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Breakthrough Dual-Payload ADC Collaboration Aims at Solid Tumors
Lonza’s Synaffix entered a licensing agreement with Qurient Therapeutics to develop a dual-payload antibody-drug conjugate (ADC) leveraging Synaffix’s clinical-stage GlycoConnect®, HydraSpace®,...
AI-Powered Diagnostic Advances: Ultromics and LungPro Models
Ultromics showcased FDA-cleared AI-enhanced ultrasound diagnostics detecting cardiac amyloidosis with improved sensitivity and earlier diagnosis at the 2025 scientific session. Meanwhile, a novel...
ARPA-H Launches Nine-Figure Programs to Scale Personalized Gene Editing
The Advanced Research Projects Agency for Health (ARPA-H) unveiled two new multiyear funding programs totaling nine figures: THRIVE, to accelerate development of custom in vivo precision gene...
Cancer Metabolism and RNA Regulation Linked via IGF2BP3 in Leukemia
UCLA researchers identified IGF2BP3 as a master regulator that rewires leukemia cell metabolism and RNA methylation pathways to promote rapid cancer proliferation. This protein enhances glycolytic...
Innovative Protein Switches Enable Safer Precision Medicines
University of Washington researchers developed engineered protein switches that precisely control therapeutic protein activity duration in the body. Unlike traditional affinity modulation, these...
New RNA-Based Therapy Reverses Osteoarthritis in Preclinical Model
A novel circular RNA (circRNA) therapeutic demonstrated profound efficacy in alleviating osteoarthritis progression in male mice through targeted protein replacement mechanisms. This approach...
Clinical and Technological Advances Highlighted at ASTRO 2025 Meeting
Leading oncology centers presented breakthroughs in radiation therapy including targeted radioactive treatments for recurrent prostate and pancreatic cancers, and long-term data confirming...
Standardized Organoid Modeling Center Launches to Replace Animal Testing
The U.S. NIH awarded $87 million to establish the Standardized Organoid Modeling Center aiming to develop reproducible protocols for organoid research, elevating its role in drug discovery and...
FDA Clears Crinetics’ Oral Treatment for Rare Hormone Disorder Acromegaly
Crinetics Pharmaceuticals secured FDA approval for Palsonify (paltusotine), the first oral once-daily therapy for adults with acromegaly, an endocrine disorder caused by excess growth hormone....
Eli Lilly’s Oral SERD Imlunestrant Approved for Advanced Breast Cancer
The U.S. FDA has approved Eli Lilly's imlunestrant (Inluriyo), an oral selective estrogen receptor degrader (SERD), for adults with estrogen receptor-positive, HER2-negative, ESR1-mutant advanced...
President Trump Imposes 100% Tariffs on Imported Branded Drugs Starting Oct. 1
President Donald Trump announced a 100% import tariff on branded pharmaceutical drugs starting October 1, with exemptions for companies actively building manufacturing plants in the U.S. This...
Lonza’s Synaffix and Qurient Collaborate on Dual-Payload ADC Development
Lonza’s Synaffix platform is partnering with Qurient Therapeutics to develop a dual-payload antibody-drug conjugate (ADC) targeting solid tumors. This collaboration combines Synaffix’s...
CAR T Cell Therapy Targets Renal Cell Carcinoma with Off-the-Shelf Approach
Researchers are advancing chimeric antigen receptor (CAR) T cell therapies targeting CD70, highly expressed in over 80% of renal cell carcinomas (RCC) but limited in normal tissues. Efforts focus...
AI and Deep Learning Improve Medical Imaging and Clinical Phenotyping
Breakthroughs in artificial intelligence are enhancing diagnostics and clinical data interpretation. Ultromics reported improved early detection of cardiac amyloidosis through FDA-cleared AI...
Novel Protein Switches Enable Real-Time Precision Control of Therapeutics
University of Washington researchers introduced engineered protein switches that regulate therapeutic protein activity by controlling binding duration rather than affinity. This innovative...
Breakthroughs in Radiation Oncology Presented at ASTRO 2025
Leading cancer centers unveiled novel advances in radiation therapy. UCLA researchers highlighted targeted radioactive therapies, innovative stereotactic body radiation techniques (SBRT), and...
mRNA Vaccine Shows Promise for Age-Related Macular Degeneration in Animal Model
Scientists at the Institute of Science Tokyo developed a novel mRNA vaccine demonstrating efficacy in mitigating pathological neovascularization characteristic of age-related macular degeneration...
Crinetics’ Palsonify Secures FDA Nod for Acromegaly – New Oral Therapy Emerges
Crinetics Pharmaceuticals gained FDA approval for Palsonify (paltusotine), the first oral once-daily therapy to treat adult acromegaly patients who are either post-surgery inadequate responders or...
Trump’s 100% Tariff on Drug Imports Threatens Small Biotechs – Industry Faces New Challenges
President Donald Trump announced a 100% import tariff on branded pharmaceutical drugs starting October 1, with carve-outs for companies actively constructing manufacturing plants in the U.S. and...
Advanced AI and Robotics Forge Breakthroughs in Biomedical Engineering
Innovations in bioengineering are reshaping therapeutic delivery and diagnostics. Carnegie Mellon scientists developed biological microscale robots, "AggreBots," from human lung cells capable of...