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KRAS G12C in lung cancer
Genentech reported superior phase III results for divarasib (KRAS G12C) in previously treated non-small-cell lung cancer, signaling a potential step-change versus the established class of KRAS...
Kidney disease R&D partnerships (AstraZeneca–CSPC)
AstraZeneca extended its China drug-development footprint with a new pact with CSPC Pharmaceutical covering two kidney disease candidates. The deal includes a $30 million upfront payment and is...
Acquisitions for immune and rare-disease cell therapy (United Therapeutics–Thymmune)
United Therapeutics moved to broaden its cell-therapy pipeline by paying $140 million to acquire Thymmune Therapeutics, targeting thymus-derived regenerative approaches. The upfront payment is...
Regenerative medicine device path to market (Bellaseno scaffold trial, J&J licensing)
Bellaseno accelerated development of its absorbable breast scaffold after a faster-than-expected pivotal trial trajectory in Australia and a new licensing deal with Johnson & Johnson’s Mentor...
CRISPR gene editing under drug control
Researchers unveiled small-molecule-controlled CRISPR systems designed to switch genome editing on only when dosing triggers are present. In a Science Translational Medicine paper, a team led by...
Complement receptor biology for drug targets (C5aR2)
A research team reported molecular underpinnings for C5aR2, a complement receptor previously described as atypical in signaling behavior. The work, focused on C5aR2’s unique signaling and...
Clinical trial readouts: PTSD wearable neuromodulation clears for veterans
Neurovalens received FDA de novo clearance for Modius Spero, a wearable neuromodulation device intended to reduce PTSD symptoms. The treatment is designed for at-home use with 30-minute daily...
Oncology companion diagnostics and clinical translation (One Biosciences–Adcytherix)
One Biosciences moved its single-cell profiling platform into clinical studies through an effort alongside Adcytherix. The collaboration advances OneMap, a single-nuclei RNA-seq-based assay...
Biopharma funding momentum (biopharma financings in H1 2026)
Biopharma financings accelerated in the first half of 2026, with total funding reported at $59.76 billion across 567 deals—more than double the $29.53 billion raised in H1 2025. The year-over-year...
Early-stage financing for IPF (Celea Therapeutics)
Celea Therapeutics raised $180 million to advance deupirfenidone into late-stage development for idiopathic pulmonary fibrosis. The PureTech-backed company said the venture round will fund a move...
KRAS G12C lung cancer readouts
Roche’s Genentech unit reported first-look Phase 3 results for divarasib in previously treated KRAS G12C non-small-cell lung cancer, using the head-to-head Krascendo 1 trial design. The company...
FDA-linked device progress for brain hemorrhage risk reduction
Aurenar’s V-Link received FDA breakthrough device designation after early clinical data suggested it reduced cerebral vasospasm by more than 40%, according to the report. The device is designed as...
Cell therapy deal: United Therapeutics acquires thymic cell platform
United Therapeutics agreed to pay $140 million to acquire Thymmune Therapeutics, targeting preclinical and rare-disease regenerative cell therapies focused on thymus function. The upfront payment...
Gene editing under pharmacologic control
A research team led by Wang Yu at the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences reported drug-controllable CRISPR genome editing systems in Science...
Next-generation ADC engineering to expand therapeutic window
ATB Therapeutics presented data supporting its “atbodies” platform—antibody-peptide fusion constructs designed to address ADC off-target toxicities and narrower therapeutic windows. At the...
Immunotherapy response prediction via AI model
Researchers led by Associate Professor Marinka Zitnik at Harvard Medical School introduced COMPASS, an AI model designed to predict patient response to immune checkpoint inhibitor therapy. The...
AstraZeneca/CSPC kidney collaboration renewal
AstraZeneca expanded its China partnership with CSPC Pharmaceutical through a kidney disease discovery pact totaling up to $1.7 billion. The report says AstraZeneca will pay a $30 million upfront...
Rare pulmonary fibrosis biotech fundraising
Celea Therapeutics, backed by PureTech, raised $180 million to advance deupirfenidone for idiopathic pulmonary fibrosis. The reported venture round is intended to move the program into late-stage...
Secure analytics platform for genomic research in rare disease and cancer
Genomics England and Lifebit will develop a trusted research environment to support cancer and rare disease studies. The partnership is described as creating secure, controlled digital workspaces...
Biomanufacturing throughput: single-molecule PCR counting platform
Countable Labs reported progress on a PCR platform designed for single-molecule precision quantification, aiming to improve sensitivity and run-to-run reproducibility versus conventional...