Get the Daily Brief
Latest Biotech News
Cancer Metabolism and RNA Regulation Intersect in Leukemia via IGF2BP3 Protein
UCLA researchers uncovered that Insulin-like Growth Factor 2 mRNA-Binding Protein 3 (IGF2BP3) orchestrates both metabolic reprogramming and RNA methylation to promote leukemia cell proliferation....
Innovations in Digital and Laboratory Infrastructure Foster Rapid Biotech Development
Significant expansions and collaborations are advancing biopharma infrastructure to accelerate early-stage innovation and diagnostic capabilities. Concept Life Sciences expanded its integrated...
Trump Administration Set to Implement Drug Import Tariffs Amid Industry Pushback
The Trump administration announced impending 100% tariffs on branded pharmaceutical imports effective October 1, with exemptions for companies breaking ground on U.S.-based manufacturing...
Crinetics Pharmaceuticals’ FDA Approval for Acromegaly Treatment Signals New Competition
Crinetics Pharmaceuticals has received FDA approval for Palsonify (paltusotine), marking its first approved product and the premier oral first-line therapy for adults with acromegaly who are...
U.S. Pharmaceutical Tariffs: Trump Administration Imposes 100% Import Duties to Boost Domestic Manufacturing
The Trump administration announced a 100% tariff on imports of branded pharmaceutical products effective October 1, with exemptions for companies actively building manufacturing plants in the...
Breakthrough Pan-Cancer Immunotherapy Targets Glycans to Avoid Healthy Tissue Toxicity
Researchers at the University of California, Irvine, have developed glycan-dependent T cell recruiters (GlyTRs), a novel class of immunotherapeutics that selectively target tumor-associated...
Advances in Radiation Oncology Shape Personalized Cancer Treatment at ASTRO 2025
Leading cancer centers including the University of Cincinnati, Sylvester Comprehensive Cancer Center, and MD Anderson Cancer Center revealed significant progress in radiation oncology at the 2025...
NIH Launches $87 Million Standardized Organoid Modeling Center to Accelerate Drug Development Without Animal Testing
The U.S. National Institutes of Health has granted $87 million over three years to establish the Standardized Organoid Modeling Center (SOMC), supporting the transition from traditional animal...
Arc Institute Develops Bridge Recombinase Technology for Programmable Megabase-Scale Genome Editing
Researchers at the Arc Institute have pioneered a universal gene editing platform employing bridge recombinases that facilitates large-scale genomic rearrangements in human cells, including...
Machine Learning and AI Accelerate Medical Imaging and Diagnostics in Oncology and Cardiology
Artificial intelligence and deep learning are increasingly applied to improve diagnostic accuracy and efficiency in medical imaging. Ultromics recently demonstrated enhanced echocardiogram...
Advancements in Targeted Cancer Therapeutics with ADCs and Immunotherapies
Lonza’s Synaffix has partnered with Qurient Therapeutics to develop dual-payload antibody-drug conjugates (ADCs) combining exatecan-based cytotoxics with a CDK7 inhibitor for solid tumors, aiming...
Innovative Biotechnologies Targeting Metabolism and Immune Regulation in Cancer and Neurodegeneration
Pivotal research continues to link metabolic and immune pathways in malignant and neurodegenerative diseases. UCLA scientists identified IGF2BP3 as a key regulator that reprograms metabolism and...
Trump's Pharmaceutical Tariffs Face Carve-Outs and Regulatory Uncertainty
President Donald Trump announced a 100% tariff on branded pharmaceutical imports starting October 1, aiming to incentivize domestic manufacturing. However, key exemptions for generic drugs,...
UniQure Gene Therapy Shows Promise in Slowing Huntington’s Disease Progression
UniQure Therapeutics reported positive topline results from its pivotal Phase I/II trial of AMT-130 for Huntington’s disease, meeting its primary endpoint with a statistically significant 75%...
Breakthroughs in Programmable Genome Rearrangements by Bridge Recombinases
Researchers at the Arc Institute have developed novel bridge recombinases that enable unprecedented genome engineering by performing massive, programmable DNA rearrangements spanning hundreds of...
Innovations in Immunotherapy and CAR T Cell Enhancements
New research highlights genetic modifications that enhance CAR T cell persistence and efficacy in multiple myeloma models. Using CRISPR screening, scientists identified gene knockouts such as...
AI and Machine Learning Transformations in Biotech and Diagnostics
Artificial intelligence systems are advancing capabilities from drug prescription to diagnostic accuracy. An autonomous AI helped optimize treatment to prevent graft-versus-host disease in stem...
NIH Investment Accelerates Shift from Animal Testing to Organoid Models
Building on the FDA's roadmap to reduce animal testing in drug development, the National Institutes of Health has awarded $87 million over three years to establish the Standardized Organoid...
Crinetics Secures FDA Nod for Acromegaly Drug Amid Competitive Therapeutic Landscape
Crinetics Pharmaceuticals received FDA approval for Palsonify, a once-daily oral treatment for acromegaly, offering a new option for patients ineligible for or unresponsive to surgery. The therapy...
Novel mRNA Vaccine Shows Promise Against Age-Related Macular Degeneration
Researchers at the Institute of Science Tokyo have developed a pioneering mRNA vaccine targeting pathological retinal neovascularization, a key factor in age-related macular degeneration (AMD)....