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Funding for LGBTQ+ behavioral health platform
Allswell raised a $7 million seed round to expand its LGBTQ+-focused behavioral health platform, led by Rethink Impact with participation from Magnify Ventures, Ulu Ventures and Hopelab Ventures....
In vivo CAR-T as next-gen universal immune therapy concept
A review in Immunity & Inflammation lays out the evolving case for in vivo CAR-T—shifting from multi-week, ex vivo manufacturing toward engineering T cells inside the patient. The article, led by...
CAR-T off-the-shelf outcomes tied to immune rejection and CAR T fitness
MD Anderson researchers reported that success with off-the-shelf CAR T therapies depends on two measurable factors: pre-existing immune rejection and the intrinsic fitness of donor-derived CAR T...
Manufacturing and access gap for antibiotic delivery
A commentary published by MedCity News argues that the world’s antibiotic scarcity is not primarily a scientific discovery problem—rather, it is an access and market-entry failure that prevents...
Clinical imaging biomarkers for high-risk disease
Multiple studies highlighted new imaging-based approaches to identify patients at risk earlier or more precisely across oncology. One analysis in the EQUIP study reported that a next-generation...
Oncology pipeline signal: CDK7 inhibition in resistant HR+/HER2− breast cancer
A randomized trial in Nature Communications reported that the oral CDK7 inhibitor samuraciclib plus fulvestrant improved clinical benefit rates in women with advanced HR-positive, HER2-negative...
Gene-targeted HIV therapy penetrates lymph node reservoirs
A randomized trial using in situ viral imaging and mass spectrometry reported that first-line dolutegravir/lamivudine therapy reaches HIV-1 infected cells within lymph node tissue and coincides...
Immune checkpoint therapy monitoring for liver transplant recurrence risk
Researchers in Beijing reported that soluble PD-1 (sPD-1) measured the day before liver transplantation can flag recurrence risk in patients who received immune checkpoint inhibitors before...
VeloSource expansion with UPMC Enterprises investment
UPMC Enterprises invested in VeloSource to expand the AI-enabled clinician staffing platform. The move targets workforce operations, with UPMC planning further development of the technology for...
Antibiotic stewardship: vaccination linked to reduced antibiotic use
A global scoping review reported that vaccination programs measurably reduce antibiotic consumption and drug-resistant infections, positioning immunization as a lever for antimicrobial...
AI drug discovery and targeted cancer therapeutics
A study from Insilico Medicine said it will present first-in-human data for ISM6331, an AI-designed pan-TEAD inhibitor, at ESMO 2026. The TEAD pathway is implicated in multiple cancers through...
HIV treatment optimization via drug penetration and regimen strategies
A randomized trial combining in situ viral imaging and mass spectrometry reported that standard first-line dolutegravir/lamivudine penetrates lymph node reservoirs, coinciding with a rapid decline...
Cell therapy engineering and immune control in CAR T
MD Anderson reported new data on why off-the-shelf CAR T therapies succeed for some patients but fail for others. The study found that pre-existing immune rejection and intrinsic donor CAR T cell...
Immunotherapy and immune-checkpoint biomarker refinement
A study reported in the immunotherapy space suggested not all immune checkpoint inhibitor side effects are equal for survival. The work challenges the common clinical interpretation that adverse...
Myopia therapeutics: atropine eye drops show stronger slowing effect
A two-year randomized controlled trial in Shanghai found that stronger atropine eye drops meaningfully slowed severe myopia progression in children with high myopia. The study evaluated nightly...
Cancer diagnostics and rapid tissue-to-decision tools
Patient-derived microtumors grown from tiny needle biopsy samples were reported to predict which breast cancer drugs would work, with results aligning with actual clinical outcomes in a short 2–3...
Neutrophil/immune evasion mechanisms in cancer
A study described neutrophils’ role in liver cancer immune evasion by identifying NET-linked gene scores that point to candidate mechanisms. The work frames cancer escape as not just T-cell...
Sepsis and organ-injury prediction using AI models
An interpretable machine learning model was reported to predict 7-, 14-, and 28-day mortality in sepsis-associated liver injury, outperforming modified SOFA and MELD-Na in an independent Chinese...
Lung and radiation oncology safety: radiotherapy triggers herpes reactivation
A retrospective study reported that radiotherapy for cervical cancer may trigger herpes virus reactivation, with reactivation observed in a subset of women and exclusively among cervical cancer...
Diabetic foot and amputation outcomes predicted by routine lab tests
A retrospective study of geriatric diabetic foot patients reported that a simple score based on preoperative hemoglobin, platelet count, and albumin strongly discriminated 24-month mortality after...