Get the Daily Brief
Latest Biotech News
Potent cross‑neutralizing antibodies neutralize Marburg and Ravn viruses
Scientists discovered a class of potent antibodies that cross‑neutralize Marburg virus and the related Ravn virus, according to a report in npj Viruses. The antibodies show broad neutralizing...
PCMT1 linked to new degron pathway on cereblon substrates
Biochemists reported that protein carboxymethyltransferase 1 (PCMT1) generates a C‑terminal degron on substrates of cereblon (CRBN), the E3 ligase adapter central to the activity of...
Diasorin wins FDA OK: 15‑minute molecular POC cleared
The US Food and Drug Administration issued 510(k) clearance and a CLIA waiver for Diasorin’s LIAISON Nes four‑plex molecular assay, enabling detection of influenza A/B, RSV and SARS‑CoV‑2 at the...
Plasma protein panel spots cancer in symptomatic patients
Researchers published a plasma protein profiling study showing a blood‑based panel can predict cancer in patients presenting with non‑specific symptoms. The lead finding: a multiplex protein...
Meta‑analysis: CAR‑T and bispecifics split outcomes in indolent B‑cell NHL
A new meta‑analysis compared chimeric antigen receptor T‑cell (CAR‑T) therapy with bispecific antibody treatments for relapsed or refractory indolent B‑cell non‑Hodgkin’s lymphomas. The pooled...
Researchers find cross‑neutralizing antibodies vs Marburg and Ravn
Scientists reported discovery of potent cross‑neutralizing human antibodies that neutralize Marburg virus and the related Ravn virus, according to a paper in npj Viruses. The antibodies target...
Senhwa pushes CX‑5461 into combo play with ADC and PD‑1 tie‑up
Senhwa Biosciences announced a clinical collaboration with BeOne Medicines to evaluate CX‑5461 in combination with an antibody‑drug conjugate (ADC) and BeOne’s marketed PD‑1 inhibitor, targeting...
Genetic screening in oncology... adoption lags despite safety gains
A MedCity News report reviewed emerging genetic screening tools that predict rare but deadly adverse reactions to common cancer drugs and improve drug selection. Despite mounting evidence of...
Antibiotic pollution accelerates resistance in Indian sewage: Nature Commun.
A Nature Communications study linked widespread antibiotic contamination in urban Indian sewage with accelerated selection for antimicrobial‑resistant bacteria and resistance genes. Researchers...
AI in biotech... roadmap to drug discovery and personalized care by 2033
An industry analysis published by BioTecNika projects that artificial intelligence will transform drug discovery pipelines and personalized medicine by 2033. The report synthesizes case studies...
Mitochondrial gene therapy: progress reported, obstacles remain
A field review assessed progress and outstanding challenges for mitochondrial gene therapy, detailing advances in delivery vectors, allotopic expression and mtDNA editing techniques. Researchers...
Vaccine targets immune evasion in EBV‑linked nasopharyngeal carcinoma
A study led by Gan et al. reported a therapeutic vaccine designed to counter immune‑evasive mechanisms in Epstein‑Barr virus (EBV)‑associated nasopharyngeal carcinoma (NPC). The vaccine stimulates...
Antibiotic runoff fuels resistance: Indian sewage study
A Nature Communications study found high concentrations of antibiotic residues in urban Indian sewage have accelerated selection for antimicrobial resistance across microbial communities....
FDA clears Diasorin molecular POC: four‑plex gives 15‑minute results
The FDA issued 510(k) clearance and a CLIA waiver for Diasorin’s LIAISON Nes four‑plex molecular assay for Flu A/B, RSV and SARS‑CoV‑2, enabling laboratory‑quality PCR testing at the point of...
Plasma protein panel detects cancer: minimally invasive screening advances
Researchers reported a plasma protein profiling approach that predicts cancer in symptomatic patients, demonstrating high sensitivity for cancers that present with non‑specific symptoms. The team...
New cross‑neutralizing antibodies discovered against Marburg and Ravn
A team publishing in npj Viruses identified potent, broadly neutralizing antibodies that target both Marburg virus and the related Ravn virus. The antibodies neutralize multiple viral strains in...
Meta‑analysis pits CAR‑T against bispecifics: efficacy and risk compared
A new meta‑analysis compared CAR‑T cell therapies and bispecific antibodies in relapsed or refractory indolent B‑cell non‑Hodgkin’s lymphomas, synthesizing efficacy and safety across trials. The...
Mitochondrial gene therapy: progress outlined — delivery remains a hurdle
A review of mitochondrial gene therapy summarized recent advances in treating mtDNA disorders and highlighted technical and regulatory challenges that remain. Authors cataloged delivery...
Conformal silicon Hall sensors... a new route for early 3‑D tumor monitoring
Engineers reported a conformal, ultrathin crystalline‑silicon Hall sensor array designed to monitor three‑dimensional tumor tissues at early stages. Published in npj Flexible Electronics, the work...
AI flags paroxysmal AF from sinus ECGs — screening gets smarter
Researchers developed AI software that detects paroxysmal atrial fibrillation (PAF) from ECGs recorded in sinus rhythm, demonstrating superior sensitivity to standard interpretation in diagnostic...