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Novo Nordisk Restructures Amid Market Pressures
Novo Nordisk has announced significant restructuring measures, including cutting 9,000 jobs (about 11% of its workforce) and instructing all employees to return to the office full-time. These...
Capsida Gene Therapy Trial Paused After Patient Death
Capsida Biotherapeutics has suspended its phase I/II clinical trial of CAP-002, a novel gene therapy targeting STXBP1 encephalopathy, following the death of the first pediatric patient enrolled....
LB Pharmaceuticals Raises $285M in Major Biotech IPO
LB Pharmaceuticals successfully completed an initial public offering, raising $285 million in the largest biotech IPO since February 2025. The offering exceeded earlier projections, pricing 19...
Maze Therapeutics Advances Rare Disease Pipeline and Raises Capital
Maze Therapeutics reported positive phase 1 data for MZE-782, an oral inhibitor targeting SLC6A19 with potential applications in phenylketonuria (PKU) and chronic kidney disease (CKD). The...
VedaBio Licenses Mammoth Biosciences CRISPR IP to Speed Diagnostics
VedaBio acquired a broad portfolio of CRISPR diagnostic intellectual property from Mammoth Biosciences, enhancing its amplification-free point-of-care molecular diagnostic platform. This...
New Spatial Epigenomics Portal Offers Multi-Modal Tissue Maps
A new data portal by AtlasXomics hosts spatial epigenomics datasets generated via Deterministic Barcoding in Tissue sequencing (DBiT-seq), enabling researchers to explore gene regulation in native...
FDA Advances Non-Opioid Pain Drug Development Guidance
The US Food and Drug Administration issued draft guidance designed to facilitate development of non-opioid therapies for chronic pain. The recommendations outline clinical trial design...
Lasker Awards Recognize Protein and Medical Breakthroughs
The prestigious 2025 Lasker Awards honored foundational discoveries in molecular biology and transformative medical research. Dirk Görlich and Steven McKnight received the Basic Medical Research...
New Insights into Small Cell Lung Cancer-Neuron Synapses
Recent research published in Nature reveals that small cell lung cancer (SCLC) cells can form functional synapses with neurons, integrating into neural circuits to promote tumor progression. This...
Merck Pulls Out of UK Research Amid Policy Concerns
Merck has made a decisive move to halt its research and discovery operations in the United Kingdom, including abandoning its £1 billion London lab project. The decision stems from frustrations...
Novo Nordisk Restructuring and Workforce Changes
Novo Nordisk has announced a significant restructuring plan, involving the cutting of approximately 9,000 jobs, representing an 11% workforce reduction. This strategic pivot aligns with a...
Breakthrough Cancer Research Linking Neural Mechanisms and Tumor Progression
Recent studies have unveiled that small cell lung cancer (SCLC) cells establish functional synaptic connections with neurons, integrating into the nervous system circuitry. These neural synapses...
LB Pharmaceuticals IPO Signals Biotech Market Rebound
LB Pharmaceuticals closed a $285 million initial public offering, marking the largest biotech IPO in the U.S. for 2025 to date and breaking a seven-month drought in significant public biotech...
AI and Advanced Technologies Accelerate Multi-Omics Research and Laboratory Automation
Sapio Sciences and Ultima Genomics have partnered to integrate AI-powered lab informatics with high-throughput sequencing platforms, facilitating streamlined, scalable multi-omics workflows for...
Capsida Biotherapeutics Pauses Rare Disease Gene Therapy Trial After Patient Death
Capsida Biotherapeutics has halted its Phase I/II clinical trial of gene therapy CAP-002 targeting STXBP1 encephalopathy in pediatric patients following the death of the first enrolled child. The...
FDA Approvals and Regulatory Actions in Oncology and Therapeutics
The FDA granted approval for Johnson & Johnson’s Inlexzo, a drug-device combination delivering gemcitabine directly to the bladder for patients with BCG-unresponsive non-muscle invasive bladder...
AI Models Predict Therapeutic Targets and Advance Drug Discovery
Harvard Medical School researchers have developed PDGrapher, an artificial intelligence model that improves drug discovery by predicting combinatorial therapeutic targets capable of reversing...
Nanomedicine and Novel Drug Delivery Systems in Cancer Therapy
Recent advances in nanotechnology have produced innovative drug delivery platforms for targeted cancer therapy. Researchers developed poly-L-histidine-coated mesoporous silica nanoparticles for...
Breakthrough Research on Brain Function and Neurodegenerative Disease
Novel studies reveal crucial insights into brain aging, neurodegeneration, and potential therapeutic targets. Research from Calico Life Sciences et al. demonstrates that microglial aging is...
Merck pulls UK operations: £1.3 billion London lab scrapped
Merck has abruptly terminated its planned £1.3 billion research lab in London and will discontinue all discovery research operations in the UK. Citing lack of meaningful progress in life science...