccine safety web content that introduced language suggesting uncertainty about whether vaccines can cause...

Abbott to buy Exact Sciences: $21B cash, enters cancer-diagnostics

November 21, 2025

Abbott announced a definitive agreement to acquire Exact Sciences, the maker of Cologuard and Oncotype DX, in a transaction that values Exact at roughly $21 billion in cash and about $23 billion...

Bayer’s HER2 lung pill clears FDA — companion CDx validated

November 21, 2025

The FDA granted approval to Bayer’s oral HER2‑directed drug Hyrnuo for adults with locally advanced or metastatic HER2‑mutant non‑small cell lung cancer, clearing a new targeted option for...

Contineum’s J&J‑partnered MS drug misses endpoints; company re‑examines data

November 21, 2025

Contineum Therapeutics reported that PIPE‑307, an oral M1 receptor antagonist developed with Janssen, failed to meet its primary efficacy endpoint in a Phase 2 VISTA trial in relapsing‑remitting...

Nurix trims staff as pivotal BTK degrader DAYBreak trial kicks off

November 21, 2025

Nurix Therapeutics announced a targeted workforce reduction while initiating the DAYBreak pivotal Phase 2 trial of its oral BTK degrader bexobrutideg in relapsed or refractory chronic lymphocytic...

Ensoma halves workforce after shifting from platform to clinic

November 21, 2025

Ensoma disclosed a roughly 50% reduction in headcount as it transitions from platform development toward clinical execution, focusing resources on its lead clinical candidate EN‑374 for X‑linked...

Cassidy Bio raises $8M to build AI platform for gene‑editing design

November 21, 2025

Tel Aviv‑based Cassidy Bio closed an $8 million seed round to develop an AI platform that predicts optimal combinations of guide RNAs, editing enzymes and delivery modalities for therapeutic...