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Capsida Biotherapeutics Gene Therapy Trial Halted after Patient Death in Rare Brain Disorder Study
Capsida Biotherapeutics' clinical trial testing a gene therapy for STXBP1 encephalopathy, a rare pediatric neurological disorder, suffered a significant setback after a patient died shortly...
Eli Lilly Launches TuneLab Platform to Provide AI Drug Discovery Models to Biotech Firms
Eli Lilly introduced TuneLab, a collaborative platform offering biotech companies free access to its sophisticated artificial intelligence models developed over two decades to predict small...
Jackson Laboratory Develops Universal Nonneutralizing Antibody Cocktail Against Multiple Flu Strains
Scientists at Jackson Laboratory developed a novel antibody therapy that provides broad protection against diverse influenza A virus strains, including those with pandemic potential, by targeting...
MERCK Halts UK Research Operations, Citing Government and Funding Challenges
Merck announced it is discontinuing all research operations in the United Kingdom and scrapping plans for a £1 billion London drug research center. The decision reflects frustration over lack of...
Breakthrough Study Links Neuronal Activity to Small Cell Lung Cancer Progression via Synaptic Connections
Multiple groundbreaking studies have revealed that small cell lung cancer (SCLC) cells form functional synapses with neurons, integrating into neural circuits to promote tumor growth. This...
Salk Institute Study Links Gut Microbiome Instability to Childhood Undernutrition and Stunting
A landmark study by the Salk Institute and collaborators illuminated the critical role of the gut microbiome’s composition and function in pediatric undernutrition and growth stunting. Analysis of...
Aspect Analytics Raises €10 Million to Expand Spatial Biology Data Analysis Platform
Belgian bioinformatics company Aspect Analytics closed a €10 million Series A round to enhance and extend its cloud-based Weave platform, which integrates and analyzes multiomics spatial biology...
Novartis Buys Tourmaline Bio for $1.4 Billion to Boost Heart Disease Pipeline
Novartis announced the acquisition of Tourmaline Bio for $1.4 billion, acquiring the anti-IL-6 monoclonal antibody pacibekitug targeting atherosclerotic cardiovascular disease (ASCVD)....
Johnson & Johnson Wins FDA Approval for Bladder Cancer Drug-Device Inlexzo
The FDA approved Johnson & Johnson's drug-device combination, Inlexzo (formerly TAR-200), for treating Bacillus Calmette-Guérin (BCG)-unresponsive, non-muscle invasive bladder cancer with...
LB Pharmaceuticals Raises $285M in IPO to Advance Schizophrenia Drug LB-102
LB Pharmaceuticals raised $285 million in a Nasdaq IPO, the largest biotech offering in over half a year, exceeding initial projections. The company is developing LB-102, an oral derivative of...
AI Model PDGrapher Identifies Treatments to Reverse Disease States in Cells
Researchers at Harvard Medical School released PDGrapher, an AI model designed to predict therapeutic targets that can reverse diseased cell gene expression to a healthy state. Unlike traditional...
Small Cell Lung Cancer Forms Functional Synapses with Neurons, Promoting Growth
Groundbreaking research from Stanford Medicine and collaborators revealed that small cell lung cancer (SCLC) cells can form active synaptic connections with neurons in the brain microenvironment....
Novel Non-Neutralizing Antibody Cocktail Provides Broad Flu Protection in Mice
Scientists at Jackson Laboratory developed a cocktail of non-neutralizing antibodies targeting the conserved M2e protein of influenza A virus, demonstrating protection against nearly all tested...
Merck Ends UK R&D Efforts, Cancels London Lab Amid Industry Discontent
Merck has decided to halt all research operations in the UK and abandon its planned $1.3 billion London research center, citing insufficient governmental support for life sciences investment and...
ABCA7 Gene Variants Alter Neuronal Mitochondrial Function Linked to Alzheimer’s
New studies implicate loss-of-function mutations in the ABCA7 gene, a key lipid transporter, in disrupting mitochondrial health in neurons. These alterations contribute to Alzheimer’s disease...
AI Adoption in Healthcare: Industry Faces Challenges in NHS Integration
A University College London study reveals substantial difficulties in procuring and deploying artificial intelligence technologies within the National Health Service (NHS). Stakeholders encounter...
Cancer Immunotherapy Candidate STF-1623 Shows Promise Targeting Innate Immune Checkpoint
Researchers at Stanford University and the Arc Institute developed STF-1623, an ENPP1 inhibitor with ultralong tumor residence time aimed at blocking cancer cells' evasion of innate immune...
Novartis Buys Tourmaline for $1.4 Billion Heart Drug Play
Novartis has agreed to acquire Tourmaline Bio for approximately $1.4 billion, securing the rights to pacibekitug, a Phase 3-ready antibody targeting inflammation in atherosclerotic cardiovascular...
Johnson & Johnson Wins FDA Nod for Bladder Cancer Drug-Device Combo
Johnson & Johnson received FDA approval for Inlexzo, a drug-device combination delivering gemcitabine intravesically to treat Bacillus Calmette-Guérin (BCG)-unresponsive, non-muscle invasive...
LB Pharmaceuticals Raises $285 Million in Biotech IPO for Schizophrenia Drug
LB Pharmaceuticals debuted on Nasdaq with a $285 million IPO, the largest biotech offering since February 2025. The company is advancing LB-102, an oral drug candidate for schizophrenia derived...