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Breakthroughs in Brain-Computer Interfaces Enable Inner Speech Communication
Cutting-edge neural prosthetics have advanced to decode inner speech, enabling individuals with severe speech impairments to communicate by thinking their intended sentences. This system builds...
Regulatory Shifts and Policy in US Biotech and Pharmaceutical Sector
The US biotech and pharmaceutical landscape faces significant regulatory changes and political pressures. An executive order from the Trump administration aims to increase domestic pharmaceutical...
Clinical Advances in Cancer and Immunotherapy
Recent clinical research reveals promising advances as well as challenges in oncology. A Phase 1 trial injecting a modified antibody directly into tumors showed promising responses in metastatic...
Innovations in Energy Storage and Battery Technology
Advances in battery materials and manufacturing continue to accelerate, addressing safety, efficiency, and environmental sustainability. New developments include a quasi-solid electrolyte...
Genomic and Molecular Insights in Disease and Development
Cutting-edge genomic research continues to illuminate mechanisms underlying human health and disease. Work on human-accelerated regions (HARs) demonstrates their influence on neural development...
Bayer-Kumquat Deal Targets KRAS G12D Oncology Mutation
Bayer AG has entered a $1.3 billion global collaboration with Kumquat Biosciences to develop and commercialize a KRAS G12D inhibitor, focusing on pancreatic, colorectal, and lung cancers. The KRAS...
Insmed Wins FDA Nod for Brinsupri in Lung Disease
Insmed received FDA approval for Brinsupri (brensocatib), the first therapy approved for non-cystic fibrosis bronchiectasis (NCFB), a progressive lung disease impacting approximately 500,000 U.S....
AI-Driven Peptide Design Targets Undruggable Proteins
Researchers from the University of Pennsylvania and collaborators introduced PepMLM, an AI model leveraging masked language modeling to design peptide binders using only protein sequence data,...
Sarepta Discloses Safety Data, Sells Arrowhead Stock to Extend Runway
Sarepta Therapeutics released detailed safety outcomes for its Duchenne muscular dystrophy gene therapy Elevidys, affirming a positive benefit-risk profile in ambulatory patients with zero acute...
Schrödinger Halts CDC7 Inhibitor Program After Patient Deaths
Schrödinger discontinued development of its CDC7 inhibitor SGR-2921 following the deaths of two acute myeloid leukemia patients in a phase 1 trial, with one death linked to the therapy due to...
10x Genomics Acquires Scale Bio to Expand Single-Cell Sequencing Capacity
10x Genomics acquired Scale Bio for $30 million in cash plus milestones, integrating combinatorial indexing technology with its Chromium platform to enable ultra-high-throughput single-cell...
Groundbreaking AI Combines Genome Editing with Predictive Repair Templates
A University of Zurich-led team developed 'Pythia', an AI tool for designing microhomology-based DNA repair templates that achieve highly precise and predictable CRISPR/Cas9 genome integrations....
BioElectronics-Assisted Implant Enables Oxygenated Insulin Cell Delivery
Cornell University researchers engineered the BEAM system, a continuously oxygenated macroencapsulation device that supports high-density packing and delivery of insulin-secreting cells without...
Clinical Advances Highlight Dual Therapy in Bladder Cancer Survival
Pfizer and Merck reported compelling survival benefits from combining Pfizer's antibody-drug conjugate Padcev with Merck’s Keytruda in patients with muscle-invasive bladder cancer deemed...
Molecular Evolution System Accelerates Protein Engineering
A team led by Scripps Research’s Peter Schultz developed T7-ORACLE, a synthetic biology platform leveraging an engineered T7 bacteriophage replisome to drive rapid, continuous, and precise protein...
Bayer and Kumquat Strike $1.3 Billion Deal on KRAS G12D Cancer Inhibitor
Bayer AG and Kumquat Biosciences have entered an exclusive global licensing and collaboration agreement to develop and commercialize Kumquat's KRAS G12D inhibitor, a first-in-class drug candidate...
FDA Approves Insmed’s Brensocatib as First Drug for Non-Cystic Fibrosis Bronchiectasis
The U.S. Food and Drug Administration (FDA) has approved Insmed's Brensocatib, branded as Brinsupri, for the treatment of non-cystic fibrosis bronchiectasis (NCFB) in adults and children 12 years...
AI-Driven Advances Transform Cancer Biomarker Discovery and Drug Design
Recent breakthroughs leverage artificial intelligence to accelerate and refine cancer research. Teams at the University of Zurich developed 'Pythia,' an AI tool that predicts DNA repair outcomes...
Novartis Secures Dual Phase III Wins with Anti-BAFF-R Antibody in Autoimmune Diseases
Novartis announced significant clinical successes for its monoclonal antibody ianalumab, which demonstrated efficacy in Phase III trials for Sjögren’s disease and primary immune thrombocytopenia...
mRNA Vaccine Research Faces Federal Funding Retrenchment Amid Public Trust Concerns
Following a recent directive by Health and Human Services (HHS) Secretary Robert F. Kennedy Jr., the Biomedical Advanced Research and Development Authority terminated multiple grants supporting...