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PanMAN compresses pangenomes—big genomics storage meets efficiency
Researchers published PanMAN (Pangenome Mutation-Annotated Network), an evolutionary compression data structure that encodes phylogenies, mutations and whole-genome alignments to dramatically cut...
CLASSIC: AI accelerates genetic circuit design in human cells
Researchers at Rice University unveiled CLASSIC, a combined long- and short-read sequencing approach that, together with AI/ML, enables ultra-high-throughput mapping of synthetic genetic circuit...
dSHERLOCK: digital CRISPR diagnostics quantify Candida auris and resistance
A Wyss Institute team reported dSHERLOCK, a digital CRISPR-based assay that quantifies Candida auris load and resistance mutations from swab samples using single-molecule microarrays and a...
Eikon eyes IPO as clinical-stage pipeline powers public push
Eikon Therapeutics filed SEC paperwork signaling intent to pursue a public listing on Nasdaq to fund advancement of its clinical-stage oncology pipeline. The company—backed by more than $1.1...
Tecvayli survival gains in earlier myeloma – J&J releases Phase 3 readouts
Johnson & Johnson reported that Tecvayli produced a substantial survival and disease-control benefit in a Phase 3 study of earlier-line multiple myeloma. In the MajesTEC-9 and related trials J&J...
Boston Scientific moves to buy Penumbra for $14.5B – deal to expand thrombectomy portfolio
Boston Scientific announced a definitive agreement to acquire Penumbra for about $14.5 billion, combining Boston Scientific’s cardiovascular platform with Penumbra’s thrombectomy and embolization...
Novo Nordisk Foundation pledges up to €736M to scale BioInnovation Institute – decade-long funding
The Novo Nordisk Foundation committed up to DKK 5.5 billion (~€736 million) to the BioInnovation Institute (BII) for 2026–2035 to expand startup support, geographic reach and scale the number of...
Lilly and NVIDIA form $1B AI drug-discovery lab: in silico first, wet lab feedback loop
Eli Lilly and NVIDIA announced a $1 billion co-innovation lab to accelerate AI-driven drug discovery, pairing NVIDIA’s BioNeMo and NeMo platforms with Lilly’s drug discovery teams. The partnership...
Thermo Fisher and NVIDIA partner to embed AI across instruments and lab workflows
Thermo Fisher Scientific said it will collaborate with NVIDIA to integrate AI infrastructure into scientific instruments and laboratory software, combining Thermo Fisher’s instrumentation...
Natera, Veracyte push MRD commercialization – labs add sequencing upgrades and launch plans
Two diagnostics companies unveiled plans that accelerate commercial minimal residual disease (MRD) testing: Natera said its Signatera assay delivered record growth in Q4 and will roll out a...
BloodPAC issues MRD analytical-validation protocols – industry standardization move
The Blood Profiling Atlas in Cancer (BloodPAC) consortium published generic analytical-validation protocols for tumor‑informed circulating tumor DNA (ctDNA) assays used to monitor minimal residual...
PanMAN compresses pangenomes – new data structure cuts storage and speeds analyses
Researchers published PanMAN (Pangenome Mutation-Annotated Network), a data structure and compression method that encodes phylogeny, mutations and whole-genome alignments to dramatically reduce...
Cellares signs lease for Leiden Smart Factory – European cell‑therapy IDMO hub
Cellares secured a long‑term lease in Leiden Bio Science Park to establish a Smart Factory and serve as its European integrated development and manufacturing organization (IDMO) headquarters. The...
AI designs genetic circuits at human‑cell scale – CLASSIC maps ultra‑high‑throughput design space
Researchers introduced CLASSIC, a method combining long‑ and short‑read sequencing with AI/ML to design, build and map hundreds of thousands to millions of genetic circuit variants in human cells,...
Tecvayli: J&J shows major survival gain in Phase 3
Johnson & Johnson reported Phase 3 results showing Tecvayli (a dual‑targeting T‑cell engager) produced a large survival and progression benefit in relapsed multiple myeloma. In the MajesTEC‑9...
Boston Scientific to buy Penumbra for $14.5B – Deal expands thrombectomy reach
Boston Scientific agreed to acquire Penumbra for approximately $14.5 billion, a cash‑and‑stock deal that gives the acquirer expanded thrombectomy and embolization capabilities. Penumbra makes...
Agenus-Closes $141M deal with Zydus — U.S. biologics capacity secured
Agenus finalized a $141 million strategic collaboration with Zydus Lifesciences to accelerate global development and commercial readiness for its BOT+BAL immunotherapy combination. The agreement...
Cellares inks lease in Leiden – European smart factory for cell therapies
Cellares signed a long‑term lease for a Smart Factory at Leiden Bio Science Park to serve as its European headquarters and expand automated cell‑therapy development and manufacturing capacity. The...
NVIDIA, Lilly and Thermo Fisher... AI deals scale up lab automation
Two major partnerships announced at JPM highlight an acceleration of AI investments across drug discovery and laboratory workflows. NVIDIA and Eli Lilly unveiled a $1 billion co‑innovation lab to...
TrueMRD and standards: Veracyte, BloodPAC push MRD toward clinic
Veracyte outlined plans to launch its TrueMRD minimal residual disease test in the first half of the year with an initial indication in muscle‑invasive bladder cancer and a pipeline across breast,...