Get the Daily Brief
Latest Biotech News
ARPA-H Launches Major Programs to Expand Access to Custom Gene Editing Therapies
The Advanced Research Projects Agency for Health (ARPA-H) unveiled two nine-figure funding initiatives: THRIVE and GIVE. THRIVE focuses on accelerating design platforms for personalized gene...
Bridge Recombinases Enable Megabase-Scale Programmable DNA Rearrangements
Scientists at the Arc Institute introduced an innovative gene-editing platform utilizing bridge recombinases, naturally occurring RNA-guided DNA-modifying enzymes, to rearrange large genomic...
UC Irvine Researchers Develop Pan-Cancer Immunotherapy Targeting Glycans
University of California, Irvine experts engineered glycan-dependent T cell recruiters (GlyTRs) that selectively bind tumor-associated carbohydrate antigens, enabling potent T cell-mediated...
Novel AI and Robotics Technologies Advance Cell Analysis and Clinical Predictions
Recent breakthroughs demonstrate AI-driven single-cell analysis via an AI-powered parallel microdevice facilitating high-throughput biomolecule delivery, alongside hypersonic levitation and...
Crinetics Pharmaceuticals’ Palsonify Approvals and Market Impact
Crinetics Pharmaceuticals’ Palsonify, approved by the FDA, offers a once-daily oral treatment for acromegaly patients ineligible for surgery or with inadequate surgical response. The therapy...
Eli Lilly Expands Biotech Collaboration with San Diego Incubator Site
Eli Lilly opened its Gateway Labs incubator site in San Diego’s Torrey Pines, offering 82,514 square feet of laboratory and office space to support early-stage biotech companies. The facility aims...
Crinetics leaps into acromegaly market with FDA greenlight: Faces established giants
Crinetics Pharmaceuticals secured FDA approval for Palsonify (paltusotine), the first oral first-line therapy for acromegaly patients inadequately served by surgery or ineligible for it. This...
Trump’s pharmaceutical tariffs put biotech in crosshairs: Implementation details emerge
The Trump administration announced a 100% tariff on branded drug imports starting October 1, sparking anxiety across the biotech sector. The tariff exempts generic drugs and companies actively...
Breakthrough gene editing technology enables mega-scale DNA rearrangements in human cells
Researchers at the Arc Institute developed and optimized bridge recombinase technology for human cells, allowing programmable megabase-scale chromosomal DNA rearrangements. This RNA-guided system...
AI-driven methods surging in diagnostics, clinical trials and oncology research
Artificial intelligence continues to transform diagnostics and therapeutics across biomedical fields. Studies demonstrate AI’s capacity to enhance single-cell analysis via hypersonic levitation,...
Innovations in oncology therapeutics and clinical advances spotlighted at ASTRO 2025
Leading cancer centers revealed pivotal advances for radiation oncology at the 2025 ASTRO meeting. MD Anderson showcased data establishing stereotactic body radiation therapy (SBRT) matching...
Standardized organoid center launched by NIH to replace animal testing in drug development
The US National Institutes of Health announced the Standardized Organoid Modeling Center with $87 million in funding over three years to establish reproducible, scalable organoid research...
Pan-cancer immunotherapy breakthrough targets glycans to kill tumors while sparing healthy tissue
University of California Irvine researchers developed glycan-dependent T cell recruiters (GlyTRs), a novel class of biologics that employ velcro-like sugar-binding technology to selectively engage...
Crucial genomic discoveries advance understanding and treatment of cancer and other diseases
Recent studies unveil significant genetic insights shaping diagnosis and therapy. UCLA uncovered a key protein, IGF2BP3, linking cancer metabolism and RNA regulation in leukemia, presenting new...
Biotech financing surges with nine-figure rounds fueling innovation and expansion
Major biotech firms MBX Biosciences and uniQure attracted substantial nine-figure fundraising rounds, reflecting sustained investor confidence in life sciences despite political and economic...
Crinetics Gains FDA Approval: Oral Acromegaly Drug Challenges Injectables
Crinetics Pharmaceuticals secured FDA approval for Palsonify (paltusotine), the first oral, once-daily first-line therapy for adults with acromegaly. This rare endocrine disorder results from...
Eli Lilly’s Oral SERD Inluriyo Approved for Advanced Breast Cancer
The FDA approved Eli Lilly’s oral selective estrogen receptor degrader (SERD), imlunestrant (marketed as Inluriyo), for treating adults with advanced or metastatic estrogen receptor-positive,...
Trump Administration Enforces 100% Tariffs on Imported Pharmaceuticals
President Trump announced a 100% tariff on branded pharmaceutical imports effective October 1 unless companies are actively building manufacturing plants in the U.S., defined as at groundbreaking...
Innovations in Radiation Oncology Presented at ASTRO 2025 Conference
Leading academic cancer centers showcased groundbreaking radiation therapy advances at the 2025 ASTRO Annual Meeting. UCLA Health highlighted personalized radiation using genomic adjusted...
AI and Machine Learning Boost Innovations in Medical Diagnostics and Therapeutics
Artificial intelligence (AI) and machine learning technologies continue to transform biotech and healthcare. Novel AI models enhance accuracy in lung lesion bronchoscopy and medical diagnosis...