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Lonza and Qurient Partner on Dual-Payload Antibody-Drug Conjugates for Solid Tumors
Lonza's Synaffix platform has entered a licensing collaboration with Qurient Therapeutics to develop a novel dual-payload antibody-drug conjugate (ADC) integrating Synaffix’s exatecan technology...
Groundbreaking Soil and Plant Innovations Enhance Agriculture Sustainability and Food Security
Multiple research breakthroughs offer promising solutions for sustainable agriculture under climate challenges. A fully biodegradable hydrogel supports soilless farming in drought conditions,...
UniQure’s AMT-130 Gene Therapy Slows Huntington’s Progression
UniQure announced positive topline data from its pivotal phase I/II trial evaluating AMT-130 for Huntington’s disease (HD), demonstrating statistical significance in slowing disease progression by...
Hansa Biopharma’s Imlifidase Enables Kidney Transplants in Highly Sensitized Patients
Hansa Biopharma reported positive outcomes from a pivotal U.S. phase III trial of imlifidase, an enzyme that rapidly cleaves antibodies to facilitate kidney transplantation in highly sensitized...
Eli Lilly’s FDA Nod for Oral SERD Inluriyo in Advanced Breast Cancer
The U.S. Food and Drug Administration approved Eli Lilly’s oral selective estrogen receptor degrader (SERD), Inluriyo (formerly imlunestrant), for adults with metastatic, estrogen...
CRISPR-Enhanced CAR T Advances in Multiple Myeloma
Researchers from Mass General Brigham and the Broad Institute employed in vivo CRISPR screening to identify gene knockouts that significantly improve CAR T cell function and persistence against...
Programming Protein Interaction Kinetics to Control Therapeutics
A University of Washington-led team, including Nobel Laureate David Baker, developed a generalizable molecular on/off protein switch that modulates binder dissociation rates by up to 6,000-fold,...
Longevity Inheritance via Lysosome-Epigenome Pathway in C. Elegans
Scientists at Howard Hughes Medical Institute uncovered a mechanism explaining how longevity traits are inherited across generations in C. elegans. Lysosomal metabolic changes in parent worms...
Arc Institute’s Bridge Recombinases Enable Megabase-Scale DNA Editing
Researchers at the Arc Institute and University of California, Berkeley have engineered RNA-guided bridge recombinases to perform massive, programmable human genome rearrangements spanning...
UniQure’s AMT-130 Gene Therapy Data Send Shares Soaring
Following the announcement of AMT-130’s robust slowing of Huntington’s disease progression at 36 months, UniQure’s stock surged over 200%, reflecting strong market confidence. The trial met both...
Lonza and Qurient Therapeutics Partner on Dual-Payload ADC Development
Lonza’s Synaffix platform entered a licensing agreement with South Korea’s Qurient Therapeutics to develop a clinical-stage dual-payload antibody-drug conjugate (ADC) targeting solid tumors. The...
Claritas Rx Launches Access Analytics to Accelerate Market Insights
Claritas Rx unveiled its Access Analytics platform to address fragmented data in market access operations for commercial life science companies. The software consolidates real-time data from...
Uniqure Wins FDA Path with Gene Therapy for Huntington’s Disease
Uniqure announced a landmark success with its gene therapy AMT-130 demonstrating a 75% slowing of Huntington’s disease progression at 36 months, based on a pivotal Phase I/II study. The therapy...
FDA Approves Eli Lilly’s Oral SERD for Advanced Breast Cancer
The FDA granted approval to Eli Lilly’s Inluriyo (imlunestrant), an oral selective estrogen receptor degrader (SERD) for advanced breast cancer patients harboring ESR1 mutations. The decision is...
Hansa Biopharma’s Imlifidase Succeeds in Phase 3 Kidney Transplant Trial
Hansa Biopharma reported positive Phase 3 trial results for imlifidase, an enzyme that cleaves antibodies to enable kidney transplants for highly sensitized patients on dialysis. The trial showed...
CRISPR Gene Editing Enhances CAR T Cell Therapies for Multiple Myeloma
Researchers at Mass General Brigham and the Broad Institute have employed CRISPR screening to identify gene knockouts that improve T cell function and persistence in chimeric antigen receptor...
AI and Automation Accelerate Nanoparticle Design for Drug Delivery
Biomedical engineers at Duke University developed an integrated AI-driven platform combining automated wet lab processes with artificial intelligence to rapidly design nanoparticles optimized for...
Revolutionary Single-Cell Live-Seq Workflow Enables Longitudinal Transcriptomic Analysis
Cytosurge and Lexogen have launched a live-cell sequencing workflow integrating FluidFM cytoplasmic sampling and ultra-sensitive RNA library preparation to enable repeated transcriptomic profiling...
Breakthrough in AI-Enabled Gene Editing Kinetics Offers Safer Drug Control
A team at the University of Washington developed a novel protein on/off switch leveraging AI-guided design to facilitate rapid dissociation kinetics, accelerating cytokine signaling modulation by...
Novel Nanocomposites Enhance Electrochemical Supercapacitors
Researchers have engineered a copper oxide and barium oxide (CuO/BaO) nanocomposite exhibiting superior pseudocapacitive performance for next-generation energy storage applications. Synthesized...