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Bayer and Kumquat Partner on $1.3 Billion KRAS G12D Inhibitor Development
Bayer AG entered an exclusive global collaboration with San Diego-based Kumquat Biosciences to develop and commercialize Kumquat’s KRAS G12D inhibitor, a first-in-class agent targeting a key...
Breakthrough Brain-Computer Interface Enables Communication via Inner Speech
Neuroscientists developed a brain-machine interface capable of decoding inner speech by interpreting neural signals from the motor cortex involved in imagined speech. Tested in patients with...
AI Models Design Peptides to Target ‘Undruggable’ Disease Proteins
Researchers at the University of Pennsylvania introduced PepMLM, an AI-driven protein language model designed to develop peptide binders for challenging therapeutic targets lacking resolved...
Spatial Proteomics Firm Syncell Expands with Thermo Fisher Partnership
Taiwanese spatial proteomics company Syncell inked a comarketing agreement with Thermo Fisher Scientific to integrate Syncell’s Microscoop platform for spatial protein purification with Thermo...
New AI-Powered Radiomics Model Predicts Breast Cancer Metastasis
A multicenter study developed a radiomics model based on contrast-enhanced ultrasound imaging that accurately predicts axillary lymph node metastasis and prognosis in breast cancer patients. This...
Intensive AI and Genomics Integration Elevates Cancer Risk Stratification
A novel histology-based risk prediction tool, HIBRID, combines machine learning and circulating tumor DNA analysis to transform colorectal cancer management. Published in Nature Communications,...
Cancer Antibody Trial Shows Complete Responses in Metastatic Patients
A Phase I clinical trial evaluating an engineered CD40 agonistic antibody (2141.V11) demonstrated promising anti-tumor activity in 12 metastatic cancer patients, including melanoma and breast...
Drug Pricing Strategies Shift Amid U.S. Policy Pressure
Eli Lilly announced plans to increase drug prices in Europe and other developed markets in response to the U.S. government's “most-favored-nation” policy under the Trump administration, aiming to...
Breakthrough in Protein Evolution Speeds Therapeutic Development
Researchers at Scripps Research led by Peter Schultz developed T7-ORACLE, a synthetic biology system that accelerates directed evolution of proteins within living cells by harnessing an...
Major Biotech Funding and Strategic Collaborations Spark Innovation
Several biopharmaceutical companies secured substantial funding rounds and forged key partnerships to enhance development pipelines and manufacturing capabilities. Superluminal Medicines entered a...
AI and Computational Advances Transform Drug Discovery and Diagnostics
Artificial intelligence is increasingly integrated into biotechnology, boosting drug design and biomedical research. Researchers at the University of Pennsylvania developed PepMLM, a protein...
New Insights into Obesity Genetics and Predictive Risk Models
A large international consortium enhanced polygenic risk scores (PRS) for obesity by integrating extensive genomic data from over five million participants across diverse ancestries. The improved...
Advances in Gene Therapy and Cell Engineering for Rare Diseases and Cancer
Novel gene editing and cell therapy approaches are advancing treatment for rare diseases and oncology. Researchers developed a universal cDNA insertion strategy via gene editing for chronic...
Innovations in Energy Storage Materials and Battery Technologies
Researchers continue to push the boundaries of energy storage with cutting-edge materials innovations. Developments include a quasi-solid electrolyte, 3D-SLISE, that enhances lithium-ion battery...
Breakthroughs in Clinical and Diagnostic Technologies
Significant strides in clinical diagnostics and patient monitoring have been reported. Ultrasound AI technologies advance prediction of delivery timing, while a new AI-powered wearable system,...
Environmental and Agricultural Sustainability Innovations
Researchers are pioneering sustainable approaches in agriculture and environmental conservation. Expanded policies incentivize low-carbon biofuel crop practices to aid agricultural...
Bayer-Kumquat Cancer Collaboration Targets KRAS Mutation
Bayer and Kumquat Biosciences have launched a global collaboration worth up to $1.3 billion to develop and commercialize Kumquat’s KRAS G12D inhibitor, a promising treatment targeting a mutation...
Insmed Launches First DPP1 Inhibitor for Lung Disease
Insmed has secured FDA approval for Brinsupri (brensocatib), the first dipeptidyl peptidase 1 inhibitor indicated for treating non-cystic fibrosis bronchiectasis (NCFB), a chronic lung condition...
Sarepta Therapeutics Sells Arrowhead Shares amid Financial Moves
Sarepta Therapeutics is divesting its stake in Arrowhead Pharmaceuticals in two tranches to manage milestone payments and extend its cash runway. The sale will help cover a milestone payment and...
AI Advances in Drug Discovery and Design
Researchers are leveraging AI to push boundaries in drug discovery, including MIT’s use of generative AI to develop compounds targeting drug-resistant bacteria such as MRSA and Neisseria...