Latest Biotech News

A Phase Ib trial of a personalized neoantigen dendritic cell vaccine in newly diagnosed glioblastoma reported early clinical activity, according to results published in Nature Communications. The...

Researchers unveiled small-molecule-controlled CRISPR editing systems in living tissues, publishing in Science Translational Medicine. Led by Dr. Wang Yu at the Shenzhen Institutes of Advanced...

ATB Therapeutics detailed a new ADC-adjacent format designed to widen the therapeutic window, presenting its antibody-peptide “atbodies” at the Antibody Engineering and Therapeutics conference in...

Brightpath Biotherapeutics submitted an Investigational New Drug (IND) application to the FDA to start a Phase I trial of BP-2202 in the United States for multiple myeloma, according to the...

Researchers from Harvard Medical School unveiled COMPASS, an AI model built to predict patient response to immune checkpoint inhibitors (ICIs), with results described as improving accuracy in...

Insilico Medicine and Takeda announced a collaboration for AI-driven drug discovery, with Insilico leading molecule identification under predefined scientific and early development criteria....

Merck Sharp & Dohme disclosed new benzimidazole derivatives that inhibit the NLRP3 inflammasome, expanding its disclosed chemistry around inflammasome modulation. The patent describes compounds...

A newly reported PGK1 inhibitor showed efficacy in pancreatic cancer models, with the compound demonstrating potent target inhibition in vitro. The report describes dose-dependent suppression in...

The University of Edinburgh disclosed new benzoxazol mTOR (FRAP1) inhibitors, describing potential therapeutic use across cancer, autoimmune and inflammatory conditions, metabolic disease,...

Research described Natural Language Processing (NLP) tools that outperform ICD-10 coding in capturing clinically relevant information, highlighting limitations of structured diagnosis coding for...

A phase Ib clinical trial in newly diagnosed glioblastoma reported promising activity for a personalized neoantigen dendritic cell vaccine that pulses autologous dendritic cells with...

Researchers reported in Science Translational Medicine two small-molecule-controlled genome editing systems—PRINCE and Little Prince—that keep CRISPR activity largely silent without drug and...

Brightpath Biotherapeutics Co. Ltd. filed an Investigational New Drug (IND) application with the FDA to initiate a U.S. phase I trial of BP-2202 for multiple myeloma, under NCT07667868. The...

Insilico Medicine and Takeda announced a collaboration in drug discovery, with Insilico leading AI-driven molecule identification under predefined scientific and early development...

Harvard Medical School researchers developed COMPASS, an AI model designed to predict patient response to immune checkpoint inhibitors (ICIs), and reported that it outperforms ICD-10-based...

New research reported that natural language processing (NLP) can capture clinically relevant information more accurately than ICD-10 coding, a finding aimed at improving downstream clinical...

ATB Therapeutics described at an antibody engineering conference how its antibody-peptide fusion approach, branded as “atbodies,” is engineered to extend the ADC therapeutic window by targeting...

Researchers reported progress on an eye preservation device—Eye-in-a-Care-Box (ECaBox)—designed to maintain freshly removed eyeballs using oxygen-rich perfusion via the eye’s artery. In...

Independent reports described multiple early-stage inhibitor programs across oncology targets, including a novel PGK1 inhibitor showing dose-dependent suppression in pancreatic cancer assays. The...

Countable Labs introduced a single-molecule precision PCR platform aimed at improving rare-event detection and run-to-run reproducibility in applications such as viral titer testing, vector copy...