Latest Biotech News

Mount Sinai researchers reported that BCMA-directed CAR-T cells can persist in the gut and trigger severe intestinal inflammation in a subset of patients, linking a key toxicity mechanism to where...

Diasome said its HDV-Insulin program for type 1 diabetes is moving into final Phase 3 planning after what it called promising data, targeting hepatocyte delivery through its hepatocyte-directed...

Liquidia’s stock rebounded after the company reached a settlement with United Therapeutics that ended six lawsuits tied to Yutrepia (treprostinil) patent and antitrust claims. As part of the deal,...

A UC San Diego team reported that an EHR algorithm built for California’s new latent TB screening law drove a surge in testing but left the care cascade incomplete. Implementation prompted 547...

Researchers in China developed an explainable deep learning model that analyzes contrast-enhanced CT scans to predict whether non-muscle-invasive bladder cancer will recur within two years after...

A randomized trial using in situ viral imaging and mass spectrometry reported that dolutegravir/lamivudine penetrated lymph node tissue and coincided with a rapid decline in HIV-1–infected cells....

A longitudinal study tracking memory function in lymphoma patients found that older adults recovered memory after CAR T-cell therapy while younger patients showed unexpected cognitive...

UMBC researchers reported that ovarian cancer cells depend on the USP15 enzyme, with USP15 reduction slowing tumor growth, disrupting cell division, limiting spread, and increasing sensitivity to...

A Nature Cancer study reported that stroke remodels the brain’s tumor microenvironment in ways that promote glioma growth, including induction of tumor-associated astrocytes and macrophages. The...

A retrospective study from a pediatric sepsis cohort found that Phoenix Sepsis Criteria outperformed procalcitonin in predicting child sepsis deaths. The result targets risk stratification where...

A prospective phase II pilot study in non-endemic Sichuan reported strong early efficacy for tislelizumab added to induction chemotherapy in high-risk nasopharyngeal carcinoma, with 95.2% response...

New mechanistic findings are pointing to actionable vulnerabilities across solid tumors. A study linked the chromatin partner role of p300 and CBP to YAP-driven transcription in GNAQ-mutant uveal...

A field review is reframing CAR-T manufacturing around an in vivo concept—moving the engineering steps into the patient rather than relying on centralized ex vivo production. The review details...

Two HIV-focused studies reported progress on both cure-directed biology and real-world prevention pipeline performance. In iScience, an iScience study showed that combining a selective CDK9...

Several reports sharpen the stewardship and diagnostics agenda. A market-access critique argued that antibiotic development is not the limiting factor—delivery and access are. In parallel, a...

Cardiac care improvements are being quantified through large data analyses and practical interventions. A Medicare study reported that patients who begin cardiac rehabilitation within 180 days of...

AI is moving from model benchmarks to embedded workflows that affect care delivery. A study found physicians trusted AI consultation advice as much as human specialist input, and adopted...

Startup financing continues to support rare disease targets. OMass secured $310M to advance a therapy for a rare endocrine disorder, aiming to become an alternative to Neurocrine Biosciences’ only...

Metabolic biology and care delivery are converging in diabetes-related findings. A review highlighted mitochondrial dysfunction as a central hub driving diabetic nerve damage, positioning...

Care pathways are being reshaped by both regulation and supportive-care evidence. California’s new latent TB screening mandate triggered a measurable testing increase through an EHR algorithm, but...