Latest Biotech News

Pyrotinib-based neoadjuvant therapy using a pill regimen achieved pathological response rates comparable to the standard trastuzumab–pertuzumab combination in a multicenter phase II trial in...

A patient-level synthesis of 40 published cases shows nivolumab-induced hypophysitis primarily damages the pituitary’s cortisol-regulating axis, typically responds to corticosteroids, and rarely...

A rat study reports that spatially fractionated minibeam radiation preserved the efficacy of CD19-directed CAR T cells in a brain lymphoma model and extended survival compared with conventional...

A retrospective Chinese study of 81 patients with hemoptysis found CT angiography measures bronchial arteries only marginally larger than digital subtraction angiography (ID: 6c2c253e606f46d5)....

A three-round European e-Delphi process produced 70 consensus statements defining how specialist palliative care should serve patients living with stable locally advanced or metastatic cancer (ID:...

New preclinical research reports that metformin shields lymphatic vessels from mitochondrial damage caused by 5-fluorouracil and reduces lymphedema in mouse models (ID: e6d9e920130cc98f). The...

In the Phase II portion of the NRG-HN009 trial, weekly cisplatin did not significantly reduce acute toxicity compared with every-three-week dosing in patients with p16-negative locally advanced...

A pharmacovigilance analysis of nearly five million adverse-event reports concludes that liver injury after CAR T-cell therapy is predominantly early and linked to cytokine release syndrome, with...

An international trial led by University of Pittsburgh scientists reported that an optogenetic gene therapy combined with light-projecting goggles was safe and improved visual function in some...

Researchers developed a modular etching–brushing–soaking protocol to standardize lithium metal surfaces, improving reproducibility and full-cell battery performance (ID: 5db8f51035f8b91d). While...

Dual-release levodopa formulation IPX203 has received expert-consensus endorsement for use in European patients with Parkinson’s motor fluctuations, targeting improved timing of dopamine...

A large surveillance study reports that automated breast ultrasound matches handheld screening accuracy in women with dense breasts while reducing false alarms, potentially changing workflow...

Cryo-EM work has clarified how HIV-1’s Vpr protein hijacks the human CRL4(VprBP) E3 ligase to degrade diverse host targets—an upstream mechanistic map that can guide antiviral strategy...

A study in advanced science connects tumor-secreted LRG1 to neutrophil mitochondrial dysfunction and NET release, describing a pathway that destabilizes tumor vessels and undermines...

A rat study reports that grid-shaped radiation boosts CD19-directed CAR T cell efficacy in brain lymphoma, preserving survival compared with conventional radiotherapy approaches. Separately, a...

A major review and meta-analysis concludes that fetal lung drainage (pleuro-amniotic shunting) saves roughly two-thirds of babies with isolated pleural effusion and can reverse hydrops in most...

A Phase II component of the NRG-HN009 trial finds weekly cisplatin does not significantly reduce acute toxicity versus every-three-week dosing in p16-negative locally advanced head and neck...

A meta-analysis links long-term metformin use with peripheral neuropathy risk, attributing part of the association to vitamin B12 depletion affecting about a third of treated patients. A nested...

An AI system using routine MRI scans reports the ability to detect subjective cognitive decline—the earliest preclinical stage of Alzheimer’s—though the work frames performance around clinically...

An open-source R workflow called SLR Suite aims to make systematic literature reviews reproducible by bundling bibliometrics, TCCM coding, and version-controlled controls into a single...