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Latest Biotech News

Structure’s oral GLP‑1 pill posts 44‑week weight loss that rivals injectables

March 17, 2026

Structure Therapeutics reported 44‑week Phase 2 data showing its oral GLP‑1 agonist aleniglipron produced up to ~16% placebo‑adjusted weight loss, reinforcing the company’s claim of...

CytomX’s masked ADC posts responses in late‑line colorectal cancer — stock rallies

March 17, 2026

CytomX reported expansion‑cohort data from a Phase 1 study of Varseta‑M, a ‘masked’ conditionally activated antibody‑drug conjugate targeting EpCAM, showing objective response rates of 20–32% at...

Bicycle Therapeutics cuts 30% of workforce after regulatory setback on lead oncology asset

March 17, 2026

Bicycle Therapeutics announced a 30% workforce reduction and a strategic de‑prioritization of its Padcev challenger following an unexpected regulatory setback that extended the path to approval....

PerturbAI releases largest in‑vivo CRISPR brain atlas — dataset of 8M cells

March 17, 2026

PerturbAI emerged from stealth and publicly released an in‑vivo Perturb‑seq CRISPR atlas mapping gene function across 8 million mouse brain cells, generated with partners 10x Genomics, NVIDIA and...

Roche inks Nvidia partnership to build a large‑scale pharma 'AI factory'

March 17, 2026

Roche expanded its AI and compute ambitions by striking a deal with Nvidia to build an ‘AI factory’ intended to accelerate drug discovery and diagnostic development. The initiative follows a...

weMERFISH: whole‑embryo, 3D spatial transcriptomics advances developmental mapping

March 17, 2026

Researchers at the University of Basel published weMERFISH, an extension of MERFISH that enables three‑dimensional, whole‑embryo spatial transcriptomics over time. The platform detected...

ARPA‑H awards BioCurie up to $9.3M to build AI‑driven gene therapy manufacturing platform

March 17, 2026

ARPA‑H awarded BioCurie up to $9.3 million to develop an AI‑powered digital platform intended to speed and standardize gene therapy process development across viral and non‑viral manufacturing....

Trenchant and Invetech advance fully automated, point‑of‑care CGT AutoCell manufacturing

March 17, 2026

Trenchant BioSystems and Invetech announced a collaboration to commercialize AutoCell, a fully automated cell and gene therapy (CGT) manufacturing platform that could enable point‑of‑care...

PerturbAI exits stealth—publishes 8M-cell in vivo CRISPR atlas

March 17, 2026

PerturbAI announced it has emerged from stealth and publicly released an in vivo CRISPR Perturb‑seq atlas mapping gene function across 8 million mouse brain cells. The San Francisco startup...

AlphaFold DB expands—millions of new protein complex predictions added

March 17, 2026

EMBL‑EBI, DeepMind, NVIDIA and Seoul National University jointly released a large-scale set of AI‑predicted protein complex structures to the AlphaFold Database, dramatically expanding resources...

Generative AI drives petascale designed DNA synthesis — Nature Biotechnology

March 17, 2026

Researchers published a Nature Biotechnology paper detailing a generative‑model framework that enables petascale synthesis of designed DNA sequences for engineered biology and cell‑therapy...

Roche strikes Nvidia pact—aims to build pharma’s largest AI compute hub

March 17, 2026

Roche announced a strategic deal with NVIDIA to build an AI 'factory' aimed at accelerating drug and diagnostic development, positioning the Swiss group to compete with peers investing in...

Mayo Clinic engineers milk‑derived nanoparticles for targeted gene therapy

March 17, 2026

Mayo Clinic researchers published preclinical work on milk‑derived nanoparticles engineered to deliver targeted gene therapy to cholangiocarcinoma, an aggressive bile duct cancer. The team showed...

Structure’s oral GLP‑1 posts up to 16% weight loss — Phase 2 readout

March 17, 2026

Structure Therapeutics released 44‑week Phase 2 data showing its oral GLP‑1 candidate aleniglipron produced up to 16% placebo‑adjusted weight loss, positioning the pill as a competitive oral...

BioMarin pauses Voxzogo dosing after hip safety signal

March 17, 2026

BioMarin said it will halt dosing in certain patients across two mid‑stage Voxzogo studies after investigators flagged hip‑related safety events—cases of slipped capital femoral epiphysis...

R1 Therapeutics raises $77.5M to advance kidney disease candidate

March 17, 2026

R1 Therapeutics secured $77.5 million to advance a Phase 2b program targeting hyperphosphatemia in dialysis patients and support clinical development toward a potential market launch by the...

ARPA‑H backs BioCurie—$9.3M to digitize gene therapy manufacturing

March 17, 2026

ARPA‑H awarded BioCurie up to $9.3 million to develop an AI‑powered digital platform designed to accelerate and standardize gene therapy manufacturing across viral and non‑viral modalities....

Trenchant, Invetech partner to commercialize fully automated CGT manufacturing

March 17, 2026

Trenchant BioSystems announced a collaboration with Invetech to advance and commercialize the AutoCell platform, a fully automated cell and gene therapy (CGT) manufacturing system intended for...

Structure’s oral GLP‑1 delivers 16% weight loss – Plans phase 3

March 17, 2026

Structure Therapeutics announced Phase 2 data showing its oral GLP‑1 candidate aleniglipron produced roughly 16% placebo‑adjusted weight loss at 44 weeks. The company reported durable efficacy...

CytomX posts promising ADC data; partner exits a multi‑year T‑cell pact

March 17, 2026

CytomX Therapeutics disclosed expansion‑cohort Phase 1 data for its masked antibody‑drug conjugate Varseta‑M showing objective response rates of roughly 20–32% in heavily pretreated metastatic...