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PanMAN: New compression method slashes pangenome storage needs
Researchers published PanMAN (Pangenome Mutation‑Annotated Network), a data structure and compression approach in Nature Genetics designed to dramatically reduce storage and compute burdens for...
MINT nanoparticles: disease‑responsive mRNA targets damaged cartilage
Mass General Brigham researchers reported a disease‑severity‑responsive nanoparticle platform (MINT) that preferentially delivers ghrelin mRNA to cartilage regions undergoing glycosaminoglycan...
Ocugen posts positive mid‑phase gene‑therapy reads—GA program advances
Ocugen reported interim Phase 2 data for its geographic atrophy gene therapy program showing positive signals from a limited patient cohort. Company statements said the candidate demonstrated...
Oxford Biomedica confirms takeover talks with EQT — CMO sector under M&A lens
Oxford Biomedica, a major contract manufacturer for cell and gene therapies, confirmed takeover talks with private equity investor EQT after rejecting multiple bids it deemed to undervalue the...
MRD validation framework lands: BloodPAC issues protocols, Veracyte plans TrueMRD launch
BloodPAC published standardized analytical-validation protocols for tumor‑informed circulating tumor DNA (ctDNA) assays, setting a common blueprint for how companies should demonstrate limit of...
Tecvayli survival data... J&J claims earlier multiple‑myeloma benefit
Johnson & Johnson reported Phase 3 results showing Tecvayli reduced risk of disease progression or death versus standard regimens in patients who relapsed after frontline therapy, with the company...
Big tech and lab giants double down on AI: billion‑dollar labs and instrument deals
NVIDIA and Eli Lilly announced a five‑year, $1 billion co‑innovation lab to deploy large‑scale AI computing and models for drug discovery, signaling a major industry pivot to tightly integrated...
Boston Scientific to buy Penumbra: $14.5B deal expands thrombectomy footprint
Boston Scientific agreed to acquire Penumbra for about $14.5 billion in cash and stock, a deal that would add Penumbra’s thrombectomy and embolization platforms to Boston Scientific’s...
Oxford Biomedica confirms EQT interest: takeover talks acknowledged
Oxford Biomedica, a major contract‑manufacturer for cell and gene therapy, confirmed it has engaged in takeover talks with private equity investor EQT after turning down prior unsolicited bids the...
Cellares leases Leiden hub: automated cell‑therapy IDMO expands into Europe
Cellares signed a long‑term lease at Leiden Bio Science Park for a new Integrated Development and Manufacturing Organization (IDMO) Smart Factory that will serve as the company’s European...
Novo Nordisk Foundation backs BII: DKK 5.5B to scale Danish biotech incubator
The Novo Nordisk Foundation pledged up to DKK 5.5 billion (about €736 million / ~$857 million) to the BioInnovation Institute (BII) to expand operations, increase the number of startups supported...
Caldera launches with $112M... China‑sourced bispecific enters Phase 1
Caldera Therapeutics emerged from stealth with $112.5 million in combined Series A and A‑1 financing to advance CLD‑423, a dual‑targeting bispecific licensed from China’s Qyuns Therapeutics for...
Scribe readies first CRISPR therapy: clinic start targeted for summer
Scribe Therapeutics, a company developing therapeutics based on novel CRISPR enzymes, said it plans to begin testing its first gene‑editing therapy in the clinic this summer. The program...
Illumina unveils Billion Cell Atlas... massive dataset to train drug‑discovery AI
Illumina launched the Billion Cell Atlas, an initial installment of a planned five‑billion‑cell genetic perturbation dataset built in partnership with AstraZeneca, Merck and Eli Lilly, intended to...
Boston Scientific to buy Penumbra — $14.5B deal and device nod
Boston Scientific announced an agreement to acquire Penumbra for about $14.5 billion, a transaction aimed at expanding Boston Scientific’s presence in thrombectomy and embolization markets....
NVIDIA deepens lab bets: $1B with Lilly, Thermo Fisher tie-up
NVIDIA and Eli Lilly unveiled a five-year, $1 billion collaboration to build an AI co‑innovation lab focused on drug discovery, committing compute and model development to accelerate in‑silico...
BloodPAC issues MRD validation protocols — companies ready to commercialize
The Blood Profiling Atlas in Cancer (BloodPAC) consortium published generic protocols for analytical validation of tumor‑informed circulating tumor DNA (ctDNA) assays for minimal residual disease...
Cellares signs lease for European Smart Factory at Leiden Bio Science Park
Cellares signed a long‑term lease for a Smart Factory at Leiden Bio Science Park that will serve as the company’s European headquarters and regional integrated development and manufacturing...
J&J’s Tecvayli posts positive Phase 3 readout in earlier myeloma
Johnson & Johnson reported positive Phase 3 survival outcomes for Tecvayli (teclistamab) in an earlier‑line multiple myeloma setting, supporting the drugmaker’s strategy to expand use beyond later...
Natera doubles down on Signatera: ASPs, tech upgrades and reimbursement bets
Natera told investors that Signatera drove record growth and will remain a revenue engine in 2026, with Q4 being the company’s fastest‑growing quarter for the MRD test. Management flagged expected...