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NICU exposures linked to altered newborn brain development
A new study reported that environmental exposures in neonatal intensive care units are associated with changes in neurodevelopmental trajectories for both preterm and term infants. Researchers...
RNA‑guided STAT3 rewires CD4+ T cells in NSCLC: immunotherapy implications
Researchers uncovered an RNA‑guided mechanism by which STAT3 signaling shapes CD4+ T‑helper cell fate in non‑small cell lung cancer, linking epigenetic and epitranscriptomic regulation to...
Diasorin’s Liaison Nes Cleared: 510(k) and CLIA waiver for four‑plex
The US Food and Drug Administration issued 510(k) clearance and a CLIA waiver for Diasorin’s LIAISON Nes four‑plex molecular assay, enabling point‑of‑care PCR testing for influenza A/B, RSV and...
Broad Marburg antibodies discovered – neutralize Ravn too
Researchers identified a class of potent cross‑neutralizing antibodies that neutralize Marburg virus and the related Ravn virus, according to a report in npj Viruses. The study maps epitopes on...
CAR‑T vs bispecific... head‑to‑head meta‑analysis in indolent B‑cell NHL
A meta‑analysis compared CAR‑T cell therapy and bispecific antibody therapy for relapsed or refractory indolent B‑cell non‑Hodgkin’s lymphomas, synthesizing response and safety data across...
Plasma protein profiling predicts cancer in symptomatic patients
Researchers published a plasma protein profiling study that detects cancer in patients presenting with non‑specific symptoms, reporting a minimally invasive screening approach with high...
Antibiotic pollution drives AMR in Indian sewage: study
A Nature Communications study traced how pharmaceutical contamination in Indian urban sewage correlates with accelerated antimicrobial resistance (AMR) emergence. Researchers combined chemical...
Mitochondrial gene therapy: progress and hurdles flagged
A review outlines recent advances in mitochondrial gene therapy and the technical and translational challenges that remain. Authors summarized novel delivery systems, genome editing tools...
RNA‑guided STAT3 reshapes T cell fate in NSCLC
A study uncovered an RNA‑guided mechanism by which STAT3 signaling modulates CD4+ T helper cell differentiation within non‑small cell lung cancer (NSCLC), altering epigenetic and epitranscriptomic...
NICU environmental exposures linked to altered newborn brain development
A new study documents how environmental exposures in neonatal intensive care units (NICUs) correlate with neurodevelopmental outcomes in critically ill preterm and term neonates. Investigators...
Progenitor‑endothelial niche interaction accelerates graft healing
Researchers reported a strategy that accelerates endothelialization of 3D‑printed vascular grafts by leveraging interactions between circulating endothelial progenitor cells (EPCs) and the...
Senhwa pursues CX‑5461 plus ADC combo – clinical collaboration announced
Senhwa Biosciences announced a clinical collaboration with BeOne Medicines to evaluate CX‑5461 combined with an antibody‑drug conjugate (ADC) and a marketed PD‑1 inhibitor in cold tumors,...
FDA clears Diasorin four‑plex assay: LIAISON Nes becomes CLIA‑waived
The US Food and Drug Administration issued 510(k) clearance and a CLIA waiver for Diasorin’s four‑plex molecular assay for Flu A/B, RSV and SARS‑CoV‑2 to run on the company’s new LIAISON Nes...
Potent cross‑neutralizing antibodies discovered: Marburg and Ravn targeted
Researchers reported discovery of a new class of potent antibodies that neutralize both Marburg virus and the related Ravn virus, findings published in npj Viruses. The study characterizes...
CAR‑T vs bispecifics... meta‑analysis contrasts treatments in relapsed B‑cell NHL
A new meta‑analysis compared outcomes of CAR‑T cell therapy and bispecific antibody therapy in relapsed or refractory indolent B‑cell non‑Hodgkin’s lymphomas. The study aggregates efficacy and...
RNA‑guided STAT3 reprograms T‑cell fate in lung cancer
A team uncovered an RNA‑guided mechanism by which STAT3 signaling shapes CD4+ T helper cell fate in non‑small‑cell lung cancer (NSCLC), detailing coordinated epigenetic and epitranscriptomic...
HiSTaR maps tissue architecture: hierarchical spatial transcriptomics
Researchers Yu, J., Yuan, J., Yi, Q. and colleagues introduced HiSTaR, a hierarchical spatial transcriptomics variational autoencoder, to map spatial domains and cellular interactions in complex...
Conformal silicon Hall sensors... early 3‑D tumor monitoring
A team published a conformal, ultrathin crystalline‑silicon Hall sensor array designed for early monitoring of three‑dimensional tumor tissues. Presented in npj Flexible Electronics, the device...
AI spots hidden arrhythmia: paroxysmal AF detected from sinus‑rhythm ECGs
Researchers developed AI software that detects paroxysmal atrial fibrillation (PAF) from ECG recordings taken during sinus rhythm, addressing a major diagnostic blind spot. The model was trained...
Ovarian cancer mechanisms: DJ‑1 autophagy link and lncRNA m6A regulation
Two independent studies identified molecular drivers that promote ovarian cancer progression. One team showed that the oncogene DJ‑1 regulates autophagy through the JNK signaling pathway,...