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Sage Therapeutics Acquisition by Supernus Pharmaceuticals
Supernus Pharmaceuticals is acquiring Sage Therapeutics for up to $795 million, securing rights to Sage's postpartum depression drug Zurzuvae. The acquisition follows Sage's decline from a $9...
Breakthroughs in Nanoneedle Technology for Painless Diagnostics
Scientists at King's College London developed a cutting-edge nanoneedle patch featuring tens of millions of microscopic silicon-based needles. This technology is poised to revolutionize...
AI and Imaging Genomics Integrate for Precision Medicine
Imaging genomics, combining multi-modal imaging technologies with omics data, is evolving with the aid of AI and deep learning to decode complex disease mechanisms at molecular levels. This...
Advancements in Epigenetics and Pulmonary Disease Research
Recent studies shed light on epigenetic regulation mechanisms in persistent pulmonary hypertension of the newborn (PPHN) and male reproductive toxicity linked to PFAS exposure. Researchers...
Innovations in Cancer Therapy and Diagnostics
Cutting-edge research spans multiple fronts including an algorithm, TACIT, that accelerates cell type classification in multiplexed imaging; multifunctional nanoparticles allowing bimodal...
Regulatory Updates and Market Activity in Biotech
Regulatory agencies continue to adjust resource allocations and policy frameworks impacting drug development timelines, oversight of lab-developed tests, and clinical trial acceleration, as...
Environmental and Public Health Insights Affecting Biotech and Healthcare
Emerging research reveals environmental factors impacting human and ecosystem health, from PFAS-degrading bacteria discovered in Veneto soil to artificial light extending urban growing seasons...
Sarepta halts Duchenne gene therapy after second liver failure death
Sarepta Therapeutics has suspended shipments of its Duchenne muscular dystrophy gene therapy, Elevidys, for non-ambulatory patients following a second fatal case of acute liver failure (ALF). Both...
Supernus to acquire Sage Therapeutics for postpartum depression drug
Supernus Pharmaceuticals is acquiring Sage Therapeutics for up to $795 million, adding the FDA-approved postpartum depression treatment Zurzuvae to its portfolio. The acquisition follows a series...
BioNTech acquires CureVac to consolidate mRNA oncology efforts
BioNTech has finalized an all-stock acquisition of CureVac valued at approximately $1.25 billion, bringing the German mRNA vaccine competitor under its umbrella as a subsidiary. The merger...
AI and machine learning advancements in biotech drug development
Recent developments highlight the expanding role of AI and machine learning in accelerating drug discovery and diagnostic capabilities. University of Sheffield and AstraZeneca unveiled MapDiff, an...
New diagnostic and therapeutic technologies in oncology and infectious diseases
Innovations in diagnostics and treatments are advancing rapidly. King's College London researchers developed a nanoneedle patch offering painless tissue molecular sampling, potentially replacing...
Clinical and translational advances in neonatal care and pulmonary diseases
Significant progress has been made in understanding and managing neonatal and pulmonary conditions. A study elucidated cardiorespiratory improvements following transcatheter closure of patent...
Regulatory and funding landscape shifts impacting biotech innovation
Biotech innovation faces evolving regulatory and financing environments. FDA Commissioner Marty Makary is planning further agency consolidations aimed at operational efficiency amid staffing...
Gene editing and CRISPR patent disputes advance
The ongoing legal battle over CRISPR-Cas9 patent rights has taken a new turn following a US appeals court decision favoring the University of California and University of Vienna. The ruling...
Breakthroughs in molecular biology and cancer research tools
Advances in molecular tools and algorithms are propelling cancer and biomedical research. TACIT, a novel AI-driven algorithm developed by Virginia Commonwealth University, accelerates cell-type...
Emerging therapies and diagnostics in metabolic and autoimmune diseases
Recent clinical and preclinical research showcases novel treatment developments. A South Korean biotech disclosed promising MASH trial results for its dual GLP-1/glucagon receptor agonist with...
Sarepta Gene Therapy Halted After Second Liver Failure Death
Sarepta Therapeutics has suspended shipments of its gene therapy Elevidys for Duchenne muscular dystrophy (DMD) in non-ambulatory patients after a second fatal case of acute liver failure was...
Supernus Acquires Sage Therapeutics to Expand CNS Portfolio
Supernus Pharmaceuticals has agreed to acquire Sage Therapeutics for approximately $561 million upfront, plus contingent value rights potentially increasing the deal to $795 million. The...
Breakthrough AI Tool Uncovers Hidden Protein Variants for Precision Medicine
Researchers at UCLA and the University of Toronto introduced moPepGen, an advanced computational algorithm improving detection of hidden genetic mutations at the protein level. The tool excels by...