Latest Biotech News

Two post-marketing bridging studies presented work validating that commercially available companion diagnostics can reliably identify patients eligible for tumor-agnostic pembrolizumab in...

A regulator-mandated Nordic registry study has found no increased pancreatic cancer risk among semaglutide users, using nationwide data from Denmark, Sweden, and Norway. The analysis compared more...

Johns Hopkins Medicine researchers have supported the first FDA-cleared rapid urine test for invasive aspergillosis after clinical validation. The work is designed to improve early diagnostic...

A first-in-human study reports that roginolisib, a conformation-selective PI3Kδ inhibitor, is tolerable in advanced cancers, with survival signals reported in metastatic uveal melanoma. The trial...

A proof-of-concept CT radiomics model reported mixed results for predicting early response to radiotherapy in elderly esophageal cancer patients. The study found performance instability under...

Lund University researchers report that precision-cut bladder tumor slices preserve immune cells and functional activity for up to six days, enabling ex vivo drug testing. The results showed...

A modelled analysis of two oncology units suggests that asymptomatic colonized patients drive the majority of transmission events that lead to new C. difficile colonizations. In surveillance data...

A randomized crossover trial found that wearable hip exoskeleton walking after meals significantly reduced glucose spikes in adults with type 2 diabetes compared with unassisted walking. The study...

A mixed-methods implementation evaluation reported that virtual family-centered rounds in the NICU improved participation and communication, particularly for families facing structural barriers....

Researchers describe an explainable AI system for outlining diabetic foot ulcers from clinical photographs, emphasizing attribution for where the model “looked” when making decisions. The work,...

A rapid urine test for invasive aspergillosis cleared its way through the FDA after clinical validation work from Johns Hopkins Medicine. The clearance centers on using urine as a faster sampling...

Merck reported post-marketing bridging study results confirming that two commercially available companion diagnostics can reliably identify patients eligible for pembrolizumab in dMMR/MSI-H solid...

A first-in-human study reported initial safety and survival signals for roginolisib, a conformation-selective PI3Kδ inhibitor, in advanced cancers. The trial found the agent well tolerated, with...

Nine European Parkinson’s specialists issued consensus recommendations for using a newly approved dual-release levodopa formulation, IPX203, specifically for patients experiencing motor...

An AI-assisted design pipeline delivered a new gallium-68 PET tracer, [68Ga]Ga-DOTA-FZPF, targeting PARP-1, which has now completed first-in-human evaluation in breast and ovarian cancer patients....

Lund University researchers showed that precision-cut bladder tumor slices can keep immune cells alive and functional ex vivo for up to six days. In experiments, the tissue-slice platform...

A study in China validated a urine-based tuberculosis adherence test that uses patient-submitted smartphone images to check medication intake. Across 1,655 submitted photos, 72% were...

Researchers at the University of Oxford reported that a specialized human microglia population shields dopamine neurons in Parkinson’s disease by selectively removing alpha-synuclein aggregates...

A multicenter Phase III trial found that intravenous tirofiban did not outperform standard oral antiplatelet therapy for 90-day functional outcomes in acute branch atheromatous disease-related...

A new study reports that the macrophage enzyme MMP14 generates soluble semaphorin 4D, helping build an immunosuppressive tumor microenvironment that excludes anti-cancer T cells. The findings...