Latest Biotech News

Researchers have identified the Nrf2-HMOX1 pathway as a key regulator of cisplatin resistance in non-small cell lung cancer (NSCLC), revealing its role in suppressing ferroptosis and helping tumor...

A novel class of translational read-through-inducing drugs (TRIDs) has been developed to restore protein function disrupted by nonsense mutations in Fanconi anemia patients. These small molecules...

New research challenges the established role of Gasdermin E (GSDME) as a pyroptosis executor by demonstrating its paradoxical contribution to glioblastoma’s resistance to pyroptosis and tumor...

Researchers have introduced an AI-powered diagnostic tool using convolutional neural networks (CNNs) with Mel-spectrogram audio analysis to automatically assess the severity of unilateral vocal...

Novo Nordisk’s novel amylin-targeting obesity drug amycretin showed substantial weight loss in phase 1/2 trials, achieving up to 24.3% body weight reduction at the highest dose. However, similar...

Vertex Pharmaceuticals reported that 10 of 12 type 1 diabetes patients treated with their investigational off-the-shelf stem cell therapy, zimislecel, maintained insulin independence for at least...

The U.S. FDA has undertaken significant leadership realignments within the Center for Biologics Evaluation and Research, including the removal of senior executives to align management with...

A novel method employing genetic barcoding has been developed to track cancer cell adaptation and resistance evolution under drug pressure dynamically. This technique enables the precise...

Emerging evidence reveals the tumor suppressor gene CHEK2 not only functions in DNA repair but also modulates anti-tumor immunity in solid cancers. CHEK2 deficiency disrupts homologous...

The US Food and Drug Administration (FDA) has introduced a new pilot commissioner’s national priority voucher program aimed at accelerating review times for biotech companies. Announced alongside...

Vertex Pharmaceuticals has demonstrated promising clinical data for its off-the-shelf stem cell therapy aimed at type 1 diabetes, with 10 out of 12 patients stopping insulin injections a year...

Prothena, an Irish biotech focused on protein dysregulation diseases, is undertaking a major workforce reduction, laying off 63% of employees following the failure of its phase 3 amyloidosis drug...

A novel analysis published in Oncotarget highlights the immunomodulatory role of CHEK2 gene deficiency in solid tumors, extending beyond its classical DNA repair functions. Loss of CHEK2 impairs...

Researchers at Xi’an Jiaotong-Liverpool University and Nanjing University have developed a novel nanoparticle drug delivery system combining PLGA polymer with albumin protein, yielding...

An advanced semi-supervised fusion architecture leveraging speech embeddings has been developed to detect Parkinson's disease with high sensitivity. This AI system analyzes nuanced vocal features...

A University of North Carolina study using AlphaFold 3 protein structure predictions combined with AI and physics-based modeling reveals that the H5N1 avian influenza virus has evolved mutations...

Data from Novo Nordisk's Phase 1/2 trial of the obesity treatment amycretin reveal substantial weight loss gains but atypical dose-response curves and notable adverse event rates. At the American...

The Michael J. Fox Foundation (MJFF) introduced the Targets to Therapies (T2T) initiative, focusing on accelerating validation and tool development for 21 prioritized molecular targets in...

The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) recommended the authorization of five new drugs, four of which already hold US approvals. Additionally, CHMP...

The U.S. Food and Drug Administration (FDA) has unveiled a new pilot program granting biotechnology companies a priority voucher that shortens drug review times by one to two months, aiming to...